Post-Operative Morphometric Analysis of Carpal Tunnel Syndrome using High Resolution Ultrasonography

We evaluated the morphologic changes that follow division of transverse carpal ligament in patients with carpal tunnel syndrome using high resolution sonography. Twenty hands of 10 patients underwent high- resolution ultrasonographic studies before the operation and 8 months after the operation. They were all diagnosed as bilateral idiopathic CTS. We evaluated the configuration of the median nerve and carpal tunnel at different three levels of the wrist; the distal radiocarpal joint level, the pisiform level, and the hook of hamate level. The median nerve remarkably gained its thickness at distal two levels after the operation. The morphology of carpal tunnel has also changed at distal levels. Increase in the anteroposterior diameter at distal two levels was obvious, but the cross sectional area of the carpal tunnel was increased significantly only at the hook of hamate level. The transverse diameters of the carpal tunnel were not significantly changed. As above, we found that the median nerve gained its volume significantly at distal part of carpal tunnel postoperatively, and the volumetric increase of carpal tunnel would have resulted from an anterior displacement of newly formed transverse carpal ligament and not from a widening of the bony carpal arch.

Primary Study on the Relationship between the Cystoid Type and the Sclerous Type Polycystic Ovarian Syndrome / 中国医师杂志

Objective To explore the relationships between the cystoid type and the sclerous type polycystic ovarian syndrome(PCOS). Methods We compared the similarities and differences between the two types of PCOS by blood sex hormone measuring,laparoscopy,pathomorphology and so on in 19 patients with cystoid type PCOS,26 with sclerous type PCOS and 10 controlled age-matched non-PCOS women.Results There was no remarkable difference in the sex hormone level between the two groups of PCOS.Compared with the patients with cystoid type PCOS,the patients with sclerous type PCOS had longer course of disease,thicker ovarian tunica albuginea,more collagen,and hyperplasia medulla and stroma.Conclusion The cystoid type PCOS could develop into the sclerous type PCOS when the disease progressed.

Morphologic Changes in Nasal Mucosa of the Rat after Ozone Exposure / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Ozone is the principal oxidant pollutant in photochemical smog. Although ozone-induced pulmonary changes have been morphologically characterized, effects of ozone on the upper respiratory tract have not been thoroughly investigated. The purpose of this study was to investigate the morphological change of nasal mucosa after acute exposure to ozone. MATERIAL AND METHODS: Rats are exposed to 0.3, 0.6, 0.9, and 1.2 ppm of 0, for 6 hours a day for 7 days. Rats were sacrificed 18h after the end of their last exposure. Nasal mucosa was processed for Hematoxylin/Eosin (H/E) stain and Alcian blue (pH 2.5)/Periodic Acid Schiff (AB/PAS) stain. RESULTS: Morphological changes such as infiltration of neutrophils, loss of cilia, epithelial hyperplasia, squamous metaplasia and secretory cell metaplasia were observed and these changes were more pronounced in the group exposed to high concentration of ozone, compared with the group exposed to low concentration. CONCLUSION: The results of this study may suggest that ozone exposure induces infiammatory, proliferative, and metaplastic responses in the nasal mucosa.

Changes in LV Mass, LV Morphology and Diastolic Function of LV in Response to Antihypertensive Treatment

BACKGROUND: Left ventricular hypertrophy is major cardiovascular risk factor for sudden death, acute myocardial infarction and congestive heart failure. Antihypertensive treatment able to normalize blood pressure and regression of left ventricular mass would also favorabley affect coronary flow reserve and cardiovascular mortality. OBJECT: This study was designed to explore changes of left venrtricular mass, echocardiographic datas such as interventricular septal thickness in diastole, posterior wall thickness in diastole, left ventricular end diastolic dimension, relative wall thickness, mainmorphologic change of LV, and diastolic function after antihypertensive treatment. METHODS: From May 1988 to Agust 1997, in 41 patients(14 men, 27 women) with estaiblished essential hypertension aged 35 to 78(mean 56+/-13) year were studied. We obtained the basal echocardiography and follow up echocardiography after treatment. RESULT: The results were as followings: 1) Baseline blood pressure was 157/92mmHg and fell to 137/81mmHg(p<0.001), and LV mass were reduced from 133.9g/mg2 to 132.9g/m2 without statistical significance. 2) Most of the patients(48.8%) were remained increased LV mass and only 12% of the patients were revert to normal LV mass. 3) Most of the patients remained same LV morphology after antihypertensive treatment. 4) Normalization of LV diastolic dysfunction was not observed after antihypertensive treatment. CONCLUSION: Most of the patients were remained increased LV mass, same morphology, and relaxation abnormality of LV after antihypertensive treatments. For analysis of our result, follow up studies are needed about regression of LV mass, remodeling of LV, diastolic function after antihypertensive treatment.