Analysis of the current status and related factors of first aid knowledge among middle-aged and elderly residents in a community in Shanghai / 上海预防医学

ObjectiveTo investigate the current status of first aid knowledge among middle-aged and elderly residents aged 50 and above in a community in Shanghai， in order to provide reference for improving the self-rescue and mutual aid capabilities of middle-aged and elderly residents. MethodsA multi-stage stratified random sampling method was used to conduct a survey on 335 residents aged 50 and above in a community in Shanghai using a self-made survey questionnaire. The current situation and related factors of emergency knowledge level of residents aged 50 and above in the community were comprehensively analyzed. ResultsFirst aid knowledge level of 335 residents aged 50 and above was low， and the rate of high cognitive level was only 24.18%. Univariate analysis showed that male residents had a higher awareness rate than female residents （P=0.044）， while residents aged 70 and above and 60‒ had lower awareness rates than residents aged 50‒ （P<0.05）. Residents with chronic diseases had a higher awareness rate than those who did not （P=0.031）. Residents with family members suffering from chronic diseases had a higher awareness rate than those without （P<0.001）. Experience of first aid training affected residents’ awareness of first aid （P=0.003）. ConclusionThe level of first aid knowledge among middle-aged and elderly residents aged 50 and above in the community is low. Age， the presence of chronic diseases in family members， and emergency training are independent and relevant factors that affect the awareness of first aid knowledge among middle-aged and elderly residents. The government and relevant institutions should explore the establishment of a standardized emergency response training system， implement classification and grading for middle-aged and elderly groups with different characteristics， and provide targeted emergency training to strengthen their self-rescue and mutual aid capabilities and improve the success rate of pre-hospital emergency care.

Mediating effect of negative emotions on visual impairment and resilience among middle-aged and elderly populations / 预防医学

Objective @#To investigate the mediating effect of negative emotions on visual impairment and resilience among middle-aged and elderly populations, so as to provide insights into improving psychological health among middle-aged and elderly populations.@*Methods@#Demographic information, visual impairment, negative emotions and resilience in the residents at ages of 45 years and older were collected through the database of the Yushu Physical and Mental Health Survey carried out by Institute of Psychology of Chinese Academy of Sciences. Structural equation model was used to analyze the effects of visual impairment and resilience and the mediating role of negative emotions. @*Results@#Totally 2 997 middle-aged and elderly populations were enrolled, with the median age of 50.00 (interquartile range, 47.00) years. There were 1 320 males (44.04%) and 1 677 females (55.96%), 1 627 illiterate persons (54.29%), and 2 780 married persons (92.76%). The scores of visual impairment, negative emotions and resilience were (6.79±2.59), (6.35±3.05) and (33.38±10.41) points, respectively. The results of structural equation model analysis showed that after adjusting for age, gender, educational level and marital status, visual impairment had a direct negative positive effect on resilience, with a direct effect value of -0.157 (95%CI: -0.177 to -0.137), and visual impairment could also negatively affect residence through negative emotions, with a mediating effect value of -0.112 (95%CI: -0.126 to -0.104), and the mediating effect contributed 41.64% to the total effect.@*Conclusion@#visual impairment could reduce residence directly or indirectly through the mediating effect of negative emotions among middle-aged and elderly populations.

Retrospective cohort study on the factors influencing poor prognosis in young and middle-aged patients with pulmonary tuberculosis / 公共卫生与预防医学

Objective To conduct a retrospective cohort study on the influencing factors of poor prognosis of young and middle-aged patients with pulmonary tuberculosis. Methods Selecting 426 young and middle-aged patients who were diagnosed with pulmonary tuberculosis in our hospital from January to December 2018 as the research subjects. Collecting the social demography information of all patients and the information of potential factors affecting the prognosis (allergy history, smoking history, drinking history, BMI level, disease information, treatment information, etc.) and discussing the factors affecting the prognosis of young and middle-aged pulmonary tuberculosis patients and their effects. Results The average age of 426 patients was (41.93±5.17) years old, the average BMI of them was (21.97±3.15) kg/m2, and an average course of disease of them was (2.76±0.99) years. There was no significant difference in the basic sexual information between men and women. In this study, a total of 128 patients with poor prognosis were retrospectively followed up, including 90 males and 38 females. The detection rate of males was significantly higher than that of females (χ2=16.976, P2=18.850, P2=38.924, P2=127.207, P2=32.566, P2=16.715, P2=17.315, P2=16.976，P1 and P1 and P<0.05; Regular treatment still showed potential protective factors, with an HR of 0.408, P<0.05. Conclusion: Male, emaciated body type, disease course ≥ 5 years, smoking history, number of lung field lesions ≥ 3, presence of pulmonary cavities and comorbidities are potential risk factors, while regular treatment suggests potential protective factors. Conclusion More targeted disease control and management should be implemented for middle-aged and young patients with pulmonary tuberculosis based on the aforementioned influencing factors to improve their prognosis.

Association between skeletal muscle mass and metabolic syndrome in middle-aged and elderly community residents / 上海预防医学

ObjectiveTo explore the correlation between skeletal muscle mass and metabolic syndrome （MS） disease risk among middle-aged and elderly community residents in Urumqi， and to provide a theoretical basis for understanding the relationship between skeletal muscle mass and MS among middle-aged and elderly community residents in China. MethodsA total of 1 438 community residents ≥ 50 years old were selected as the research subjects from July 2018 to January 2019 in Urumqi. They were selected from a multi-ethnic natural population cohort in Xinjiang. Data were collected through questionnaires， physical examination， bioelectrical impedance analysis （BIA）， laboratory tests， etc. Skeletal muscle mass was evaluated using the limb skeletal muscle mass index （SMI） corrected for body weight； MS was defined as it at least includes three of the following： abdominal obesity， hypertension， hyperglycemia， high triglycerides and low high-density lipoprotein cholesterol. SMI was divided into four quantile arrays of Q1‒Q4. Trend χ2 test was applied to explore whether there was a correlation between SMI changes and MS. A multivariate logistic regression model was used to analyze whether there is a difference in the risk of MS between the higher SMI group （Q2， Q3， Q4） and the reference group Q1. ResultA total of 560 MS patients were detected in this study， with a prevalence rate of 38.94%. Among them， the prevalence rate of MS was 39.16% in males and 38.80% in females. The increase in male SMI grading level is not correlated with the prevalence of MS （trend P>0.05）； After adjusting for confounding factors （model 4）， the increase in SMI was still not related to the prevalence of MS （Ptrend=0.995）. There was no statistical difference in the risk of MS between the lowest quartile group Q1 and the highest quartile group Q4 （OR=1.01， 95%CI： 0.69‒1.78）. The prevalence of MS in women gradually decreased with the increase of SMI grading level （Ptrend<0.001）； After adjusting for confounding factors （model 4）， there was still a correlation between the increase of SMI and the prevalence of MS （Ptrend=0.005）. With the lowest quartile of SMI Q1 as the reference group， the risk of MS in Q2 （OR=0.63， 95%CI： 0.40‒1.00）， Q3 （OR=0.56， 95%CI： 0.34‒0.94）， Q4 （OR=0.42， 95%CI： 0.23‒0.76） decreased. ConclusionAn increase in skeletal muscle mass may be beneficial for preventing MS， especially among middle-aged and elderly female residents. Considering the intensification of aging in China and the close relationship between MS and related comorbidities， managing skeletal muscle mass may contribute to potential MS prevention.

