Determination of mineral oil mist in workplace air using infrared spectrophotometry / 中国职业医学

Objective To establish an infrared spectrophotometric method for determination of mineral oil mist in workplace air. Methods The mineral oil mist in workplace air was sampled with glass fiber filter membrane and eluted with carbon tetrachloride. Petroleum-like standard solution of carbon tetrachloride was used as the calibration standard, and quantitative analysis was performed using infrared spectrophotometric oil analyzer. Results The sampling efficiency of the glass fiber filter membrane ranged from 94.8% to 99.2%, and the extraction efficiency ranged from 95.6% to 104.2%. The linear range of mineral oil mist was 1.00-120.00 mg/L, with a correlation coefficient of 0.999 4. The detection limit was 0.52 mg/L, and the quantification limit was 1.74 mg/L. The average recovery rate ranged from 98.8% to 104.1%. The within- and between- run relative standard deviations were 2.2%-6.4% and 2.3%-5.2%, respectively. The samples were stable at room temperature for seven days. This method could be used for air sampling of mineral oil mist in workplaces where mineral oil is used. Conclusion The method is sensitive, accurate, and efficient, which is suitable for determining the concentration of mineral oil mist in workplace air.

Identification of Ranunculus ternatus by Fourier Transformation Infrared Spectrophotometry(FT-IR) / 中国药房

OBJECTIVE:To identify the medical material Ranunculus ternatus. METHODS: Potassium bromide was used for tabletting.The medical material Ranunculus ternatus and its isogeneric plants were analyzed by using infrared spectrometry.RESULTS:The infrared spectrogram of the medical material Ranunculus ternatus was distinctive and somewhat different from those of its isogeneric plants.CONCLUSION:Fourier transformation infrared spectrometry could be used for the identification of Ranunculus ternatus in that it is simple,rapid,reproducible and specific.

The Analysis of the Cholesterol Contents of Intrahepatic Duct Stones in the West Gyeongnam Region

PURPOSE: Hepatolithiasis is a recurrent disease and common in Far East Asia. In Korea, almost all intrahepatic duct (IHD) stones were pigment stones 30~40 years ago. The nationwide cooperative study showed a higher cholesterol content of IHD stones compared to the previous data. Some reports have shown a close relationship between urbanization and the cholesterol content of stones. The purpose of this study was to evaluate the cholesterol content of IHD stones in the West Gyeongnam region and evaluate the associated clinical and demographic variables. METHODS: The IHD stones were removed surgically from twenty patients who had hepatolithiasis between July 2005 and April 2007. The stones were grouped by their gross findings. The cholesterol contents were measured quantitatively by infrared spectrophotometry and compared with the clinical variables. RESULTS: Among twenty patients, 19 had pigment stones and only one had gross evidence of a cholesterol stone. The cholesterol content of the stones were 30%~50% in 13 patients, 50~70% in 6 patients and over 70% in one patient. In urban patients, the cholesterol contents of the IHD stones were higher (567.029 mg/g) than in rural patients (421.822 mg/g)(p<0.05). All stones in rural patients were pigment stones; the stones of urban patients consisted of 5 pigment, 6 mixed and 1 cholesterol stone (p<0.05). CONCLUSION: The mean cholesterol content of the IHD stones was 508.946 mg/g; the content of the stone was significantly related to the residence of the patients. These results suggest that the cholesterol content of IHD stones are likely to increase in West Gyeongnam as urbanization increases.

