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Abstract Objective: Bilateral Vocal Fold Paralysis (BVFP) is a rare but significant resource of respiratory distress in neonates and infants. The objective of this study was to evaluate the efficacy and functional outcomes of Endoscopic Percutaneous Suture Lateralization (EPSL) for the treatment of BVFP in neonates and infants. Methods: A case series study of nine patients undergoing EPSL for BVFP between January 2019 and June 2021 was conducted. All patients were candidates for tracheostomy prior to EPSL. Demographic features including gender, age at diagnosis and surgery, main symptoms, airway comorbidities, airway support, and etiology were collected preoperatively. Patients were evaluated for breathing, swallowing and phonation postoperatively. Surgical success was defined as the ability to avoid tracheostomy. Functional Endoscopic Evaluation of Swallowing (FEES) was conducted to identify aspiration. Voice evaluation was based on clinical observation. Results: Nine patients underwent ten EPSL procedures (one in the left vocal fold, and nine in the right vocal fold). Eight patients (8/9) were able to successfully avoid tracheostomy and feed orally without aspiration after the procedure. One patient experienced clinical improvement in respiratory support requirements and underwent laparoscopic nissen and gastrostomy tube placement. At the last follow-up, two patients regained normal voice, two patients had mild dysphonia, and five patients had moderate dysphonia. Five patients showed partial return of the contralateral vocal fold function. Conclusion: EPSL is an effective and safe treatment for neonatal and infantal BVFP, which enables patients free from tracheostomy without significant impact on swallowing function or phonation. Level of evidence: Level 4.
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OBJECTIVE To discuss the infection conditions of Mycoplasma pneumoniae(MP),Chlamydia pneumoniae(CP),Ureaplasma urealyticum(Uu),and Chlamydia trachomatis(CT) in the respiratory tracts of neonatal infants,and that of MP and CP among the infected children.METHODS Detecting MP,CP,Uu and CT in sputa of neonatal infants and MP and CP in throat swabs of children by the fluorescence quantitative polymerase chain reaction(FQ-PCR).RESULTS The positive rate of MP was 54.2%,4.9% and 10.0%(P0.05) in premature infants and term neonatal infants.CONCLUSIONS Infection rate of MP in premature infants is obviously higher than in term neonatal infants.The infection of CP is negative in all specimens.Infection rate of Uu in premature infants is higher than in term neonatal infants.Infection rate of CT has no statistical difference between premature infants and term neonatal infants.
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Objective Compare the analgesia effects of using different intervention method among neonatal infants, and then find out the most effective method. Methods Divided 120 neonatal infants into the control group, the NNS group and the position group, there were 40 cases in every group. Using the N-PASS scale evaluated the pain degree at the points of 1 and 5 minutes respectively after stimulation among the 3 groups. Results There was significant difference between the 3 groups on the pain degree,P