Design and Implementation of Medical Equipment Rational Deployment Information System Based on ASP.NET / 中国医疗器械杂志

Based on ASP.NET framework, The Intelligent Estimated System for Rational Deployment of Medical Equipment (MERDIS) is designed and developed with SQL Server 2012 database and C# language. The system is used to realize the rational deployment suggestions and evaluation of medical equipment in hospitals. The system input the data of hospital medical equipment and clinical pathway into the database, and then feedback the deployment information to users which are calculated by big data information, so as to achieve the purpose of giving rational deployment of hospital medical equipment.

Neural Adaptation Analysis of Muscle Isometric Maximum Voluntary Contraction Resistance Training at Different Joint Angles / 医用生物力学

Objective To study the characteristics of neural adaptation for resistance training of maximum voluntary contraction (MVC) of muscles at different joint angles. Methods Thirty healthy male college students were randomly divided into 3 groups, and each group was subjected to MVC isometric contraction resistance training at elbow joint angles of 45°, 90°, and 135°. Surface electromyography (sEMG) signals of the biceps brachii were measured before and after training, and the root mean square (RMS) and median frequency (MF) of the sEMG signals were also analyzed. ResultsThere were significant differences in normalized RMS of sEMG for the biceps brachii before and after training at 45°, 90°, and 135° elbow joints. Comparison of the RMS between different angles after training showed that 45° was significantly different from 90° and 135°. There were no significant differences between 90° and 135°. After training, no significant differences were found in normalized MF at all angles. Conclusions The RMS of sEMG shows angle-specific changes, while the MF of sEMG does not have angle-specific changes. When the biceps brachii is at the middle and large elbow joint angles, the neural adaptation effect produced by isometric resistance training is better.

Evaluation on central and peripheral origin of muscle fatigue / 医用生物力学

atigue is a common phenomenon in many medical and neurologic diseases. Understanding the origins of fatigue in these diseases is of great guiding significance in developing targeted interventions for muscle fatigue. In this review, the central origin (including all the supraspinal and spinal physiological phenomena capable of inducing a decrease in motoneuron excitation) and the peripheral origin (including neuromuscular transmission, propagation of action potentials in muscle, excitation-contraction coupling) of muscle fatigue were summarized. The methods of assessing the central or peripheral origin of muscle fatigue were discussed, including the direct measurement (maximal voluntary contraction force, twitch force) and the indirect tests (twitch interpolation, electromyography, motor cortical stimulation).

ELECTROMYOGRAM PATTERNS DURING SUSTAINED LOW-LEVEL PLANTAR FLEXIONS AND CHANGES IN BLOOD FLOW FOR "ALTERNATE ACTIVITY" AMONG THE TRICEPS SURAE MUSCLES / 体力科学

Several studies have described "Alternate activity", in which individual muscles of the synergistic muscle group alternate between high activity and silent periods, and rotate in a complementary pattern to maintain constant torque, during sustained low-level contractions. The purpose of this study was to investigate the physiological property of alternate activity among the synergists. Eight human subjects performed static contractions at an ankle joint angle of 110° plantar flexion at 10% maximal voluntary contraction (MVC) for 120 min. Simultaneously, a surface electromyogram (EMG) was recorded of the triceps surae muscles. Doppler ultrasound techniques were used to measure blood velocity and the arterial diameter of the popliteal artery during exercise. Maximal torque at MVC and mean EMG (mEMG) level decreased significantly after sustained isometric low-level contractions, but there was no significant difference in the mEMG/maximal force ratio of triceps surae muscles, which is thought to indicate peripheral fatigue between pre- and post-exercise. Throughout the "Alternate activity", arterial diameter and pulse rate did not change, but blood flow significantly increased (p<0.001) depending on an increase in blood velocity. These results suggest that "Alternate activity" among the triceps surae muscles may be one mechanism that functions either to decrease or to postpone peripheral fatigue during sustained low-level contraction.

A New Efficient Cryopreservation of Human Embryonic Stem Cells by a Minimum Volume Cooling Method / 대한불임학회지

No abstract available.

Correlation between Tumor Angiogenesis and Metastasis in Invasive Breast Carcinoma

Tumor angiogenesis(TA) refers to the growth of new vessels toward and within a tumor. TA is necessary both at the beginning and at the end of the metastatic cascade of events. Recently, experimental evidence suggests that the growth of a tumor beyond a certain size requires angiogenesis. To investigate how tumor angiogenesis correlates with metastases in breast carcinoma, the microvessels were counted (per 200 / field) in the most active areas of neovas-cularization by two investigators. The microvessels within breast carcinoma were highlighted by in imunohistochemical staining for factor VIII-related antigen. Microvessel count(MVC) in node-positive carcinoma(59.66=35) was significantly higher than in node-negative carcinoma(44.76=17)(p=0.009). MVC was also statistically correlated with tumor size and stage, but not with histologic grading, DNA ploidy, or hormonal receptors(estro-gen and progesterone). MVC in invasive breast carcinoma may be one of many prognostic predictors of node-positive breast carcinoma. Assessment of tumor angiogenesis may therefore be valuable in selecting patients with early breast carcinoma for aggressive therapy.

Construction of PACS in Muti-layer Structure / 医疗卫生装备

Objective To improve the efficiency,repeatability,expansibility and maintainability and reduce the construction and maintenance cost of the PACS.Methods Struts and Hibernate frame works based on MVC and Object-Oriented Analysis(OOA) were used to build PACS.Results It saved more time for developers,and promoted the development efficiency.Conclusion It is rapid and efficient to use Struts and Hibernate frame in building PACS.[Chinese Medical Equipment Journal,2008,29(2):55-57]