A new tetrahydrofuranoid lignan from Genkwa Flos / 中草药

Objective: To study the secondary metabolites of Genkwa Flos (the buds of Daphne genkwa). Methods: The compounds were separated and purified by silica gel chromatography and thin layer chromatography, and their structures were determined by analyses of the physicochemical properties and spectral data. Results: Three lignans were obtained and identified as lariciresinol- 9-O-pentatriacontanoate (1), pinoresinol (2), 4-hydroxysesamin (3) from the ethanol extract of D. genkwa. Conclusion: Compound 1 is a new tetrahydrofuranoid lignan, and known compound 3 is obtained for the first time from this plant.