Work and lifestyle influencing factors for thyroid cancer among young and middle-aged patients with thyroid nodules / 环境与职业医学

Background The number of persons with thyroid nodules has increased rapidly in recent years, and thyroid cancer caused by malignant nodules has become a key problem endangering the health of young and middle-aged groups in China. Objective To explore work and lifestyle influencing factors for developing thyroid cancer among young and middle-aged patients with thyroid nodules. Methods The subjects with thyroid nodules were reported by routine physical examines ordered at the Huadong Sanatorium. We conducted a 1∶4 matched case-control study in which 232 patients diagnosed with thyroid cancer from 2012 to 2022 were matched to 928 controls by gender and age (±5 years). A validated questionnaire was used to collect data on work and lifestyle behaviors. Univariate and multivariate logistic regression models were applied to explore potential relationships between selected factors (including environment, working hours, stress, diet, exercise, and mental health) and thyroid cancer. Spearman rank correlation was used to analyze the correlations between variables. Results The results of univariate logistic regression showed a history of thyroid cancer reported among first-degree relatives (OR=6.059, 95%CI: 1.007, 36.473), obesity (OR=1.973, 95%CI: 1.296, 3.004), noise and vibration exposure (OR=1.988, 95%CI: 1.143, 3.456), frequent stress (OR=2.093, 95%CI: 1.231, 3.559), frequent depression (OR=2.034, 95%CI: 1.048, 3.947), frequent anger (OR=1.791, 95%CI: 1.066, 3.012), frequent fried food diet (OR=1.535, 95%CI: 1.026, 2.297), and frequent fast food diet (OR=1.836, 95%CI: 1.048, 3.215) were risk factors for reporting thyroid cancer developing from thyroid nodules, while regular meals (OR=0.245, 95%CI: 0.061, 0.989) and frequent exercise (OR=0.571, 95%CI: 0.342, 0.952) were protective factors for reporting no thyroid cancer. The results of Spearman correlation analysis showed that body mass index was positively correlated with frequent fried food, fast food, and sugary beverage diets (r=0.123, 0.083, 0.077, P<0.01), and negatively correlated with frequent depression and anger (r=−0.090, −0.070, P<0.05). The results of multiple logistic regression found that a history of thyroid cancer reported among first-degree relatives (OR=6.712, 95%CI: 1.071, 42.066), obesity (OR=2.032, 95%CI: 1.321, 3.125), noise and vibration exposure (OR=1.991, 95%CI: 1.089, 3.637), and frequent stress (OR=2.468, 95%CI: 1.417, 4.300) were associated with an elevated risk of reporting thyroid cancer developing from thyroid nodules patients. Regular exercise (frequency≥3 times·week−1, > 30 min per episode) (OR=0.516, 95%CI: 0.300, 0.890) was associated with a lowered risk of reporting thyroid cancer. Conclusions Multiple risk factors associated with reporting thyroid cancer among young and middle-aged groups with thyroid nodules are identified, such as obesity, noise and vibration exposure, frequent stress, and lack of exercise.

Validation of the Scale of Perceived Risk of Sexually Transmitted Infections in Middle-aged and Older Adults

Background: Middle-aged and older adults often mistakenly underestimate the risk to which they are exposed when they engage in risky sexual behaviors. Furthermore, a reliable and valid measurement of the construct is necessary to capture its scope and meaning. Objective: To validate the structure of the Perceived Risk Scale for STIs in middle-aged and older adults, identify their perceived risk of STIs, and identify their relationship with some sociodemographic characteristics. Methods: The sample was composed of 295 middle-aged and older adults. A virtual online sampling was used. Males and females aged 50 years and older, sexually active in the last 12 months, were included. To measure the perceived risk of STIs, the scale of perceived risk for human immunodeficiency virus (HIV) was adapted, and a confirmatory factor analysis of the proposed three-factor structure was carried out. Results: The proposed structure of the scale was found to present acceptable adjustment rates (X 2= 48.283, p <.001; CFI = .962, RMSEA = .079, GFI = .963, TLI = .938). 28.1% of the participants presented low perceived risk; 46.8%, medium perceived risk; and 25.1%, high perceived risk. Association between marital status and perceived risk of STIs was identified. Conclusion: The Perceived Risk Scale for STIs is a reliable and valid instrument for capturing perceived risk of STIs in middle-aged and older adults. An appropriate measurement is considered important to accurately examine the relationship between perceived risk and behavior.

Antecedentes: Los adultos de mediana y tercera edad suelen subestimar erróneamente el riesgo al que se exponen cuando realizan conductas sexuales de riesgo, además, es necesaria una medición fiable y válida del constructo para captar su alcance y significado. Objetivo: Validar la estructura de la Escala de Riesgo Percibido a las ITS en adultos de mediana y tercera, identificar su riesgo percibido a las ITS e identificar su relación con algunas características sociodemográficas. Métodos: La muestra estuvo compuesta por 295 adultos de mediana y tercera edad. Se utilizó un muestreo virtual en línea. Se incluyeron hombres y mujeres de 50 años o más, se-xualmente activos en los últimos 12 meses. Para medir el riesgo percibido a las ITS se adaptó la escala de riesgo percibido al Virus de Inmunodeficiencia Humana (VIH) y se realizó un análisis factorial confirmatorio de la estructura propuesta conformada por tres factores. Resultados: Se comprobó que la estructura propuesta de la escala presentaba mostró índices de ajuste aceptables (X2 = 48.283, p <.001; CFI = .962, RMSEA = .079, GFI = .963, TLI = .938). El 28.1% de los participantes presentó un riesgo percibido bajo, el 46.8% un riesgo percibido medio y el 25.1% un riesgo percibido alto. Se identificó la asociación entre el estado civil y el riesgo percibido de ITS. Conclusiones: La Escala de Riesgo Percibido de ITS es un instrumento fiable y válido para captar el riesgo percibido a las ITS en adultos de mediana y tercera edad. Se considera importante una medición adecuada para examinar con precisión la relación entre el riesgo percibido y la conducta.

