A Review on Anti-Diabetic Herbs of Siddha System Based on Their Organoleptic Characteristic

The Siddha system is a primordial system of medicine followed over a long period in the Southern part of India. Siddha system has peculiar methods in treating a disease and also possesses various diagnostic methods and treatment protocols. In the Siddha system, diagnostic methods are purely differing from other systems. The diagnostic tools are Envagaithervu (Eight Fold Assessment Test), Neer Kuri & Nei Kuri (Siddha Urine Test), Nadi (Pulse Test) etc. In the Siddha system treatments are based on Nadi, Suvai. Diabetics are the major non-communicable disease in the world. According to the statistics India is second among the top ten nations in the world, with 69.2 million people suffering from diabetes and another 36.5 million struggling with pre-diabetes. This rising prevalence is mostly due to changes in lifestyle, such as consuming unhealthy foods and being physically sedentary. In the Siddha system, it is compared with Neerizhuvu Noi. In Siddha, diabetes is not an illness. It is possible to keep it under control with the right diet and treatment. The article focus on scientific justification of the relationship of herbs cured Neerizhuvu Noi mentioned in classical text by their organoleptic characters and anti diabetic activity of the herbs. Taste plays a significant part in the selection of medicinal plants for each person in this kind of personalized treatment that is based on their constitution. This article discusses the Siddha approach to the control of diabetes, with a particular focus on the flavour of herbs.

Metabolic Syndrome In Madhumegam (type 2 Diabetes Mellitus) Patients Reporting At National Institute Of Siddha – A Cross Sectional Study

Introduction: Madhumegam is a clinical condition characterised by frequent and excessive urination which ultimately leads to deterioration of seven body constituents and three humours. Its signs and symptoms may be correlated with Diabetes mellitus in modern science. Since, metabolic syndrome has become major cause of morbidity and mortality, identifying its cause and prevention has gained immense importance. Aim: This study aimed at determining the prevalence of metabolic syndrome in Madhumegam (Type 2 Diabetes mellitus) patients and to identify the most critical predictive risk factors of metabolic syndrome. Methods: This hospital based cross sectional study involved 100 type 2 diabetes mellitus patients and was conducted at Ayothidoss Pandithar Hospital, National Institute of Siddha. This study used questionnaire to obtain information on diabetic condition, anthropometric measurements and lipid profile. Metabolic syndrome was defined according to the International Diabetes Federation criteria. Results: The prevalence of metabolic syndrome was 53% in the study population. Elevated triglyceride was the commonest component (77.3%) followed by lowered HDL (51%). Female type 2 diabetic patients had a higher prevalence of metabolic syndrome (54.7%) than their male counterparts (45.3%). With respect to age, individual within the age group of 60-69 had highest prevalence of metabolic syndrome while age group of 30-39 has least prevalence of metabolic syndrome. Conclusion: Elevated triglyceride for men and lowered HDL for women were the strongest risk factors. Metabolic syndrome is a significant health problem and its preventive strategies should focus on early diagnoses and lifestyle modification.

A Drug Review On Efficacy Of ‘pereechangai Nei’ A Classical Siddha Drug In The Management Of Madhumegam (type 2 Diabetes Mellitus)

In Siddha system of medicine, diseases are classified into 4448 types. According to Yugi Vaithiya Chinthaamani, a siddha classical text Meganoi is classified into 20 types based on three humors Vatha, Pitha, Kabha. Madhumegam is one among them, which comes under Pitha type called Thithippu Neer. The causes, signs and symptoms of Madhumegam could be correlated with Diabetes Mellitus in modern system. Mathumegam is a clinical condition characterized by frequent and excessive passage of urine with ‘sweetness’ eventually leading to deterioration of seven body constituents. Its deterioration causes Avathaigal which are described as complications of long term poorly controlled hyperglycemia. Diabetes mellitus is one of the major health problems in most developing countries. Being a lifestyle disorder its management is still a challenge for modern system of medicine. Increase in the number of diabetic patients, high cost for medical treatments, unsatisfactory treatment response are the major reasons for people to switch over to traditional medicinal systems. At current scenario, Siddha system among Indian systems of medicine is gaining more attention globally and it serves as a hope in controlling this dreadful disease and preventing its high risk complications. Siddha drugs include herbal, mineral and herbo-mineral drugs. Among which pure herbal medicines serve the purpose in the management of chronic diseases like Madhumegam for long term use. This review article focuses on one such polyherbal Siddha formulation ‘Pereechangai nei’ as mentioned in text Therayar Maha Karisal, specifically indicated for Madhumegam.

Clinical Evaluation Of A Siddha Poly Herbal Formulation Azhinjiyathikashayam In Madhumegam (type €“ 2 Diabetes) Patients

Azhinjiathikashayam is a herbo mineral Siddha poly herbal formulation said for the management of Madhumegam (Type-2 Diabetes mellitus) in ancient Siddha literature. The study drug was subjected to estimate the therapeutic efficacy in Madhumegam patients. A well designed study protocol was approve by Institutional Ethics Committee and the clinical study was conducted as an open clinical trial in OPD/IPD of Ayothidoss pandithar Hospital of National Institute of Siddha Chennai. Based on the inclusion criteria 40 Madhumegam patients (Type -2 Diabetes mellitus) were enrolled in this study. Informed consent was obtained from each patient before study initiation. 60ml of Azhinjiathikashayam was administered orally before food twice a day for a period of 90 days and advised to follow the prescribed dietary regimen. All the baseline data, Laboratory investigations were recorded in the prescribed Case Report Form of each patient. Blood sugar level in fasting and postprandial was done once in 30 days and HbA1c was done before treatment (0th day) and after treatment (90th day). The clinical assessment was recorded once in 10 days. Paired ‘t’ test was used to test the significance of treatment using before and after treatment data on HbA1c, Clinical symptoms, Blood sugar fasting and postprandial. The level of significance probability 0.05 was used to test the treatment difference and the values are statistically significant. In this study there is statistically significant difference between before and after treatment on average HbA1c, average blood sugar of fasting and average clinical feature score (p < 0.0001).