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The Research Ethics Committee (CEP) has become an essential mechanism for social control in Brazilian research involving human subjects, contributing to the development of studies guided by ethical standards and to the protection of research participants. This article analyzes the performance of CEP in Western Amazonian institution, its history, operating conditions, trends, and different aspects between 2018 to 2022. The theoretical framework addresses the history of research involving human subjects, the origins and evolution of bioethics in the international context, bioethics in Brazil, and regulations on the ethical analysis of research. The data were collected through the Brazil Platform and reports from the institution's CEP. The CEP evaluated 865 research protocols, most of which were from Health Sciences. Additionally, it was observed that during 2018 to 2022 the covid-19 pandemic had a negative impact on the number of projects submitted for evaluation to the CEP. The 57% drop in the number of projects registered during 2020/2022 reveals the negative impact of this event on the execution of projects with human participants.
El Comité de Ética en Investigación (CEP) se ha convertido en un mecanismo esencial para el control social en la investigación brasileña con seres humanos, contribuyendo al desarrollo de estudios guiados por normas éticas y a la protección de los participantes en la investigación. Este artículo analiza el desempeño del CEP en la institución amazónica occidental, su historia, condiciones de funcionamiento, tendencias y diferentes aspectos entre 2018 y 2022. El marco teórico aborda la historia de la investigación con seres humanos, los orígenes y la evolución de la bioética en el contexto internacional, la bioética en Brasil y la normativa sobre el análisis ético de la investigación. Los datos se recogieron a través de la Plataforma Brasil y de informes del CEP de la institución. El CEP evaluó 865 protocolos de investigación, la mayoría de los cuales eran de Ciencias de la Salud. Además, se observó que durante 2018 a 2022 la pandemia de covid-19 tuvo un impacto negativo en el número de proyectos presentados para evaluación al CEP. La caída del 57% en el número de proyectos registrados durante 2020/2022 revela el impacto negativo de este evento en la ejecución de proyectos con participantes humanos.
Os Comitês de Ética em Pesquisa (CEPs) tornaram-se um mecanismo essencial para o controle social em pesquisas brasileiras envolvendo sujeitos humanos, contribuindo para o desenvolvimento de estudos regido por padrões éticos e para a proteção de participantes de pesquisas. Esse artigo analisa o desempenho de CEP em instituição da Amazonia Ocidental, sua história, condições operativas, tendências e diferentes aspectos entre 2018 e 2022. O enquadre teórico visa a história da pesquisa envolvendo sujeitos humanos, as origens e evolução da bioética no contexto internacional, bioética no Brasil e regulamentos de análise ética de pesquisa. Os dados foram coletados através da Plataforma Brasil e relatórios do CEP da instituição. O CEP avaliou 865 protocolos de pesquisa, a maioria deles de Ciências da Saúde. Adicionalmente, foi observado que de 2018 a 2022 a pandemia da covid-19 teve um impacto negativo no número de projetos submetidos para avaliação do CEP. A queda de 57% no número de projetos registrados em 2020/2022 revela o impacto negativo desse evento na execução de projetos com participantes humanos.
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The release of the Measures of Ethical Review of Life Sciences and Medical Research Involving Humans has brought new requirements to the field of ethical review in health management research. Based on the background of new regulations and combining the characteristics of the health management discipline, this paper explored the needs and necessity of ethical review in health management research. In the Measures, the ethical governance of health management research was updated, the concept of exemption from the ethical review was put forward, as well as the importance of protecting the rights and interests of research participants and the protection of personal information were emphasized. This paper also explored the ethical review framework for health management research, including the formulation of operational standards for exemption from ethical review, the refinement of standardized ethical review work systems and processes, and the clarification of information data source verification. These explorations aimed to provide an ethical guarantee for health management research, promote its healthy development, and ensure that the rights and interests of research participants are fully respected and protected. Through research, it is hoped that the ethical level of health management research can be further improved, promoting the development of the discipline and social progress.