Association of Dietary and Physical Activity Patterns and Hypertension in Western Rajasthan, 2022

Introduction: Hypertension (HTN) is a modifiable risk factor for coronary artery disease, heart failure, cerebrovascular disease and chronic renal failure. HTN affects about 1 billion people globally; by 2025, up to 1.58 billion adults worldwide are likely to suffer from complications of HTN. This study was done to know the diet and physical activity patterns and HTN among the population of three districts of Western Rajasthan. Objectives: To study the dietary and physical activity patterns among the population of Western Rajasthan. and to compare key findings among three districts Pali, Jodhpur and Barmer so that lifestyle changes can be recommended. Methods: A case-control study was done among attendees of NCD clinics of tertiary-level centers in Pali, Barmer and Jodhpur. Hospital Controls were matched to age (± 5 years) and gender Considering the prevalence of HTN to be 20%*, the proportion of exposure in the general population as 0.2, odds ratio to be 2.2, power =80%, alpha=5% sample size is estimated to be 102 cases & 102 controls (from each district). Results: Overall being married (OR= 3.3), having diabetes Cardiac disease (OR= 2.6), excessive salt consumption (OR= 2.7), moderate physical exercise less than 30 minutes (OR=1.9), using oil other than vegetable oil(OR=1.8) , Age >?60 years (OR =1.4) were the key risk factors. It was found that high BMI (BMI>27), consumption of non-vegetable oils (12.7%) was highest in Jodhpur, lack of moderate exercise for at least 30 minutes (81%), lack of sports activity (92%) was highest in Pali, least number of days/week of fruits and vegetables consumption (~1.64 days) was seen in Barmer. Conclusions: Change in quantity of salt consumption and incorporation of moderate physical exercise for >30 minutes was most followed in control of HTN among the attendees of NCD Clinics from the multiple advise given.

A Study of Clinico-social Profile of Animal Bite Patients Attending the Antirabies Clinic of BRD Medical College, Gorakhpur

Background: Rabies is one of zoonotic viral disease, estimated to cause 59000 human deaths annually in over 150 countries, of which 20,000 are from India alone; about 40% of which are in children under the age of 15. Rabies though 100% fatal is preventable with post-exposure prophylaxis which includes wound washing, anti-rabies vaccination and rabies immunoglobulin. Objective: To describe the clinico-social profile of animal bite patients attending the anti-rabies clinic of BRD Medical College, Gorakhpur. Methodology: A cross-sectional study was conducted in the anti-rabies clinic of Nehru hospital, BRD Medical College, Gorakhpur from January 2022 to May 2022. Study participants were interviewed by using a pre-phrased, pre-designed and pre-tested questionnaire. Data regarding socio-demographic and clinical profile of the study participants following animal bite exposure was collected. Results: The total number of animal bite victims were 250, in which majority of them were males (76.77%) and highest percentage was of adult population (20-59 years). Maximum number of victims were from rural area (78.70%). 19.35% were working and 39.35% were students. 77.43% were category III bites and in 50.96% cases lower limb was the site of bite and dogs were responsible for 89.67% of the bites. 60.64% victims did not wash the wound properly before reaching the anti-rabies clinic. Conclusion: This study concludes that as majority of the animal bite victims were students and majority of victims were unaware about the importance of wound care, therefore a step can be taken to create awareness in various schools.

Healthcare Seeking Behaviour of Hospitalised COVID-19 Patients During Second Wave in Tertiary Care Hospital of Northern India

Background: The Coronavirus Disease (COVID-19) pandemic continues its deadly reign all over the world. Devising effective strategies for detecting and controlling the infection has become ever more critical. Effective prevention and control of the pandemic is entirely dependent on human behavior in terms of practicing preventive and curative measures. During the second wave of COVID-19, people’s perceptions of preventive and curative measures changed. Objective: To study healthcare-seeking behavior of hospitalized COVID-19 patients. Methods: Hospitalized patients due to COVID-19 in the month of March, April and May of 2021 were included in the study. Their attendants/close relatives were contacted telephonically to know about the admitted patients’ healthcare-seeking behavior. Verbal consent was taken from attendants before the commencement of the interview, followed by informing them about the purpose of the interview. Results: Amongst the subjects, there were more males than females (67.5 vs 32.4%), age ranged between 18 to 88 with a mean value of 56.61 ± 14.7 years. Self-medication was significantly associated with study subjects’ mortality (p=0.03). Conclusion: Elderly people were having higher mortality rate than their younger counterparts. People were hesitant to visit primary care physicians after having symptoms of COVID-19.

Effects of resistance exercise on physical health in middle-aged and elderly women / Efeitos do exercício de resistência sobre a saúde física de mulheres de meia-idade e idosas / Efectos del ejercicio de resistencia en la salud física de mujeres de mediana y avanzada edad

ABSTRACT Introduction: Several methods of sports training are applied to improve physical health in middle-aged and elderly women. Among the emerging ones is resistance exercise, despite little evidence about its effects in this population group. Objective: Explore the effects of resistance exercise on promoting muscle health and reducing cardiovascular risk in middle-aged and elderly women. Methods: A questionnaire on the level of muscle health and cardiovascular risk factors of 100 middle-aged and elderly women was conducted. A total of 20 middle-aged and elderly women were randomly selected as participants, and the experimental group performed resistance exercise training, while the control group performed simple exercise training. Results: In the muscle health indicators of the experimental group, BMI decreased by 0.3%, body fat decreased by 1.3%, waist-to-hip ratio decreased by 0.01, fat decreased by 1.7 kg, lean weight increased by 2.8 kg, and protein decreased by 0.9 kg. The changes in cardiovascular health indicators in the experimental group were greater than those in the control group. Conclusion: Resistance exercise can effectively improve muscle health in middle-aged and elderly women, reducing cardiovascular risk. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.

