A Case of Bilateral Internuclear Ophthalmoplegia

Internuclear ophthalmoplegia(INO) is a disorder of medial longitudinal fasciculus(MLF) that interconnects the ocular motor nuclei in the pons and midbrain. An intact MLF is essential for the production of all conjugate eye movements and an injury to the MLF results in ipsilateral adduction limitation and characteristic dissociated nystagmus of contralateral abducting eye. We experienced one case of bilateral internuclear ophthalmoplegia in a 70 years old ma, who had multiple lacunar infarctions in preaquductal gray matter, brain stem and basal ganglia.