Application progress of nucleic acid aptamers in targeted drug delivery system / 药学实践杂志

Aptamers are single stranded oligonucleotides that have high affinity and specificity towards a wide range of target molecules .Owing to the indispensable advantages ,aptamers have wildly prospects and have become a research hotspot in targeted drug delivery system (TDDS) .In this article ,application advantage and progress of aptamers in TDDS were briefly reviewed ,the problems and prospects were also discussed .

Nucleic acid aptamers and their applications in the diagnosis and treatment of tumor / 国外医学(肿瘤学分册)

Nucleic acid aptamers are ligands with high specificity and affinity for their targets, which are screened from large oligonucleotide pools by the SELEX technology. Their characteristics are superior to antibodies in many aspects, which make them important in the research of recognition of molecules. They can be used to determine the levels and inhibit the bioactivity of their targets. There're broad application prospects for aptamers in the diagnosis and treatment of tumor.

Perspective on Research and Application of Nucleic Acid Aptamers in Environment Toxicology / 环境与健康杂志

Nucleic acid aptamers are ligands with high specificity and affinity for their targets,which are screened from large oligonucleotide pools by the SELEX (systematic evolution of ligands by exponential enrichment,SELEX) technology. For their specific character,they have shown the great applicative prospects in the environment toxicology and related research fields. The recent related researches were reviewed in the present paper.