Clinico-Mycological study of dermatophytosis in and around Kakinada.

Background: Dermatophytosis is a clinical condition caused by a fungal infection of the skin in humans and domesticated animals. Currently up to 20% of the population may be infected by one of the dermatophytes. Objective: To isolate and identify the fungal agents from clinical samples of dermatophytosis patients in and around kakinada. Materials and Methods: Clinical samples from 150 patients were subjected to potassium hydroxide (KOH) examination and culture. Causative organisms are identified macroscopically and microscopically. Statistical analysis was done by chi square test. Results: Out of 150 samples, 120 shown KOH positive and 66/120 (55%) samples were culture positive. Of these isolation rate of dermatophytes was 70/120 (58.3%) among these, 66 were Trichophyton species, 3 were Microsporum species, 1 was Epidermophyton floccosum. T.rubrum was the major isolate about 35(29.1%) strains. The male to female ratio of the positive cases was recorded as 11:3. The most effected age group was 21-30years (40%) followed by 31-40 years (28.6%). Conclusion: It may concluded from the present study that Tinea corporis is more frequently encountered condition followed by Tinea cruris. T.rubrum was implicated as major predominating species followed by T.mentagrophytes. Unhygienic conditions among low socioeconomic group, frequent migration of laborers, workers, hot and humid climatic conditions may be some of the contributing epidemiological factors. The study signifies the importance of mycological examination of dermatophytoses samples for effective management and also for epidemiological studies.

Evaluation of therapeutic efficacy of medical shampoo containing terbinafine hydrochloride and chlorhexidine in dogs with dermatophytosis complicated with bacterial infection / 동물의과학연구지

This study evaluated the efficacy and safety of medical shampoo containing terbinafine hydrochloride and chlorhexidine gluconate in dogs with dermatophytos is complicated with bacterial infection. Although several studies in dogs and cats with fungal dermatitis have found that oral administration of terbinafine is effective for controlling clinical signs, the topical form of terbinafine has rarely been studied in dogs and cats. Therefore, this study evaluated the efficacy of medical shampoo containing terbinafine hydrochloride and chlorhexidine gluconate in dogs with dermatophytos is complicated with bacterial infection. Eight dogs infected with Microsporum spp. complicated with bacterial infection were enrolled in this study. These dogs were further blindly divided into Group 1 (no treatment, fourdogs) and group 2 (treated with medical shampoo with terbinafine/chlorhexidine, four dogs). Clinical improvement was evaluated using bacterial and fungal cultural evaluation combined with clinical evaluation. This study found that the medical shampoo has sufficient efficacy to treat varying degrees of dermatophytosis complicated with bacterial infection in dogs, although the speed of improvement differed according to the degree and type of infection. Our study also found that combined therapy using antifungal and antibacterial agents can improve clinical signs more effectively and rapidly, suggesting that concurrent bacterial infection plays a significant role in the development of dermatitis.

Epidemiologia e etiologia das dermatofitoses em Pernambuco 2005-2010 / Epidemiology and etiology of the dermatophytosis in Pernambuco, 2005-2010

A presente pesquisa teve como objetivos detectar, isolar e identificar espéciesdermatófitos em amostras de pele, pêlos e unhas de 5.590 pacientes oriundos de hospitais públicos de Pernambuco. Os resultados apontaram o Trichophyton rubrum como a espécie de dermatófito mais incidente. O gênero masculino e faixa etária entre 0-20 anos prevaleceram...

Epidemiologia, etiologia e formas clínicas das dermatofitoses em Pernambuco, 1995-2005 / Epidemiology, etiology and clinical presentation of dermatophytosis in Pernambuco, 1995-2005

Num total de 1.238 casos de dermatofitoses, ocorridas na Cidade de Recife /PE, observou-se predomínio das tinhas de couro cabeludo (33,7 por cento) e Trichophyton tonsurans (25,5 por cento), entre 1995 e 1999, enquanto as tinhas de pele glabra (35,5 por cento) e Trichophyton rubrum (34 por cento) foram mais freqüentes entre 2000 e 2005. Detectou-se importante redução do Trichophyton mentagrophytes, no último período.

Out of a total of 1,238 cases of dermatophytosis in the city of Recife (Pernambuco), lesions of the scalp (33.7 percent) and Trichophyton tonsurans (25.5 percent) predominated between 1995 and 2000, while lesions of the hairless skin (35.5 percent) and Trichophyton rubrum (34 percent) were the most frequent between 2000 and 2005. A significant reduction in Trichophyton mentagrophytes was detected in the second of these periods.