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The protection of research participants’ rights and interests is mainly guaranteed through the informed consent system and the ethical review of the Ethics Committee. In practice, some sponsors or researchers misused or mixed legal terms when writing the informed consent forms. More importantly, during the implementation of informed consent by researchers, the phenomenon that insufficient and incomplete notification, and derogation of research participants’ specific rights and interests occurred. This not only affected the scientific nature of the research, but also violated the original intention of clinical trials or medical researchers, and did not fully respect the human dignity and value of research participants. It was urgent for the ethics committee to correct it during the ethical review, and urge the researchers or sponsors to correct and improve it in a timely manner.
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The ethical governance of science and technology has put forward higher ethical requirements for researchers. As important personnel in medical research and front-line workers in contact with patients, clinical health workers should regulate their ethical behavior during the research process and provide informed consent to patients participating in study to protect their rights and interests. At present, patients’ rights and interests are still violated due to insufficient ethical awareness of researchers in the process of clinical research. Ethical governance of science and technology is not only a standard for researchers’ behavior and protection of patients’ rights and interests, but also a new test for scientific research management and ethical review departments, as well as an important measure to enhance the trust between doctors and patients and build harmonious doctor-patient relationship.
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By collecting 475 protocol violation reports of pediatric clinical trials accepted by the ethics committee of a grade A tertiary hospital from January 2016 to December 2022, and conducting classification statistics of the responsible body, types of violation, and natures of violation, this paper analyzed and discussed the specific reasons and response measures for protocol violation. The results showed that the most common types of protocol violation included missed medication and incorrect medication dosage for pediatric research participants, missed laboratory inspection, over-windowed follow-up, and non-compliance with inclusion/exclusion criteria. And the responsibility bodies were pediatric research participants and/or their guardians, followed by the researchers. Besides, the sponsor, clinical trial coordinator, and other factors also contributed to protocol violation. Establishing awareness of responsible body, emphasizing subject management, building sound quality control system, and strengthening ethical supervision are the main countermeasures to prevent and reduce protocol violation in pediatric clinical trials, which helps to protect the safety and rights of pediatric research participants and promote standardized research in pediatric clinical trials.
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【 Objective:】 To understand subjects’ experiences and opinions on clinical trials of traditional Chinese medicine (TCM) and the process of informed consent during the process of participating in TCM clinical trials, and to provide reference for obtaining high-quality informed consent in TCM clinical trials. 【Methods:】 Using qualitative research methods, semi-structured individual in-depth interviews were conducted on 6 participants who had previously participated in TCM clinical trials. 【Results:】 Through data analysis, five major themes and several sub-themes were obtained, including the reasons why participants are willing to participate in TCM clinical trials, the concerns about unwillingness to participate, the information that they hope to be informed during the informed consent process, the specific content that they want to know in TCM clinical trials, and the evaluation of understanding and satisfaction with informed consent. 【Conclusion:】 In the process of informed consent in TCM clinical trials, attention should be paid to the explanation of adverse drug reactions of TCM, the reasonable arrangement and clear notification of the time for participants to participate in the trial, emotional humanistic care in the process of informed consent communication, and the value embodiment of subjects and their expectations for acquiring special knowledge of TCM.
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With the progress of life sciences and medicine and the improvement of laws, regulations and rules, to meet the objective needs and further standardize the ethical review of life sciences and medical research involving humans, it is necessary to refer to international ethical standards to integrate with international standards. On February 18, 2023, the National Health Commission, together with the Ministry of Education, the Ministry of Science and Technology, and the National Administration of Traditional Chinese Medicine, issued the Measures for the Ethical Review of Life Sciences and Medical Research Involving Humans. The scope of this revision is large, the content is more detailed, and many details and specific requirements are added. It expanded the extent of jurisdiction to include colleges and universities, scientific research institutes and other institutions; the scope of review included the field of life sciences; the ethical review and supervision efficiency problems caused by the requirement of multiple departments coordinated supervision required the cooperation of the National Health Commission, the Ministry of Education, the Ministry of Science and Technology, and the National Administration of Traditional Chinese Medicine to strengthen communication and implement supervision. It emphasized the management of conflict of interest, strengthened the protection of privacy and data management, clarified the application of summary procedure review, as well as added the ethical review exemption and the submission of initial review materials, key review content, approval criteria and informed consent content, which improved the operability. It proposed solutions or directions for urgent needs and issues of close concern, allowed commissioned review, strengthened follow-up review, registration and filing, and explored three-level supervision, ethical review collaboration mechanisms, and the construction of regional ethics committees. By continuously improving ethical review and supervision to ensure the safety and rights of research participants, promote the quality of life science and medical research in China, and enhance the international competitiveness of life science and medical research involving humans in China.