RESUMO Introdução: Diversos métodos de treinamento esportivo são aplicados para melhorar a saúde física de pessoas de meia-idade e idosas. Dentre os emergentes está o exercício de resistência, apesar de pouca evidência sobre seus efeitos neste grupo populacional. Objetivo: Explorar os efeitos do exercício de resistência na promoção da saúde muscular e na redução do risco cardiovascular em pessoas de meia-idade e idosas. Métodos: Foi realizado um questionário sobre o nível de saúde muscular e fatores de risco cardiovascular de 100 mulheres de meia-idade e idosas. Um total de 20 mulheres de meia-idade e idosas foram selecionadas aleatoriamente como participantes, e o grupo experimental realizou treinamento com exercícios resistidos, enquanto o grupo controle realizou treinamento com exercícios simples. Resultados: Nos indicadores de saúde muscular do grupo experimental, o IMC diminuiu 0,3%, a gordura corporal diminuiu 1,3%, a relação cintura/quadril diminuiu 0,01, a gordura diminuiu 1,7 kg, o peso magro aumentou 2,8 kg, e a proteína diminuiu 0,9 kg. As mudanças nos indicadores de saúde cardiovascular no grupo experimental foram maiores do que as do grupo de controle. Conclusão: O exercício de resistência pode efetivamente melhorar a saúde muscular em mulheres de meia-idade e idosas, reduzindo o risco cardiovascular. Nível de evidência II; Estudos terapêuticos - investigação dos resultados do tratamento.

RESUMEN Introducción: Se aplican varios métodos de entrenamiento deportivo para mejorar la salud física de las personas de mediana y avanzada edad. Entre los emergentes se encuentra el ejercicio de resistencia, a pesar de la poca evidencia sobre sus efectos en este grupo poblacional. Objetivo: Explorar los efectos del ejercicio de resistencia en la promoción de la salud muscular y la reducción del riesgo cardiovascular en personas de mediana edad y ancianas. Métodos: Se realizó un cuestionario sobre el nivel de salud muscular y los factores de riesgo cardiovascular de 100 mujeres de mediana edad y ancianas. Un total de 20 mujeres de mediana edad y ancianas fueron seleccionadas aleatoriamente como participantes, y el grupo experimental realizó entrenamiento con ejercicios de resistencia, mientras que el grupo de control realizó entrenamiento con ejercicios simples. Resultados: En los indicadores de salud muscular del grupo experimental, el IMC disminuyó un 0,3%, la grasa corporal disminuyó un 1,3%, la relación cintura-cadera disminuyó un 0,01, la grasa disminuyó 1,7 kg, el peso magro aumentó 2,8 kg y las proteínas disminuyeron 0,9 kg. Los cambios en los indicadores de salud cardiovascular del grupo experimental fueron mayores que los del grupo de control. Conclusión: El ejercicio de resistencia puede mejorar eficazmente la salud muscular en mujeres de mediana y avanzada edad, reduciendo el riesgo cardiovascular. Nivel de evidencia II; Estudios terapéuticos - investigación de los resultados del tratamiento.

Experiencia de cuatro años con la cinta reajustable para incontinencia urinaria de esfuerzo / 4-year experience with the use of readjustable tape for stress urinary incontinence

Resumen OBJETIVO: Describir la experiencia con el cabestrillo reajustable Remeex® en pacientes con incontinencia urinaria de esfuerzo recurrente, como una alternativa de tratamiento. MATERIALES Y MÉTODOS: Estudio retrospectivo, observacional, de serie de casos llevado a cabo en un solo centro de la ciudad de Medellín, Colombia, en pacientes atendidas en la Unidad de Uroginecología de la Clínica Universitaria Bolivariana. Criterios de inclusión: mujeres mayores de 18 años, con diagnóstico de incontinencia urinaria recidivante después de una o más cirugías fallidas para corregir la incontinencia urinaria o con diagnóstico de deficiencia intrínseca del esfínter a las que se les practicó el procedimiento de cabestrillo reajustable (Remeex Female Neomedic) entre el 2016 y el 2019. RESULTADOS: Se evaluaron 19 pacientes con media de edad de 62 años (DE ± 9). La mediana de seguimiento fue de 19.4 meses (RIQ 10-26.5). Todas las pacientes tenían urodinamia prequirúrgica que confirmó el diagnóstico de incontinencia urinaria de esfuerzo. Las 19 pacientes tuvieron diagnóstico de incontinencia urinaria moderada-severa-recurrente, 4 con hipoactividad del detrusor y 1 con deficiencia intrínseca del esfínter. De las 19 pacientes, a 10 se les intervino para corrección de prolapso de órganos pélvicos concomitante, que se distribuyeron en: 6 pacientes con colporrafia anterior o posterior, 3 colpocleisis y 1 sacrocolpopexia por laparotomía. CONCLUSIONES: El cabestrillo reajustable es una buena opción para mujeres con intervenciones previas antiincontinencia con recidiva en quienes se demostró la mejoría en el grado de incontinencia en relación con el inicial, beneficio que se reflejó en mejor calidad de vida.

Abstract OBJECTIVE: To describe the experience with the readjustable sling Remeex® in patients with recurrent stress urinary incontinence as a treatment alternative. MATERIALS AND METHODS: Retrospective, observational, case series study carried out in a single center in the city of Medellin, Colombia, in patients attended at the Urogynaecology Unit of the Bolivarian University Clinic. Inclusion criteria: women over 18 years of age, with a diagnosis of recurrent urinary incontinence after one or more failed surgeries to correct urinary incontinence or with a diagnosis of intrinsic sphincter deficiency who underwent the readjustable sling procedure (Remeex Female Neomedic) between 2016 and 2019. RESULTS: Nineteen patients were evaluated with mean age 62 years (SD ± 9). The median follow-up was 19.4 months (RIQ 10-26.5). All patients had preoperative urodynamics that confirmed the diagnosis of stress urinary incontinence. All 19 patients had a diagnosis of moderate-severe-recurrent urinary incontinence, 4 with detrusor hypoactivity and 1 with intrinsic sphincter deficiency. Of the 19 patients, 10 underwent surgery for correction of concomitant pelvic organ prolapse, which were distributed as follows: 6 patients with anterior or posterior colporrhaphy, 3 colpocleisis and 1 sacrocolpopexy by laparotomy. CONCLUSIONS: The readjustable sling is a good option for women with previous anti-incontinence interventions with recurrence in whom improvement in the degree of incontinence in relation to the initial one was demonstrated, a benefit that was reflected in better quality of life.

