Mucinosis folicular primaria: presentación de un caso clínico tratado con tacrolimus unguënto al 0.1% / Primary follicular mucinosis: a case report treated with tacrolimus ointment 0.1 %

La mucinosis folicular se caracteriza por depósito anómalo de mucina, en los folículos pilosos y glándulas sebáceas. Puede corresponder a un trastorno idiopático benigno y auto-limitado, especialmente en niños o representar un cuadro secundario a un trastorno mielo-proliferativo, generalmente un linfoma cutáneo-T. Presentamos el caso de una niña de diez años de edad, con varias placas eritemato-blanquecinas circulares, ocasionalmente pruriginosas, en cara, cuello y tronco, además de alopecia difusa de cinco meses de evolución. No hay ataque al estado general. El estudio histopatológico reportó un cuadro compatible con mucinosis folicular.

Follicular mucinosis is characterized by mucin deposits within the hair follicles and sebaceous glands. It can occur as a primary idiopathic benign disorder; it can; or it can arise as a secondary symptom of a malignant disorder, most commonly mycosis fungoide. Youth and localization in a single area used to be regarded as indicative of the benign nature of follicular mucinosis. We report the case of a ten years old girl who presented with a five months history of a multiple, slightly pruritic, erythematous patches on her face, neck and chest. Different local treatments were ineffective. Overall, she was healthy. Histopathological examination of the lesion showed the typical histological picture of follicular mucinosis.

Mucinosis folicular primaria: simulando una tiña corporal / Primary follicular mucinosis: simulating a tinea corporis

La mucinosis folicular se caracteriza por depósito anómalo de mucina en los folículos pilosos y glándulas sebáceas. Puede corresponder a un trastorno idiopático benigno y autolimitado especialmente en niños, o representar un cuadro secundario a un trastorno mieloproliferativo, generalmente un linfoma cutáneo T. Presentamos el caso de una niña de 10 años de edad con varias placas eritematoblanquecinas circulares ocasionalmente pruriginosas en cara, cuello y tronco, además de alopecia difusa de 5 meses de evolución. No hay ataque al estado general. El estudio histopatológico reportó un cuadro compatible con mucinosis folicular.

Follicular mucinosis is characterized by mucin deposits within the hair follicles and sebaceous glands. It can occur as a primary idiopathic benign disorder; it can; or it can arise as a secondary symptom of a malignant disorder, most commonly mycosis fungoides. Youth and localization in a single area used to be regarded as indicative of the benign nature of follicular mucinosis. We report the case of a 10 -year old girl who presented with a 5- months history of a multiple, slightly pruritic, erythematous patches on her face, neck and chest. Different local treatments were ineffective. Overall, she was healthy. Histopathological examination of the lesion showed the typical histological picture of follicular mucinosis.

Mucinosis folicular: a propósito de dos casos / Follicular mucinosis: with regard to two cases

Las lesiones de Mucinosis folicular suelen localizarse en cabeza y más raramente extenderse a cuello, tronco y extremidades. Los hallazgos histológicos se caracterizan por la degeneración reticular del folículo pilosebáceo y el depósito de glicosaminoglicanos (mucina). Se presenta un caso de Mucinosis folicular generalizada, en una paciente de sexo femenino de 35 años de edad. Al examen dermatológico se visualizaban múltiples pápulas eritematosas, con predominio en tórax región posterior y cuero cabelludo, acompañadas de placas localizadas en pliegues y alopecia difusa. El segundo caso es de una paciente de sexo femenino de 26 años de edad. A la inspección presentaba placa eritematosa y nódulos dolorosos. Se destaca la necesidad de seguimiento clínico e histológico, ante la posibilidad de transformación a linfoma cutáneo.

The injuries of Follicular mucinosis usually are located in head or more rarely to become general to neck, trunk and extremities. The histological findings are characterized by the reticular degeneration of the pilosebaceous follicle and the deposit of glicosaminoglicans (mucin). A case of generalized Follicular mucinosis in a patient of feminine sex of 35 years of age appears. The dermatological examination revealed manifold papules with predominance in later thorax erythematous region and hairy leather, accompanied by plates that were located in you fold and diffuse alopecia. The second case is a patient of feminine sex of 26 years of age. The dermatological examination erythematous plate with painful nodules to the palpation was observed. The necessity of clinical and histological pursuit stands out before the cutaneous possibility of transformation to lymphoma.