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The passing of ethical review is a necessary conditions and prerequisite for the development of life science and medical research involving humans. At present, some medical and health institutions have no or insufficient ethical review capabilities. The lack of ethical review ability has become a bottleneck restricting the development of life science and medical research involving humans. According to documents such as Opinions on Deepening the Reform of the Review and Approval System and Encouraging the Innovation of Pharmaceutical and Medical Devices, Opinions on Strengthening the Ethical Governance of Science and Technology, institutions can entrust competent institutional ethics review committees or regional ethics review committees in writing to conduct ethical review. Entrustment ethical review provides a viable solution for institutions that need to carry out life science and medical research involving humans but do not have an ethics (review) committee or the ethics (review) committee is not competent to review. To conduct the entrustment ethical review, the entrustment between the principal and the trustee is required. According to The Measures for Ethical Review of Life Sciences and Medical Research Involving Humans, if medical and health institutions and their ethical review committees do not accept the formal entrustment to provide the ethical review opinions for other institutions, the local health authorities at or above the county level will impose administrative penalties and sanctions on the relevant institutions and personnel in accordance with the law. Signing the entrustment ethical review contract, implementing legal compliance entrusted ethical review to protect the rights and interests of the trustee and the principal, and protect the research participants.
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【Objective:】 To analyze the emotional status and follow-up status of the participants in the drug clinical trials in a hospital during the epidemic prevention and control, with a view to maximizing the protection of participants’ rights and interests under special circumstances. 【Methods:】 The general information, depression screening scale (PHQ-9), anxiety screening scale (GAD-7) and subject compliance assessment scale were completed online by participants with gold data questionnaire. At the same time, the status of drug clinical trials under study and the follow-up status of participants under study were collected from November 1, 2021 to December 8, 2021 and from December 9, 2021 to January 24, 2022. Excel software and SPSS18.0 software were used for data statistics and analysis. 【Results:】 During the epidemic prevention and control, there were 20 drug clinical trial projects under way in the hospital. From December 9, 2021 to January 24, 2022, the planned number of visits was 161, and the actual number of visits to the hospital was 84 (52.2%). Plus 24 participants who mailed drugs, the overall visit rate was 67.1%, among which the visit rates of oral drugs, non-oral drugs, and oral drugs combined with non-oral drugs were 79.3%, 71.9%, and 41.0% respectively. From November 1, 2021 to December 8, 2021, the planned number of visits was 166, the actual number of visits to the hospital was 157 (94.6%), and the number of telephone visits accounted for 1.8% of the total planned number of visits. The number of participants who did not take the drug and those who delayed taking the drug were both 0. The total compliance of participants was as high as 80.0%. A total of 40 valid questionnaires were retrieved, and the detection rates of depression and anxiety were 42.5% and 30.0% respectively. 【Conclusion:】 The epidemic prevention and control has a large short-term impact on the follow-up of the participants under study. The formulation of relevant follow-up measures and the conduction of classification management can not only improve the emotions of the participants to a certain extent, but also protect the rights and interests of participants, providing suggestions for the follow-up of participants under emergencies in the future.