Intervención de cuidados enfermeros en adultos medios con diabetes mellitus tipo 2 según Kristen Swanson

Introducción: La diabetes mellitus se considera un problema de salud a nivel mundial. Esto se debe a sus crecientes y elevadas tasas de incidencia y prevalencia. Objetivo: Evaluar la intervención de cuidados enfermeros en adultos medios con diabetes mellitus tipo 2 según Kristen Swanson. Métodos: Se realizó un estudio de intervención y desarrollo en el Centro de Salud del municipio Cuito y provincia Bie, país Angola desde el año 2021 al 2022. Realizado a 98 adultos medios, fueron utilizadas variables como: sexo, escolaridad, años de control de la enfermedad, antecedentes de diabetes en la familia y estado de salud. Se utilizó entrevista estructurada, después de aplicada la intervención se compararon las proporciones poblacionales mediante la prueba de McNemar. Resultados: Recibieron un cuidado aceptable, el 80,61 % de los adultos. Tenía familiares con antecedentes de diabetes 37,75 %, escolaridad básica 57,14 %. Los años de control de la diabetes, 38,77 % de los encuestados manifestaron eran controlados desde hacía 3-5 años y el estado de salud de los adultos fue alto con un 79,59 %. Conclusiones: La intervención de cuidados enfermeros en adultos medios con diabetes mellitus tipo 2 según la teoría de Kristen Swanson fue efectiva al modificar el cuidado y el estado de salud de los que participaron en el estudio.

Introduction: Diabetes mellitus is considered a global health problem. This is due to its increasing and high incidence and prevalence rates. Objective: To evaluate the nursing care intervention in middle adults with type 2 diabetes mellitus according to Kristen Swanson. Methods: An intervention and development study was carried out in the Health Center of the Cuito municipality and Bie province, Angola country from 2021 to 2022. It was carried out on 98 middle adults, the used variables were: Sex, education, years of disease control, history of diabetes in the family, health status. A structured interview was used, after the intervention was applied, the population proportions were compared using the McNemar test. Results: 80.61% of adults received acceptable care. 37.75% had family members with a history of diabetes, 57.14% had basic education. The years of diabetes control, 38.77% of those surveyed stated that they had been controlled for 3 to 5 years and the health status of adults was high at 79.59%. Conclusion: The nursing care intervention in middle adults with type 2 diabetes mellitus according to Kristen Swanson's theory was effective in modifying the care and health status of those who participated in the study.

The association between social support and self-rated health in midlife: are men more affected than women? / Associação entre suporte social e autoavaliação de saúde na meia-idade: seriam os homens mais afetados que as mulheres? / La asociación entre el apoyo social y la autoevaluación de salud en la mediana edad: ¿se afectan los hombres más que las mujeres?

Abstract: Social support from family and friends is recognized as an important social determinant of health, given its protective effects on individuals' physical and mental well-being. While most studies have focused on older adults, investigating midlife health is equally crucial since middle-aged individuals are also susceptible to the harmful health outcomes of inadequate social support from friends and family. This study contributes to the debate by examining whether social support is associated with self-rated health among middle-aged Brazilian adults and how this relationship varies between men and women. Using data from the nationwide Brazilian National Health Survey conducted in 2019, logistic regression models were employed to assess differences in self-rated health, accounting for confounding factors. The sample comprised 31,926 middle-aged adults, of which 52.5% were women. The overall prevalence of poor self-rated health was 40.7%, with a significant difference between men and women. Results from this study suggest that having no friends or family members to rely on, both during good and challenging times, was associated with poorer self-rated health. However, the strength of this association differs by gender, with social support from friends playing a more critical role in women's self-rated health. On the other hand, family support was associated with male self-rated health, particularly for men with three or more family members they can rely on. Future studies should consider cultural and contextual factors to better understand other dimensions of social support and its association with midlife health.

Resumo: O suporte social de familiares e amigos é reconhecido como um importante determinante social da saúde com base em seus efeitos protetores sobre o bem-estar físico e mental dos indivíduos. Embora a maioria das pesquisas tenha se concentrado em adultos mais velhos, investigar a saúde na meia-idade é igualmente crucial, já que estes indivíduos também são suscetíveis aos resultados prejudiciais à saúde decorrentes do suporte social inadequado de amigos e familiares. Este estudo contribui para o debate ao examinar se o suporte social está associado à autoavaliação da saúde entre adultos brasileiros de meia-idade e como essa relação varia entre homens e mulheres. Usando dados da Pesquisa Nacional de Saúde realizada em 2019, modelos de regressão logística foram empregados para avaliar diferenças na autoavaliação da saúde, contabilizando fatores de confusão. A amostra foi composta por 31.926 adultos de meia-idade, dos quais 52,5% eram mulheres. A prevalência geral de autoavaliação de saúde ruim foi de 40,7%, com diferença significativa entre homens e mulheres. Os resultados deste estudo sugerem que não ter amigos ou familiares com quem contar em momentos bons ou desafiadores esteve associado à pior autopercepção de saúde. No entanto, a força dessa associação difere de acordo com o gênero, sendo que o suporte social de amigos desempenha um papel mais importante na autoavaliação da saúde das mulheres do que na dos homens. Por outro lado, o apoio familiar esteve associado à autoavaliação da saúde masculina, particularmente para homens com três ou mais membros da família com quem podem contar. Estudos futuros devem considerar fatores culturais e contextuais para compreender melhor outras dimensões do suporte social e sua associação com a saúde na meia-idade.

Resumen: El apoyo social de la familia y de amigos se reconoce como un importante determinante social de salud basado en sus efectos protectores sobre el bienestar físico y mental de los individuos. Aunque la mayoría de las investigaciones se ha centrado en adultos mayores, investigar la salud en la mediana edad también es esencial, una vez que estos individuos también son susceptibles a los resultados perjudiciales para la salud resultantes de un apoyo social inadecuado de amigos e de la familia. Este estudio contribuye al debate al investigar si el apoyo social está asociado con la autoevaluación de salud entre adultos brasileños de mediana edad y cómo esa relación varía entre hombre y mujeres. Usando datos de la Encuesta Nacional de Salud realizada en 2019, se utilizaron modelos de regresión logística para evaluar diferencias en la autoevaluación de salud, contabilizando factores de confusión. La muestra se compuso de 31.926 adultos de mediana edad, de los cuales el 52,5% eran mujeres. La prevalencia general de autoevaluación de mala salud fue del 40,7%, con diferencia significativa entre hombres y mujeres. Los resultados de este estudio sugieren que no tener amigos o familiares en los que confiar en buenos o malos momentos se asoció con la peor autopercepción de salud. Sin embargo, la fuerza de esa asociación es diferente según el género, ya que el apoyo social de amigos es más importante en la autoevaluación de salud de las mujeres que en la autoevaluación de los hombres. Por otro lado, el apoyo familiar se asoció con la autoevaluación de la salud masculina, particularmente para hombres que tenían tres o más personas de la familia en los que confiar. Estudios futuros deben tener en cuenta factores culturales y contextuales para mejor comprender otras dimensiones del apoyo social y su asociación con la salud en la mediana edad.

