A Single Centre Experience of Spontaneous Bacterial Peritonitis in Ascites with Cirrhosis : A Record Based Observational Study

Spontaneous Bacterial Peritonitis (SBP) is one of the complicated infections in patients with cirrhosis and ascites which can be fatal if not diagnosed and treated. This is a record based observational study using the data of all patients admitted with established cirrhosis of liver with ascites. Aim of the study was to find out the incidence of SBP in cirrhosis patients and also to study the clinical profile of SBP. Thirty nine patients’ data were included in the study. Three patients had classic SBP, one patient had Culture Negative Neutrocytic Ascites (CNNA) and two had bacterascites. Patients were treated with injection cefotaxime (2 gm) 8hourly for 5 days and clinical and laboratory parameters were evaluated.

Cirrosis Hepática: características de la peritonitis bacteriana espontánea / Characteristics of spontaneous bacterial peritonitis

Objetivo: Establecer las características de peritonitis bacteriana espontánea en pacientes cirróticos con ascitis. Método: Se recopiló información de historias clínicas de pacientes cirróticos con ascitis ingresados en el servicio de gastroenterología. Resultados: el motivo de consulta más frecuente fue por aumento de la circunferencia abdominal (69,2%); somnolencia (29,9%), hematemesis (23,1%). El Child-Pugh fue 78,8% tipo B y 22,2% tipo C. Se evidenció asociación estadísticas entre la coinfección y peritonitis bacteriana espontánea (p = 0,013). Conclusión: La PBE es una complicación frecuente y grave de los pacientes con cirrosis hepática avanzada y ascitis. El diagnóstico y tratamiento precoz han conseguido mejorar el pronóstico en los últimos años.

Objective: To Establish the characteristics of spontaneous bacterial peritonitis in cirrhotic patients with ascites. Method: information from medical records of cirrhotic patients with ascites admitted to the gastroenterology was collected. Results: The most frequent reason for consultation was due to increased abdominal circumference (69.2 %); somnolence (29.9 %), hematemesis (23.1 %). The Child - Pugh was 78.8 % and 22.2 % type B type C statistical association between co-infection and spontaneous bacterial peritonitis (p = 0.013) was demonstrated. Conclusion: The PBE is a frequent and serious complication of patients with advanced liver cirrhosis and ascites. Early diagnosis and treatment have improved prognosis in recent years.