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Cognitive impairment (CI) is no longer considered a normal and inevitable change of aging. This study was carried out to assess extent, spectrum, and predictors of cognitive impairment in the participants. Acommunity?based cross?sectional study was done on 616 urban geriatric participants of Varanasi city selected by multistage sampling procedure. The participants were interviewed about their sociodemographic profile using a predesigned and pretested pro forma, and their cognition was assessed through Mini-Mental State Examination tool. Logistic regression analysis was applied for an inferential purpose. Adjusted odds ratios (AORs) and 95% confidence interval were computed. Extent of cognitive impairment in geriatric participants was 22.4%. AORs were maximum in ?80 years (21.23; 95% Confidence Interval: 7.05–63.94), in illiterate and just literate participants (13.71; 95% Confidence Interval: 6.49–28.98) and in homemakers (17.0; 95% Confidence Interval: 4.28–67.49). Nine out of 40 urban geriatric participants had cognitive impairment. Adversities of cognitive impairment were more with advancing age, nonengagement in gainful employment, and low literacy levels.
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Abstract Objective To identify the barriers to provide to women and adequately train physicians on therapeutic abortions in public hospitals in Peru. Methods Descriptive cross-sectional survey-based study. We invited 400 obstetrics and gynecology specialists from 7 academic public hospitals in Lima and 8 from other regions of Peru. Expert judges validated the survey. Results We collected survey results from 160 participants that met the inclusion criteria. Of those, 63.7% stated that the hospital where they work does not offer abortion training. Most of the participants consider that the position of the Peruvian government regarding therapeutic abortion is indifferent or deficient. The major limitations to provide therapeutic abortions included Peruvian law (53.8%), hospital policies (18.8%), and lack of experts (10.6%). Conclusion Most surveyed physicians supported therapeutic abortions and showed interest in improving their skills. However, not all hospitals offer training and education. The limited knowledge of the physicians regarding the law and institutional policies, as well as fear of ethical, legal, and religious repercussions, were the main barriers for providing abortions.
Resumo Objetivo Identificar as barreiras para oferecer às mulheres e capacitar adequadamente os médicos sobre abortos terapêuticos nos hospitais públicos do Peru. Métodos Estudo descritivo transversal baseado em inquérito. Convidamos 400 especialistas em obstetrícia e ginecologia de 7 hospitais públicos acadêmicos de Lima e 8 de outras regiões do Peru. Juízes especialistas validaram a pesquisa. Resultados Coletamos os resultados da pesquisa de 160 participantes que atenderam aos critérios de inclusão. Destes, 63,7% afirmaram que o hospital onde trabalham não oferece treinamento sobre aborto. A maioria dos participantes considera que a posição do governo peruano em relação ao aborto terapêutico é indiferente ou deficiente. As principais limitações para fornecer abortos terapêuticos incluem a lei peruana (53,8%), políticas hospitalares (18,8%) e falta de especialistas (10,6%). Conclusão A maioria dos médicos pesquisados apoiava o aborto terapêutico e demonstrava interesse em aprimorar suas habilidades. No entanto, nem todos os hospitais oferecem treinamento e educação. O conhecimento limitado dos médicos sobre a lei e as políticas institucionais, além do medo de repercussões éticas, legais e religiosas, foram as principais barreiras para a realização do aborto.
