RESUMO
[Objective] To explore the relationship between neuroendocrine changes caused by melatonin (MT) hypo-secretion and kidney-in deficiency syvndrome during prepubescence. [Methods] Thirty SD rats after ablactation were randomly divided into normalgroup (group. A), model group (group B) and herbal medicine group (group C, treated with kidney-yin-nourishing ande(?)ficiency-fire-clearing herbs). Rats in groups B and C were exposed to light continuously for 30 days and simultaneously groupC was given kidney-yin-nourishing and deficiency-fire-clearing herbal medicine (13.3 g?kg-1?d-1, qd) for 30 days . After treatment, blood samples were collected at 0:00-2:00 o'clock to observe the changes of blood MT, testosterone (T), epinephrine (E) and norepinephrine (NE) levels. [Results] Body weight and blood MT level decreased, and T, NE and E levels increased in group A (P