Matriz analítica de vulnerabilidade da população adulta para Covid-19: uma revisão integrativa / Analytic Matrix of vulnerability to Covid-19 among the adult population: an integrative review

Resumo Sintetizar os elementos de vulnerabilidade da população adulta para a Covid-19. Método: Revisão integrativa, realizada entre agosto e novembro de 2020, com critérios definidos de inclusão, exclusão e recuperação dos estudos, de extração e síntese dos dados, pela análise temática categorial e sistematização pela vulnerabilidade. Resultados mais relevantes: De 2.247 artigos recuperados, foram selecionados e avaliados 70 estudos originais com leitura integral. Emergiram da análise temática quatro marcadores de vulnerabilidade: Condições crônicas de saúde; Experiências de vida e cotidiano; Inserção social; e Serviços e ações de saúde. Principais conclusões: Os marcadores de vulnerabilidade identificados poderão subsidiar os profissionais de saúde na identificação dos pacientes com menos autonomia e recursos para o autocuidado e proteção contra a Covid-19, além da adoção de intervenções em saúde e intersetoriais que as protejam mais contra a infecção por Covid-19, diminuindo as taxas de transmissão do SARS-Cov-2 dentro das comunidades e outros espaços, com a redução significativa do impacto do vírus sobre a sociedade.

Abstract Objective: To synthesize the elements of vulnerability to Covid-19 among the adult population. Method: Integrative review carried out between August and November 2020, with defined criteria of inclusion, exclusion and retrieving of studies. Data were extracted and synthesized by means of the categorical thematic analysis, and systematized by the vulnerability concept. Most relevant results: From 2247 articles retrieved, 70 original studies were selected, fully read and assessed. Four vulnerability markers emerged: Chronic Health Conditions; Daily Life Experiences; Social Insertion; and Health Services and Actions. Main conclusions: The identified vulnerability markers may support health professionals in the identification of patients with less autonomy and resources for self-care and protection against Covid-19. They may also foster the adoption of health and intersectoral interventions to protect patients against Covid-19, as well as the reduction of SARS-Cov-2 transmission rates within communities and other settings, with significant decline in the impact of the virus on society.

Transtornos alimentares: vivências de mulheres acima de 30 anos / Eating disorders: experiences of women aged over 30 years / Trastornos alimentarios: experiencias de mujeres de más de 30 años

O objetivo deste estudo foi compreender como mulheres adultas (acima de 30 anos) diagnosticadas com transtornos alimentares (TAs) vivenciam o adoecer. Trata-se de um estudo qualitativo, descritivo e exploratório, desenvolvido com base no referencial teórico-metodológico da Análise Fenomenológica Interpretativa (AFI). Participaram seis mulheres, com idades entre 34 e 65 anos, atendidas em um serviço especializado. Os dados foram coletados por meio de entrevista aberta, de inspiração fenomenológica, na modalidade remota. As entrevistas foram audiogravadas, transcritas e analisadas seguindo os passos da AFI. Duas categorias temáticas foram identificadas: "Vivendo antes do adoecer" e "Encontrando-se doente." Constatou-se que os sintomas tiveram início anteriormente à vida adulta e que houve dificuldade na confirmação do diagnóstico. Na perspectiva das participantes, conviver com a sintomatologia ficou mais complicado em função de particularidades de manejo dos sintomas na vida adulta, e a idade é percebida como um fator que impacta e dificulta ainda mais a recuperação. As participantes relataram desesperança em relação ao futuro, apesar de a maioria reconhecer melhoras no quadro clínico ao longo do tempo e de valorizar a relação de confiança estabelecida com a equipe multiprofissional.(AU)

This study aimed to understand the experience of illness of adult women (over 30 years) diagnosed with eating disorders (ED). This is a qualitative, descriptive, and exploratory study, using Interpretative Phenomenological Analysis (IPA) as theoretical and methodological framework. A sample of six women aged 34-64 years, assisted in a specialized service, were recruited to complete a phenomenological in-depth open interview. The data were remotely collected. Interviews were audio-recorded, transcribed and analyzed following the IPA. Two thematic categories were identified: "Living before the illness" and "Finding about the illness." It was found that the symptoms started before adulthood and that there was difficulty establishing the diagnosis. Living with the symptoms became more complicated due to particularities of symptom management in adulthood and age is perceived as a factor that impacts recovery and makes it even more difficult. The participants reported hopelessness about the future, although most recognized improvements in the clinical condition over time and valued the trusting relationship they established with the multiprofessional team.(AU)

El objetivo de este estudio fue comprender las experiencias de las mujeres adultas (mayores de 30 años) diagnosticadas con trastornos alimentarios (TA) respecto a la enfermedad. Se trata de un estudio cualitativo, descriptivo y exploratorio, desarrollado a partir del marco teórico y metodológico del Análisis Fenomenológico Interpretativo (AFI). Participaron seis mujeres, con edades de entre 34 y 65 años, atendidas en un servicio especializado. Los datos se recogieron mediante entrevistas abiertas, de inspiración fenomenológica, en la modalidad a distancia. Las entrevistas fueron grabadas en audio, transcritas y analizadas siguiendo los pasos del AFI. Se identificaron dos categorías temáticas: "Vivir antes de enfermar" y "Encontrarse enfermo." Se constató que los síntomas comenzaron antes de la edad adulta y que hubo dificultades de establecer el diagnóstico. La convivencia con síntomas se complicó debido a las particularidades del manejo de los síntomas en la vida adulta y la edad se percibe como un factor que influye y dificulta aún más la recuperación. Los participantes manifestaron desesperanza sobre el futuro, aunque reconocieron mejoras en el cuadro clínico con el paso del tiempo y valoraron la relación de confianza establecida con el equipo multiprofesional.(AU)