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Humanos , Feminino , Gravidez , Peru , Aborto Espontâneo/tratamento farmacológico , Educação Médica , Fortalecimento Institucional , Ginecologista , Hospitais PúblicosRESUMO
One of the health problems which is associated during the management of a patient with series of drugs is ADR/ADE. Therefore, the aim of the present study was to find out the activities for improving the reporting of ADRs/ADEs. The data on the KAP is collected on a pre-tested questionnaire.METHODSThis is a non-interventional cross-sectional study. The questionnaire was prepared after referring the questionnaires of previous studies. Out of 120 questionnaires distributed, only 100 questionnaires were received back. Descriptive statistics is used for analysing the data.RESULTSThe response on the questionnaire is 83.3%. Seventy-nine (79) participants knew the definition of ADR/ADE. Eighty-eight (88) participants want to report the ADRs of the marketed drugs irrespective of new or old. Seventy-five (75) participants know about PvPI. Ninety (90) participants do not consider all the OTC and Herbal drugs are safe. Seventy-two (72) participants do not know the establishment of a Pharmacovigilance centre at the Department of Pharmacology, JNIMS. Only 55.6% of the participants oblige to report the ADRs as a professional health care provider. 58% of the participants opine to conduct a regular CME program on ADR/Pharmacovigilance. 63.2% participants state that maximum ADRs are seen among dermatological, paediatric and elderly patients. 58.2% of the participants express their opinion about the occurrence of ADRs/ADEs with irrational prescription, polypharmacy, foods, drinks etc. 44% participants have the attitude of reporting ADRs/ADEs but only 10% participants perform the actual reporting with careful observations on patients’ behaviour. Most of the ADRs/ADEs are avoidable if there is good communication and reporting.CONCLUSIONSA regular awareness programme on ADR/ADE along with CME program and also online reporting facilities is necessary for promotion of reporting of the ADR/ADE. Therefore, the drug should be prescribed rationally, and polypharmacy should be avoided as much as possible.
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Objective To explore a kind of visual evoked potential test equipment and method that is more suitable for the application of forensic clinical visual acuity evaluation. Methods Thirty-four volunteers (68 eyes) were selected, including 15 males and 19 females, aged between 20 and 40 years. Test lenses were placed before the tested eyes of volunteers to induce refractive myopia with insert method, and the diopter lenses were adjusted so that the visual acuity level of one eye of volunteers was above 0.8, and the visual acuity of the other eye was at moderate damage level (<0.3 and ≥0.1). The tests were carried out under the binocular simultaneous asynchronous stimulation mode (hereinafter referred to as "binocular mode") and monocular separate stimulation mode (hereinafter referred to as "monocular mode") of virtual reality-pattern visual evoked potential (VR-PVEP), and the amplitude of PVEP of volunteers under the two modes was compared at four spatial frequencies of 8×8, 16×16, 24×24 and 32×32. Results The differences in the amplitude of P100 wave between monocular and binocular modes at 8×8 spatial frequency had no statistical significance and the differences in amplitude of P100 wave between monocular and binocular modes at 16×16, 24×24, and 32×32 spatial frequencies had statistical significance (P<0.05). The amplitude of the same eye in monocular mode was higher than that in binocular mode. Through correlation analysis, it was found that the amplitude of P100 wave in monocular mode was moderately correlated with amplitude of P100 wave in binocular mode. Conclusion In forensic identification practice, VR-PVEP is helpful for overcoming the disturbance of poor fixation, and to increase the reliability of PVEP evaluation results. It can greatly shorten the detection time of PVEP and improve work efficiency.
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Adulto , Feminino , Humanos , Masculino , Adulto Jovem , Potenciais Evocados Visuais , Olho , Reprodutibilidade dos Testes , Realidade Virtual , Acuidade VisualRESUMO
O objetivo deste estudo passou pela análise da qualidade dos serviços e a consequente intenção de recomendação da corrida de São. João de Braga e da região de Braga, como destino turístico, por parte dos participantes. A amostra foi de 284 participantes, tendo sido usado um instrumento que já foi utilizado noutros estudos desta mesma temática. Para analisar os dados e verificar a relação existente entre as variáveis foram realizados testes de regressão linear múltipla. Os principais resultados evidenciaram o processo de acreditação e o kit de participação como preditores estatisticamente significativos ao nível das intenções de recomendação da corrida e o processo de acreditação e a paisagem circundante para as intenções de recomendação da região. Posto isto, aquando da avaliação da qualidade dos serviços, destaca-se o processo de acreditação, uma vez que é um preditor comum das intenções de recomendação do evento e da região.
