Koyré no laboratório do Dr. Jacques Lacan / Koyré in Dr. Jacques Lacan's laboratory

Resumo: No presente artigo, buscamos reconstruir o diálogo entre Lacan e Koyré, ocorrido no seminário de 1954-1955, sobre o texto Mênon, de Platão. Infelizmente, não existe gravação da aula, ficamos apenas com algumas discussões que foram retomadas durante os seminários abertos. Contudo, Koyré publicou o seu Introdução à leitura de Platão, no qual um dos capítulos é dedicado especificamente ao texto. Como sustentamos nesse artigo, sua interpretação do texto platônico explica porque Lacan abordava o tema da resistência em análise, comparando os analistas de sua geração com o personagem Mênon.

Abstract: In the present article, we seek to reconstruct the dialogue between Lacan and Koyré, which took place in the 1954-1955 seminar, over Plato's Meno. Unfortunately, there is no recording of the class, we are only left with some discussions that were taken up during the open seminars. Nonetheless, in his book Discovering Plato, Koyré devoted one of the chapters precisely to this text. As we have discussed in this work, his interpretation of the platonic text explains why Lacan approached the theme of resistance in analysis, comparing the analysts of his generation to the character Meno.

THE INHIBITORY EFFECTS OF NIMODIPINE IN ISOLATED GUINEA PIG LEFT ATRIUM AND THIER MECHANISM OF ACTIONS / 中国药理学通报

Fifteen min after adding nimodipine 50 ?mol/L, the contractility of the left atrial muscle decreased from 100 % of control to 55.5 +4.2 o/o and its inhibitory effect was equal to the effect of verapamil (25 ?mol/L ) . Nim at the same concentration inhibited strongly the positive staircase phenomenon but could not reverse it into the negative staircase phenomenon as verapamil 25 ?mol/L did. The same concentration of Nim suppressed significantly the post rest contraction. On the contrary, the post rest contraction was not affected by verapamil at 25 ?mol/L. In addition, Nim 50 ?mol/L reversed or prevented significantly the ouabain-induced arrhythmias in isolated left atria. These results suggest that the negative ino-trbpism of Nim may be related not only to the inhibition of Ca2 + influx to the cells and also to the decrease of the intercellular Ca2+ release and that Nim might present the possibility in treating arrhythmias or other heart disease