Unusual treatment of pleomorphic adenoma of soft palate in adult / Tratamiento inusual del adenoma pleomórfico del paladar blando en adulto

Pleomorphic adenoma is the most common benign neoplasia of the salivary glands and affects mostly the parotid gland, less frequently the minor salivary glands. Minor salivary gland tumors have a higher risk of malignancy compared to tumors of the major salivary glands, so appropriate diagnostic evaluation should be prompt. In this case report, we present a case of an extensive pleomorphic adenoma of soft palate in an adult patient. After preoperative investigation using Fine Needle Aspiration (FNA) and imaging tests, the patient was successfully treated by surgical resection under general anesthesia. There was no recurrence seen after a follow-up period of 1 year.

El adenoma pleomórfico es la neoplasia benigna más común de las glándulas salivales y afecta principalmente la glándula parótida, con menos frecuencia en las glándulas salivales menores. Los tumores de las glándulas salivales menores tienen un mayor riesgo de malignidad en comparación con los tumores de las glándulas salivales mayores, por lo que la evaluación diagnóstica apropiada debe ser rápida. En este reporte de caso, presentamos un caso de un extenso adenoma pleomórfico de paladar blando en un paciente adulto. Después de la investigación preoperatoria utilizando aspiración con aguja fina y pruebas de imagen, el paciente fue tratado con éxito con la resección quirúrgica bajo anestesia general. No se observó recurrencia después de un período de seguimiento de 1 año.

Pleomorphic Adenoma of a Minor Salivary Gland of the Hard Palate Report of a Case

The pleomorphic adenoma is the most common benign tumor of the minor salivary glands and is comprised of epithelial and mesenchymal tissues. The majority of the salivary gland tumors occur in the second decadeof life with a slight predilection for females. Clinically it presents as a firm or rubbery submucosal mass without ulceration or surrounding inflammation. Diagnosis is established on the clinical examination and histopathology, supplemented with plane radiographs, computerized tomography, and magnetic resonance imaging when necessary. Here, we report a case of pleomorphic adenoma of the hard palate in a 21-year-old female patient with a painless swelling in the left palatal region of nine months duration.

Pleomorphic Adenoma with Predominant Myoepithelial Cells of the Hard Palate: Reconstruction with Pedicled Buccal Pad of Fat – A Case Report.

Pleomorphic adenoma is a mixed tumor of salivary gland origin presenting frequently in major salivary glands and sporadically in minor salivary glands. It is a benign tumor with both epithelial and mesenchymal tissues. Salivary glands in general may present with a diverse range of lesions posing a challenge to even the most experienced clinician. Resection with surrounding dispensable normal tissues is the key to successful management of such tumors. This case report illustrates an enormous pleomorphic adenoma of minor salivary gland in the hard palate of 10 years duration.

Adenoid cystic carcinoma arising from minor salivary glands of palate involving maxillary sinus.

Adenoid cystic carcinoma (ACC) was first described by Billroth in 1856 and was called ‘cylindroma’ due to its characteristic histological appearance. ACC is the most common malignant neoplasm of the lacrimal gland, and the second most common type of carcinoma arising in the salivary glands, following mucoepidermoid carcinoma. Palate is the most commonly affected site followed by parotid gland, submandibular gland, antrum & tongue. Characteristic features include aggressive, slow growth, with insidious destruction of surrounding tissues, perineural invasion, prolonged clinical course and the tendency for delayed onset of the distant metastases which worsens the prognosis. Long term survival can be achieved particularly with combined surgery and radiotherapy. The most common pattern is the cribriform architecture. Histopathology is the gold standard for the diagnosis of ACC. CT & MRI are considered to be of almost similar significance in detection of perineural spread with preference to MRI because of its high soft tissue contrast. Here we have mentioned a case of Adenoid Cystic carcinoma arising from minor salivary glands of palate.

Myoepithelial carcinoma of palate: Case report.

Myoepithelial carcinoma is an uncommon malignant salivary gland neoplasm with a predilection for parotid gland. However, its occurrence in minor salivary glands is considerably less with only 28 cases being reported in the literature. We report a case of myoepithelial carcinoma of palate in a 50-year-old woman. Computed tomography and magnetic resonance imaging revealed an extensive lesion in the palate. Microscopically, the tumor exhibited a wide spectrum of cytomorphologic features that overlap with other salivary gland tumors. Immunohistochemistry served as an adjunct in the diagnosis of the lesion. Clinical, radiographic, and histopathologic correlation along with immunohistochemical profi le enabled to arrive at a diagnosis of myoepithelial carcinoma.

6 Cases of Salivary Gland Tumors Arising at Buccal and Masseteric Area

This is a case report of salivary gland tumors developed at buccal fat pad and masseteric area which are considered rare and characterized by asymptomatic mid-cheek mass. Three cases were diagnosed as accessory parotid gland tumor and the other 3 cases as minor salivary gland tumor with tissue pathology. Accessory parotid gland lies 6 mm anterior to the main parotid gland and accessory parotid gland tumors represent 1% of all parotid tumor. It can be managed solely by resection of the accessory parotid gland without superficial or total parotidectomy. Minor salivary gland tumors represent 10-20% of all salivary gland tumor and are usually found on the palate, paranasal sinuses and cheek. Buccal minor salivary gland tumors are usually found incidentally as submucosal mass at buccal mucosa and managed by wide excision including 1-2 cm free margin through intra-oral approach. This paper reviews our experience with these unusual tumors in terms of clinical manifestation, radiologic findings and the acceptable surgical management.

A Clinical Analysis in Minor Salivary Gland Tumor / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Minor salivary gland tumors vary in their primary sites, histopathology and biological behavior. Therefore, various factors are considered in selecting the treatment modality and predicting the prognosis. Generally, it is reported that the prognosis of malignant tumors of minor salivary glands are worse than that of such lesions of major salivary glands. We performed this study to find out the clinical features and determine the prognostic factors of minor salivary gland tumors. MATERIALS AND METHODS: We analyzed retrospectively, 83 cases of minor salivary gland tumor and the 10 year survival rates using the Kaplan-Meier method. RESULTS: We found 16 benign tumors and 67 malignant tumors. Among the patients, 43 were males and 40 were females. The most common age group was the sixties, with the mean age of 50. The most common site of benign tumor was the palate, whereas malignant tumors were most commonly found in the maxillary sinus, palate, and floor of mouth, etc. Histopathologically, 14 patients with benign tumor had pleomorphic adenoma, and 39 patients with malignant tumor had adenoid cystic carcinoma. According to the criteria set by the AJCC on staging, the most common stage found for the subjects were the stage IV. Overall, the 5 year and 10 year survival rates were 56.1% and 46.9%, respectively. Histopathologic type had no effect on 10 year survival rates. The clinical stage had a significant impact on survival. CONCLUSION: In minor salivary gland tumor, the most significant prognostic factor was its clinical stage. Considering the frequent local recurrence and distant metastasis, long term follow ups will be needed.