The aim of this study was to analyze the quality of services and the consequent intention of recommending the race of São João de Braga and the region of Braga, Portugal, as a tourist destination, by the participants. The sample consisted of 284 participants, using an instrument that has already been used in other studies of this same subject. To analyze the data and verify the relationship between the variables, multiple linear regression tests were performed. The main results evidenced the accreditation process and the participation kit as statistically significant predictors in the intentions of the race recommendation and the accreditation process and the surrounding landscape for the region's recommendation intentions. In conclusion, when assessing the quality of services, the accreditation process stands out, since it is a common predictor of the intentions of the event and the region
El objetivo de este artículo es analizar la calidad de los servicios y la consecuente recomendación de la carrera de São João de Braga y la región de Braga, Portugal, como destino turístico, por parte de los participantes. Una muestra de 284 participantes, se usó un instrumento ya utilizado de otros instrumentos de estudio de la temática. Para análisis de datos y verificación de la relación existente, se han realizado varios ensayos de regresión lineal. Los principales resultados son la evidencia o el proceso de acreditación y el kit de participación como predictores estadísticamente significativos a lo largo de las intenciones de recomendación y el proceso de acreditación y la distribución de datos para las intenciones de recomendación. En conclusión, el aval da evaluación da calidad dos servicios, destaca-se el proceso de acreditación, es posible que sea su predictor común das intenciones de recomendación do evento y da región.
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BACKGROUND@#We reported that human T cell leukemia virus 1 (HTLV-1) infection is positively associated with atherosclerosis. Recent evidence has revealed a close association of periodontitis with atherosclerosis, endothelial dysfunction, and disruption of the microcirculation. However, the association between HTLV-1 and advanced periodontitis has not been investigated to date. Since hematopoietic activity is closely linked to endothelial maintenance activity and is known to decline with age, we hypothesized that the state of hematopoietic activity influenced the association between HTLV-1 and advanced periodontitis in elderly participants.@*METHODS@#A cross-sectional study was performed including 822 elderly participants aged 60-99 years who participated in a dental health check-up. Advanced periodontitis was defined as a periodontal pocket ≥ 6.0 mm. Participants were classified as having low or high hematopoietic activity according to the median values of reticulocytes.@*RESULTS@#HTLV-1 infection was positively related to advanced periodontitis among participants with lower hematopoietic activity (lower reticulocyte count), but not among participants with higher hematopoietic activity (higher reticulocyte count). The adjusted odds ratio (95% confidence interval) considering potential confounding factors was 1.92 (1.05-3.49) for participants with a lower reticulocyte count and 0.69 (0.35-1.36) for participants with a higher reticulocyte count.@*CONCLUSIONS@#Among elderly participants, the association between HTLV-1 infection and advanced periodontitis is influenced by hematopoietic activity. Since hematopoietic activity is associated with endothelial maintenance, these findings provide an efficient tool for clarifying the underlying mechanism of the progression of periodontitis among elderly participants.
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Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Transversais , Infecções por HTLV-I , Hematopoese , Fisiologia , Vírus Linfotrópico T Tipo 1 Humano , Fisiologia , Japão , Epidemiologia , Razão de Chances , Periodontite , Epidemiologia , Virologia , Prevalência , Fatores de RiscoRESUMO
Background: Disaster causes widespread destruction, disrupting people’s lives and causing human suffering with communities finding it difficult to cope. When the disaster occurs, human beings may not have the power to stop it from occurring, nevertheless they may have the power and ability to adapt or minimize the impact of the disaster on their lives. This study was aimed to assess the level of knowledge and awareness on disaster management among medical professionals.Methods: A cross-sectional study was conducted among the medical professionals from two selected medical college hospitals in Dhaka city of Bangladesh from January to April 2017. A total of 120 samples were selected purposively using two stages sampling technique. The data was collected using self-administered semi-structured questionnaire and was analysed using SPSS 20.0 version.Results: In this study half 60 (50.0%) of the study participants were in the age group 20-30 years and about 77.5% of the study participants were Muslims. About 64.2% of the study participants had less than 11 years of professional experience. Only 10 (8.3%) of the study participants had attended training on disaster management. About 30.0% of the study participants had good level of knowledge and only 49.2% had high level of awareness.Conclusions: The findings revealed that most of the study participants had not attended any training on disaster management. It also reported that the majority of the study participants had poor level of knowledge. Evacuation exercises need to be done for the entire hospital at least twice a year.