Tai chi influence on cardiopulmonary function in the elderly / Influência do tai chi na função cardiopulmonar de idosos / Influencia del tai chi en la función cardiopulmonar de las personas mayores

ABSTRACT Introduction: Cardiopulmonary function testing is a fundamental component of the physical examination and an elementary indicator for measuring physical fitness. With advancing age, the cardiopulmonary system will undergo a series of aging changes in morphology and function. Objective: Explore the effect of Tai Chi exercise on cardiopulmonary function in middle-aged and elderly people. Methods: A total of 73 50-75 years old from 5 areas in our city were recruited. A total of 63 healthy subjects were selected, 37 in the exercise group and 26 in the non-exercise group. The heart rate, lung capacity, and 6-min walking distance of each subject were measured in a calm state during the recovery time after walking 10 min after recovery. Results: In a calm state, Tai Chi practitioners had better lung capacity and a lower heart rate than non-practitioners (p0.05). In the immediate recovery time after walking, Tai Chi exercise elevated lung capacity more than non-exercisers (p0.01). Conclusion: Tai Chi exercise can improve the adaptability of cardiopulmonary function in middle-aged and elderly people after exercise. Level of Evidence: Therapeutic Studies - Outcome Investigation.

RESUMO Introdução: O teste de função cardiopulmonar é um elemento fundamental no exame físico, e também um indicador elementar corrente para medir a aptidão física. Com o avanço da idade, o sistema cardiopulmonar passará por uma série de mudanças de envelhecimento na morfologia e função. Objetivo: Explorar o efeito do exercício de Tai Chi sobre a função cardiopulmonar de pessoas de meia-idade e idosas. Métodos: Um total de 73, 50-75 anos de idade de 5 áreas em nossa cidade foram recrutados. Foram selecionados 63 sujeitos saudáveis, 37 no grupo de exercícios e 26 no grupo de não-exercício. O ritmo cardíaco, a capacidade pulmonar e a distância de caminhada de 6 minutos de cada sujeito foram medidas em um estado calmo, durante o tempo de recuperação após a caminhada, e 10 minutos após o período de recuperação. Resultados: Em um estado calmo, os praticantes de Tai Chi apresentam uma melhor capacidade pulmonar e uma frequência cardíaca menor do que os não praticantes (p0,05). No tempo de recuperação imediata após a caminhada, o exercício de Tai Chi elevou a capacidade pulmonar mais do que os não-exercitantes (p0,01). Conclusão: O exercício de Tai Chi pode melhorar a adaptabilidade da função cardiopulmonar em pessoas de meia-idade e idosos após o exercício. Nível de evidência: Estudos Terapêuticos - Investigação dos Resultados.

RESUMEN Introducción: La prueba de función cardiopulmonar es un elemento fundamental en el examen físico, y también un indicador elemental actual para medir la aptitud física. Con el avance de la edad, el sistema cardiopulmonar sufrirá una serie de cambios de envejecimiento en su morfología y función. Objetivo: Explorar el efecto del ejercicio de Tai Chi sobre la función cardiopulmonar en personas de mediana y avanzada edad. Métodos: Se reclutó a un total de 73 personas de 50 a 75 años de edad de 5 zonas de nuestra ciudad. Se seleccionó un total de 63 sujetos sanos, 37 en el grupo de ejercicio y 26 en el grupo de no ejercicio. Se midieron la frecuencia cardíaca, la capacidad pulmonar y la distancia recorrida en 6 minutos de cada sujeto en estado de calma, durante el tiempo de recuperación tras la marcha y 10 minutos después del periodo de recuperación. Resultados: En un estado de calma, los practicantes de Tai Chi tenían una mejor capacidad pulmonar y una menor frecuencia cardíaca que los no practicantes (p0,05). En el tiempo de recuperación inmediata tras la marcha, el ejercicio de Tai Chi aumentó la capacidad pulmonar más que los no practicantes (p0,01). Conclusión: El ejercicio de Tai Chi puede mejorar la adaptabilidad de la función cardiopulmonar en personas de mediana y avanzada edad después del ejercicio. Nivel de evidencia: Estudios terapéuticos - Investigación de resultados.

Avaliação comportamental do processamento auditivo na idade adulta: população de interesse e testes - uma revisão sistemática / Behavioral assessment of auditory processing in adulthood: population of interest and tests - a systematic review

RESUMO Objetivo Identificar os testes comportamentais utilizados para a avaliação do processamento auditivo ao longo da vida adulta, com enfoque nas características da população alvo enquanto grupo de interesse. Estratégia de pesquisa As bases de dados consultadas foram o PubMed, CINAHL, Web of Science e Scielo, a partir dos descritores: "auditory perception" or "auditory perception disorders" or "auditory processing" or "central auditory processing" or "auditory processing disorders" or "central auditory processing disorders" com adults OR aging. Critérios de seleção Incluiu-se estudos com humanos, que abordaram a população adulta de 18 a 64 anos, que realizaram pelo menos um teste comportamental para avaliação do processamento auditivo, na ausência de perda auditiva. Análise dos dados Realizou-se a extração de dados de forma independente, a partir de um protocolo desenvolvido pelos autores incluindo diferentes tópicos, principalmente os testes auditivos comportamentais realizados e os resultados encontrados. Resultados Dos 867 registros identificados, 24 foram selecionados como contendo as informações necessárias para responder às perguntas de pesquisa. Conclusão Quase a totalidade dos estudos foi conduzida com objetivo de verificar o desempenho em um ou dois testes de processamento auditivo; a população alvo foi heterogênea, as mais frequentes foram diabetes, gagueira, transtorno do processamento auditivo e exposição ao ruído. Há poucas informações sobre os padrões de referência para os testes na respectiva faixa etária.

ABSTRACT Purpose To identify the behavioral tests used to assess auditory processing throughout adulthood, focusing on the characteristics of the target population as an interest group. Research strategies PubMed, CINAHL, Web of Science, and Scielo, databases were searched with descriptors: "auditory perception" or "auditory perception disorders" or "auditory processing" or "central auditory processing" or "auditory processing disorders" or "central auditory processing disorders" with adults OR aging. Selection criteria Studies with humans included, the adult population from 18 to 64 years old, who performed at least one behavioral test to assess auditory processing in the absence of hearing loss. Data analysis Data extraction was performed independently, using a protocol developed by the authors that included different topics, mainly the behavioral auditory tests performed and the results found. Results Of the 867 records identified, 24 contained the information needed to answer the survey questions. Conclusion Almost all studies were conducted verify performance in one or two auditory processing tests. The target target population was heterogeneous, with the most frequent persons with diabetes, stuttering, auditory processing disorder, and noise exposure. There is little information regarding benchmarks for testing in the respective age groups.

