RESUMO
SUMMARY Erysipelatoid Carcinoma (EC), also known as Inflammatory Metastatic Carcinoma, is a rare form of cutaneous metastasis, secondary to an internal malignancy, more often related to breast cancer. Clinically, the lesion has a well-marked, bound erythematous appearance, much like an infectious process, such as erysipelas and cellulitis, these being the most common differential diagnoses. It is characterized by an acute or subacute appearance with an erythematous plaque, sometimes hot and painful, being more often situated in the primary tumor vicinity, especially in the thorax wall in the region of a mastectomy due to breast cancer. Here we present the case of a 75-year-old patient with ductal infiltrated carcinoma for 3 years, who presented an acute erythematous and infiltrated plaque in the region of a previous mastectomy, with a final diagnosis of EC.
Assuntos
Humanos , Feminino , Idoso , Neoplasias Cutâneas/secundário , Carcinoma Ductal de Mama/secundário , Erisipeloide/patologia , Neoplasias Inflamatórias Mamárias/patologia , Neoplasias Cutâneas/diagnóstico , Neoplasias Cutâneas/patologia , Tórax , Mama , Neoplasias da Mama/cirurgia , Neoplasias da Mama/patologia , Carcinoma Ductal de Mama/patologia , Diagnóstico Diferencial , Erisipeloide/diagnóstico , Eritema/patologiaRESUMO
RESUMO O pseudotumor esclerosante de órbita é um subtipo raro de pseudotumor inflamatório idiopático de órbita. É mais comum em adultos e apresenta diagnóstico de exclusão. A primeira linha de tratamento são os esteroides. O subtipo esclerosante apresenta resposta moderada aos esteroides devido à predominância de fibrose e colágeno na histologia. Relatamos o caso de um paciente com diagnóstico histológico de pseudotumor esclerosante de órbita que teve boa resposta ao tratamento com corticoide associado à azatioprina.
ABSTRACT Sclerosing orbital pseudotumor is a rare subtype of idiopathic orbital inflammatory pseudotumor. It's more common in adults and presents diagnosis of exclusion. Steroids represent the first option of treatment. The sclerosing orbital pseudotumor subtype shows moderate response to steroids due to the predominance of fibrosis and collagen in its histology. We report on a case of a patient with histologic diagnosis of sclerosing orbital pseudotumor successfully treated with corticosteroid associated with azathioprine.
Assuntos
Humanos , Masculino , Adulto , Pseudotumor Orbitário/diagnóstico , Azatioprina/uso terapêutico , Biópsia , Prednisona/uso terapêutico , Pseudotumor Orbitário/patologia , Pseudotumor Orbitário/tratamento farmacológico , Túnica Conjuntiva/patologia , Cápsula de Tenon/patologia , Microscopia com Lâmpada de Fenda , InflamaçãoRESUMO
The pathological changes and morphological features of fibrinous membrane formation on the posterior chamber lens were studied in rabbits with Irj ght microscopy and scanning electron microscopy. It was found that there were fibrinous membrane, inflammatory cells and pigment deposits on the intraocular lens (IOL) surface. On the 1st postoperative day fi rinous membrane on IOL was formed, on the 7th postoperative day enlarged markedly, on the 14th postoperative day reduced in size. It is und fothat the fibrinous exudate is the basic constituent of the membrane. The membrane on the surface of IOL is composed of fibrin along with macrophages, fibroblastlike cells and giant cells,and eventually fibrosis occurs. The fibrinous membrane and inflmmatory cells on IOL accumulate primarily on the lens edge, optical portion, positioning hole of IOL, and haptic-optic junction. It is suggestedthat fibrinous membrane formation on IOL is closely related to the irritation of PMMA IOL, the breakdown of blood-aqueous barrier and the immune response.