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Purpose: The aim of the study was to describe the clinical features and treatment outcomes of vasoproliferative tumors (VPT) in Indian participants. Methods: This study design was a retrospective case series in a tertiary eye care center. Case records of patients diagnosed with VPT from 2011 to 2015 were reviewed, and their demographic details, clinical presentation, and treatment outcomes were documented. Baseline and follow-up visual acuity and tumor dimensions were statistically compared by applying paired t-test. Statistical analysis used SPSS version 14. Results: Twenty-two tumors from 19 eyes of 17 patients were included. Mean age at presentation was 43.5 years (range: 15� years). Mean presenting best-corrected visual acuity (BCVA) was + 1.10 logMAR. Sixty-eight percent eyes had secondary tumors. Most common association of secondary VPT was Coats disease followed by retinal vasculitis, polypoidal choroidal vasculopathy, familial exudative vitreoretinopathy, and traumatic chorioretinopathy. Ten tumors (45%) involved the inferior quadrant. Tumor-associated features were intra/subretinal exudates, vitritis, subretinal fluid, vitreous hemorrhage, preretinal fibrosis, epiretinal membrane, and subretinal blood. Treatment included cryotherapy, intravitreal or oral steroids, laser photocoagulation, cryotherapy with encirclage, cryotherapy with anti-vascular endothelial growth factor, and observation. Complications included tumor recurrence, retinal detachment, raised intraocular pressure, neovascularization of iris, and cataract. Ninety-five percent VPT regressed at mean 21 months (Median: 17 months; Range: 3� months). Mean final BCVA was + 1.21 logMAR. Conclusion: VPTs are commonly unilateral, unifocal, and located anterior to equator in inferior fundus. Secondary tumors are more common than primary tumors. Treatment achieves tumor regression in majority of cases.
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Objective Currently,the sit-to-stand process is not well evaluated.The aim of the study is to evaluate quantitatively the reliability of posturographic parameters in the sit-to-stand process.Methods Seventy-four healthy participants were enrolled and required to finish 20-second sitting,standing and the sit-to-stand process.The computer calculated the posturographic parameters automatically.The test was repeated twice to assess the reliability at an interval of six days.Results During sitting and standing position,the intraclass correlation coefficients (ICCs) of all the parameters were above 0.50,indicating a good or fair reliability.During the standing stance and sitting phase of the sit-to-stand process,the ICCs of all the parameters were above 0.40 and 0.60 respectively,showing a good or fair reliability.Conclusions Sit-to-stand posturographic parameters are a new way to assess the position control ability among the healthy participants with a good reliability.Further study should be conducted among patients to result in better functional and effectiveness evaluation.
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O movimento de Reforma Psiquiátrica trouxe a necessidade de reestruturar os serviços de assistência em saúde mental e para tal a avaliação torna-se prioritária para prestar uma assistência integral e humanizada. Diante desse contexto e considerando que a população brasileira é constituída em sua maioria por negros (pretos e pardos), é fundamental que todas as pesquisas em saúde tenham um recorte racial, a começar pela inserção do quesito raça cor. Desta forma identificando o perfil e as peculiaridades dessa população, garantindo assim a qualidade da assistência com a utilização dos dados encontrados no processo de avaliação. Estudo de caráter descritivo, exploratório e transversal, teve como objetivo: comparar variáveis sociodemográficas relacionadas ao cuidado recebido dos usuários atendidos em CAPSad nos estados AP, MG e SP quanto ao quesito raça/cor. Foram entrevistados 707 usuários atendidos em CAPSad nos estados AP, MG e SP Para o presente estudo foram utilizados: os seguintes instrumentos um questionário de dados sociodemográficos, a Escala de Satisfação SATIS-BR e a Escala de Avaliação da Percepção de Mudança (EMP). Este estudo constatou as seguintes características de variáveis sociodemográficas: predominância da população masculina (57,3%), que se autodeclararam negros (59,4%), solteiros (59,0%), com faixa etária média de 44 anos, sendo o emprego a principal fonte de renda (31,7%) e com renda familiar de até 2 salários mínimos (71,1%). Quanto à escolaridade, apesar de 94,3% saberem ler, a maioria (38,8%) tinham apenas o ensino fundamental incompleto, e somente 5,1% da amostra deste estudo apresentavam nível superior completo ou acima. Os resultados apontaram que sobre o tempo de permanência no serviço os não negros tem 1,7 mais chances de ficarem mais de 6 meses no CAPSad que os negros, controlado os efeitos de alfabetização, escolaridade e renda. Sobre internação os não negros tem 1,6 mais chances de terem sido internados antes do tratamento no CAPS ad que os negros, controlado os efeitos de alfabetização, escolaridade e renda, sobre a visita domiciliar os negros tem 2,4 mais chances de receberem visita que os não negros, controlados os efeitos de alfabetização, escolaridade e renda. Identificou também que negros e não negros estão igualmente satisfeitos e com a mesma percepção de mudança.
