A MULTIVARIABLE ANALYSIS OF HAIR TRACE ELEMENT CONTENTS IN CHILDREN WITH KESHAN DISEASE IN DALI COUNTY YUNNAN PROVINCE / 营养学报

This article presents a discriminant equation for distinguishing children with Keshan disease from normals. The stepwise regressive discriminant equation is established by means of 10 variables including sex, age, and eight-element contents in hair based on 23 patients and 23 normal subjects. Variables finally entered to the discriminant equation are Mn, Cu, Zn, Ca, sex, and age as follows;Y = - 0.89 + 0.09XCu + O.OlXAn- 0.23XMn + 0.48XCa + 0.38Xsex- 0.05XageBy resubstitution test 95.7% accuracy is obtained. Applying the equation to the population (n=247) of endemic and non-endemic area, the accuracy of non-endemic is 100%. Thus, the equation may provide a basis for predicting endemic area or patients with Keshan disease.