Expert knowledge-based strategies for ventilator parameter setting and stepless adaptive adjustment / 生物医学工程学杂志

The setting and adjustment of ventilator parameters need to rely on a large amount of clinical data and rich experience. This paper explored the problem of difficult decision-making of ventilator parameters due to the time-varying and sudden changes of clinical patient's state, and proposed an expert knowledge-based strategies for ventilator parameter setting and stepless adaptive adjustment based on fuzzy control rule and neural network. Based on the method and the real-time physiological state of clinical patients, we generated a mechanical ventilation decision-making solution set with continuity and smoothness, and automatically provided explicit parameter adjustment suggestions to medical personnel. This method can solve the problems of low control precision and poor dynamic quality of the ventilator's stepwise adjustment, handle multi-input control decision problems more rationally, and improve ventilation comfort for patients.

Analysis of influencing parameters of intracavitary laser closure in the treatment of varicose veins of the lower extremities / 国际外科学杂志

Varicose veins of the lower extremities are a common disease in vascular surgery and are the result of multiple factors. The clinical manifestations are mainly thickening, tortuosity and dilation of the superficial veins of the lower extremities, which may be accompanied by discomforts such as lower extremity pain and swelling of the lower legs. In severe cases, skin pigmentation of lower extremities, venous ulcers, etc. The current common treatment options include high saphenous vein ligation and stripping, endogenous laser treatment, radiofrequency ablation and foam sclerotherapy, etc. This article reviews some parameter settings and equipment selection that may affect the therapeutic effect and complications of endogenous laser treatment. Hope to help clinicians better choose the device of intracavity laser closure and find the best possible treatment plan for patients.

Parameters setting of spatial-temporal scan statistics in the study of hand-foot-and-mouth disease cluster / 公共卫生与预防医学

Objective To explore the optimal combination of parameters for the maximum spatial cluster size and maximum temporal cluster size of scan statistics. Methods The daily incidence data of hand-foot-and-mouth disease (HFMD) in Jingzhou in 2016 was collected as data source. The maximum spatial cluster sizes were set to 50%, 40%, 30%, 20%, and 10% of the population at risk. The maximum temporal cluster sizes were set to 7d, 14d, 30d, and 60d. A total of 20 parameter setting schemes were formed and spatial-temporal scanning was conducted one by one. The areas where the number of towns covered by the scanning area was less than 25 were selected, and the clustered epidemic of hand-foot-mouth disease can be detected at the same time in Xiejiaping Town of Songzi City and Sanzhou Town of Jianli County. The combination of large LLR and RR values was the optimal parameter setting. Results When the spatial windows were set to 20% of the population at risk, and the temporal windows were set to 30d, a total of 6 aggregation areas were detected. The number of covered townships was less than 25, and the clustered epidemic of Xiejiaping Township and Sanzhou Town were successfully detected. The LLR and RR values of the detected aggregation area were relatively large. This combination was the optimal parameter setting. Conclusion The combination of different parameters has a significant impact on the results of spatial-temporal scan statistics. It is recommended that parameters be optimized before applying this method.