Relations of Stiff Shoulders with Deep Hemodynamics Values / 日本温泉気候物理医学会雑誌

Poor circulation is considered to be a cause of stiff shoulders, but there have been no studies on deep hemodynamics and the subjective estimation/palpation of stiff shoulders. We evaluated the relationship between deep hemodynamics and the degree of the subjective estimation/palpation of stiff shoulders by near-infrared spectrophotometry.<br>The subjects were 146 patients who visited our center and 23 healthy volunteers. Deep hemodynamics (tissue oxygen saturation: StO₂, total hemoglobin concentration: total Hb) was measured in the scapular region of the bilateral shoulders using a deep hemodynamics measurement system (PSA-IIIN, Biomedical Science), and its relationship with the severity of the subjective estimation of stiff shoulders (5-grade rating) and that of palpation (4-grade rating) was evaluated. Deep hemodynamic values were affected by the body mass index (BMI) that is highly correlated with subcutaneous fat thickness. Therefore, analysis was performed in 70 patients and 8 healthy volunteers with BMI of 20-24 that does not affect hemodynamic values. Compared with the healthy volunteers, patients who reported marked shoulder stiffness showed a significant decrease in total Hb, and that who reported shoulder stiffness showed a significant decrease in StO₂. On the other hand, compared with the healthy volunteers, patients with marked shoulder stiffness observed by palpation showed significant decreases in both StO₂ and total Hb; the decreases were more marked with more marked stiffness. These results suggested that deep hemodynamics is a diagnostic parameter of stiff shoulders.

Identification of Metronidazole Tablets by Infrared Spectrophotometry / 中国药房

OBEJECTIVE:To establish a rapid and exclusive method for the identification of metronidazole tablets.METHODS:The infrared spectrophotometry was adopted,in which the recrystallization was carried out with the dehydrated alcohol as the solvent and with the highly pure potassium bromide tabletting as the infrared absorption spectrum.RESULTS:The infrared absorption spectrum of the metronidazole tablets was completely in conformity with that of the control substance and the standard spectrum of metronidazole issued in Infrared Spectrum Album of Drugs by State Pharmacopoeia Committee.CONCLUSION:This method is specific,fast and accurate,which can be used for the identification of metronidazole prepa-rations.

Analysis of Gallstone from a Hundred Consecutive Patients with Gallbladder Stone

The gallstones from one hundred consecutive patients having stones in the gallbladder only were analyzed using both gross appearance and infrared spectrophotometry. There were 47 males and 53 females, and the sex ratio was 1:1.13. The most prevalent age was in the fifties in both sexes. Grossly, the number (and also the percentage) of cases of pure cholesterol, mixed cholesterol, calcium bilirubinate, black pigment, and combination stones were 4, 42, 23, 30, and 1, respectively. In the analysis by infrared spectrophotometry, the number of cases of cholesterol, calcium bilirubinate, and calcium carbonate stones were 44, 42, and 14, respectively. The accordance of gross appearance with infrared spectrophotometric classification was statistically significant (p=0.049). A comparison of cholesterol stones with pigment stones showed no difference based on either the sex or the age distribution, but there was a significant difference not only in terms of color, shape, and cut-surface (p=0.000) but also in terms of the number of stones (p=0.045). In conclusion, gallstone classification by gross appearance may be a rapid and relatively accurate method. Further study to standardize gallstone classification by various analytic methods is recommanded.

Quantitative Analysis of Quartz, Mica, and Feldspar in Respirable Coalmine Dust in Taebaek Area by Fourier Transform Infrared Spectrophotometry / 예방의학회지

A Fourier transform infrared spectrophotometric method was described for the determination of quartz, mica(sericite) and feldspar(potassium feldspar) in respirable dust in Taebaek area. The results were as follows; 1) The concentration of minerals were determined from the intensity of absorption peak of quartz at 799 cm-1, sericite at 539 cm-1, and potassium feldspar at 648 cm-1 respectively. 2) The precision(C. V. %) for the quartz determination was 7.70+/-2.68 % from 10 to 200 microgram of quartz. 3) The precision for the sericite determination was 16.34+/-6.82 % from 30 to 500 microgram of serictite. 4) The precision for the potassium feldspar determination was 5.28+/-1.74 % from 30 to 500 microgram of potassium feldspar. 5) The concentration of respirable dust in Taebaek area was 4.90+/-3.29 mg/m3(0.4-93.7%), percent quartz was 1.80+/-4.14% (0.01-20.56%), percent sericite was 11.37+/-6.43% (0.00-29.69%), percent potassium feldspar was 8.15 % (n=7, 3.41-19.70%). 6) The difference of respirable coal dust, quartz, and sericite concentration in drilling, coal cutting, hauling and separating was significant respectively (p<0.05).