Executive function performance in middle-aged adults / Desempenho da função executiva em adultos de meia-idade

ABSTRACT. Executive functions have been widely studied in the extreme of ages, but studies in middle-aged adults remain largely neglected. Education and gender are known to influence cognitive performance; however, their effect on executive function in middle-aged adults remains unclear. Objective: The study aimed to observe the effect of hierarchy of educational qualifications (graduate, postgraduate, and PhD) and gender on various executive function tests across middle-aged adults with or without comorbidity. Methods: A total of 66 middle-aged individuals volunteered for the study (mean age=48.45±5.45 years; 20 graduates, 28 postgraduates, and 18 PhD; 36 males and 30 females; 38 healthy adults and 28 adults with comorbidities). Each subject performed a test assessing short-term memory, spatial working memory, and multitasking abilities on the Cambridge Neuropsychological Test Automated Battery with rest periods in no specific order of tests. Key parameters of cognitive tests were analyzed for differences in educational qualifications (ANOVA), gender (t-test), and the effect of comorbidity as a covariate (ANCOVA). Results: PhDs performed significantly better (p<0.05) in multitasking than graduates and had superior visuospatial working memory (fewer errors). Differences in simultaneous matching abilities, lower incongruence cost and multitasking cost were statistically significant in healthy females than in males. Conclusion: On considering adults with comorbidity, those with higher educational attainment retained the ability to multitask compared to their healthy counterparts, which was not seen in the group with lower educational attainment. Thus, higher educational attainment attenuated the influence of comorbidities and deterioration of executive functions in general in middle-aged adults.

RESUMO. As funções executivas têm sido amplamente estudadas no extremo das idades, mas os estudos na meia-idade permanecem amplamente negligenciados. Educação e gênero são conhecidos por influenciar o desempenho cognitivo, no entanto, seu efeito na função executiva em adultos de meia-idade ainda não está claro. Objetivo: O estudo teve como objetivo observar o efeito da hierarquia de qualificações educacionais (graduação, pós-graduação e doutorado) e gênero em vários testes de função executiva em adultos de meia-idade com ou sem comorbidade. Métodos: Sessenta e seis indivíduos de meia idade se voluntariaram para participar do estudo (idade média=48,45±5,45 anos, 20 graduados, 28 pós-graduados e 18 doutores; 36 homens e 30 mulheres; 38 saudáveis e 28 adultos com comorbidades). Cada sujeito realizou um teste avaliando memória de curto prazo, memória de trabalho espacial e habilidades multitarefa na Bateria Automatizada de Testes Neuropsicológicos de Cambridge (Cambridge Neuropsychological Test Automated Battery — CANTAB) com períodos de descanso em nenhuma ordem específica de testes. Os principais parâmetros dos testes cognitivos foram analisados quanto às diferenças nas qualificações educacionais (ANOVA), sexo (teste t) e efeito da comorbidade como uma covariável (ANCOVA). Resultados: Os doutores tiveram desempenho significativamente melhor (p<0,05) em multitarefa do que os graduados e tiveram memória de trabalho visual-espacial superior (menos erros). As diferenças nas habilidades de correspondência simultânea, menor custo de incongruência e custo de multitarefa foram estatisticamente significativas em mulheres saudáveis do que em homens. Conclusão: Ao considerar os adultos com comorbidade, aqueles com maior escolaridade mantiveram a capacidade de multitarefa como seus pares saudáveis, o que não foi observado no grupo com menor escolaridade. Assim, maior escolaridade atenuou a influência de comorbidades e deterioração das funções executivas em geral, em adultos de meia-idade.

Development of General Practice in Communities From the Perspective of Supply and Demand / 中国医学科学院学报

Objective To put forward suggestions for improving the scheme of general practice for functional communities from the perspective of supply and demand,guide the efficient use of the resources of general practice by the communities,and incorporate the general practice of communities into hierarchical diagnosis and treatment management. Methods In July 2021,stratified random sampling was employed to conduct the questionnaire surveys of the young and middle-aged (demand side) and the general practitioners (supply side),respectively.SPSS 20.0 was used for data analysis. Results The two sides had the same cognition about the main reasons for not signing a contract with a family doctor,which were the lack of knowledge about general practitioners and the lack of face-to-face communication opportunities.They had the same response about the form of services,with high acceptance of medical services via WeChat,outpatient consultation,and the internet.There were differences in service content between the two sides.The top three demands of the young and middle-aged were appointment registration and referral in superior hospitals,medication guidance,and massage,acupuncture,and moxibustion.The top service self-rated by general practitioners was personalized guidance and report interpretation of physical examination,and the bottom was massage,acupuncture,and moxibustion. Conclusions The general practice varies between the demand and supply sides.General practitioners should be encouraged to enter and learn functional communities and provide personalized services,thus improving the general medical service in functional communities.

Effect of Age and Sex on Stroke Mortality of Young and Middle-aged Adults in China, 2002-2019, and Predictions to 2030 / 生物医学与环境科学（英文）

OBJECTIVE@#This study aimed to examine the trends in stroke mortality among young and middle-aged adults in China.@*METHODS@#Data were obtained from the China national vital registration system. Significant changes in mortality were assessed by Joinpoint regression. Age-period-cohort analysis was used to explain the reasons for the changes. Future mortality and counts were predicted by the Bayesian age-period-cohort model.@*RESULTS@#Between 2002 and 2019, a total of 6,253,951 stroke mortality in young and middle-aged adults were recorded. The age-adjusted mortality rates (AAMRs) of women showed a downward trend. The annual percent changes (APC) were -3.5% (-5.2%, -1.7%) for urban women and -2.8% (-3.7%, -1.9%) for rural women. By contrast, the AAMRs per 100,000 for rural men aged 25-44 years continued to rise from 9.40 to 15.46. The AAMRS for urban men aged 25-44 years and urban and rural men aged 45-64 years did not change significantly. Between 2020 and 2030, the projected stroke deaths are 1,423,584 in men and 401,712 in women.@*CONCLUSION@#Significant sex and age disparities in the trends of stroke mortality among young and middle-aged adults were identified in China. Targeted health policy measures are needed to address the burden of stroke in the young generation, especially for rural men, with a focus on the prevention and management of high risk factors.