The psychiatric reform movement resulted in the restructuring process of metal health services, which aims to provide integral and humanized assistance, prioritizing the evaluation. Given this context and considering that the population in Brazil is made up mostly of black and pardo people, it is essential that every health research consider all the racial aspects, starting with race color. Therefore, it is possible to identify the profile and peculiarities of a certain population, guaranteeing the quality of assistance services offered through the data obtained in the evaluation process. The study made with descriptive, explanatory and transversal aspects, had as a goal to compare sociodemographic variants related to the care offered to the user of Psychosocial Care Center for Alcohol and Drugs (CAPSad), in the states of Amapa (AP), Minas Gerais (MG) and Sao Paulo (SP), considering race/color. 707 users of CAPSad were interviewed in the states of AP, MG and SP. In the study the following instruments were used: a socio demographic questionnaire, the Satisfaction Scale (SATIS-BR), the Scale of Perceived Change (EMP). The sociodemographic variants were characterized by: a larger male population (57,3%), which (59,4%) is self-denominated black, (59,0%) single, with the majority being in the 44 years old range, with the job as main source of income (31,7%), and with a family income equivalent to two times the value of the Brazilian minimum wage (71,1%). As for schooling, while 94,3% can read, the majority (38,8%) didnt complete their basic education, and only 5,1% graduated from college. The results revealed that 1,7 of non-black participants are more likely to be more than 6 months in the CAPSad than the black participants, where the effects of literacy, schooling and income are under control. About hospitalization, non-black participants have 1,6 more chances of being hospitalized before the treatment at the CAPSad than the black participants, where the effects of literacy, schooling and income are under control. About homecare visits (VD), the black participants have 2,4 more change to receive VD than the non-black participants, where the effects of literacy, schooling and income are under control. It was determined that black participants and non-black participants are equally satisfied and have the same perception of change.
Assuntos
População Negra , Urticária Solar , Enfermagem , Serviços de Saúde MentalRESUMO
Background: Syphilis is a sexually transmitted infection caused by Treponema pallidum. The disease becomes very common among individuals with multiple sexual partners without protection. Aim: This research aimed at assessing the prevalence of syphilis infection in Cape Coast Metropolis and the factors associated with the transmission of the disease Methodology: 200 participants from Cape Coast were sampled and assessed for syphilis infection using Venereal Disease Research Laboratory syphilis test strips (a nontreponemal test) and positive samples were confirmed with Treponema palladium haemagglutination (TPHA) test. Questionnaires, reflecting the participant’s sociodemographic data were also administered. The results were analysed, to assess the relationship between various risk factors and syphilis infection. Results: The prevalence of syphilis infection in Cape Coast was found to be 8.5%, mainly associated with participants having multiple sexual partners and having unprotected and indiscriminate sex. Other factors found to be indirectly affecting the rate of infection were illiteracy, lack of knowledge and information concerning the disease. Conclusion: The seroprevalence of syphilis infection in the Cape Coast Metropolis is an indication that the disease is endemic.