RESUMO
Objective to observe the clinical curative effect of treating peptic ulcer based on self prepared Shen-Qi-Jian-Wei Decoction. Methods 100 patients suffered peptic ulcer are devided into two groups in random,each for 50. The control group take the western common treatment, the treatment group is based on the control group combination with the Shen-Qi-Jian-Wei decoction made by self.a course of treatment is 50days. Results the total effective power of the control group is 94.0%, the total effective power of the treat group is 72.0%, the total effective power comparision of two groups isobvious,the diffierence has the stastitical meanings.Conclusion the treatment of peptic ulcer based on the Shen-Qi-Jian-Wei decoction made by self is superior to the pure western medicine group.
RESUMO
Objective To investigate the the effect and mechanism of Jian-wei decoction(JWD) on quality of ulcer healing.Methods The rat models of chronic gastric ulcer were induced by acetic acid,the effects of QOUH of JWD on the model of gastric ulcer were observed,the expression of EGFRmRNA of mucosa were measured in situ hybridization.Results JWD could improve the injury of gastric mucosa and increase the expression of EGFRmRNA in the tissue around peptic ulcer(PU).Conclusion JWD increases the expression of EGFRmRNA in the tissue around PU which might be one of possible mechanisms that JWD improves quality of ulcer healing.