The effect of preperitoneal pelvic packing for hemodynamically unstable patients with pelvic fractures / 中华创伤杂志(英文版)

PURPOSE@#Hemodynamically unstable patients with pelvic fractures still represent a challenge to trauma surgeons and have a very high mortality. This study was designed to explore the effect of the interventions of direct preperitoneal pelvic packing for the hemodynamically unstable pelvic fractures.@*METHODS@#This retrospective study enrolled 67 cases of severe pelvic fractures with unstable hemodynamics from October 2011 to December 2019. All patients presented in our emergency center and received preperitoneal pelvic packing were included in this study. The indication was persistent systolic blood pressure ≤90 mmHg during initial resuscitation and after transfusion of two units of red blood cells. Patients with hemodynamic stability who need no preperitoneal pelvic packing to control bleeding were excluded. Their demographic characteristics, clinical features, laboratory results, therapeutic interventions, adverse events, and prognostic outcomes were collected from digital information system of electronic medical records. Statistics were described as mean ± standard deviation or medium and analyzed using pair sample t-test or Mann-Whitney U-test.@*RESULTS@#The patients' average age was 41.6 years, ranging from 10 to 88 years. Among them, 45 cases were male (67.2%) and 22 cases were female (32.8%). Significant difference was found regarding the systolic blood pressure (mmHg) in the emergency department (78.4 ± 13.9) and after preperitoneal pelvic packing in the surgery intensive care unit (100.1 ± 17.6) (p < 0.05). Simultaneously, the arterial base deficit (mmol/L) were significantly lower in the surgery intensive care unit (median -6, interquartile range -8 to -2) than in the emergency department (median -10, interquartile range -14 to -8) (p < 0.05). After preperitoneal pelvic packing, 15 patients (22.4%) underwent pelvic angiography for persistent hypotension or suspected ongoing haemorrhage. The overall mortality rate was 29.5% (20 of 67).@*CONCLUSIONS@#Preperitoneal pelvic packing, as a useful surgical technique, is less invasive and can be very efficient in early intra-pelvic bleed control.

Clinical perspective: caesarean hysterectomy for placenta accreta spectrum and role of pelvic packing

Caesarean hysterectomy (CH) is considered the gold standard for management of morbidly adherent placenta, now termed as placenta accreta spectrum (PAS). If bleeding is not controlled following removal of uterus, it is sometimes necessary to pack the pelvis and continue monitoring with correction of bleeding and physiological parameters in operating room and intensive care unit. This now comes under the damage control approach, being driven primarily by abnormal physiology rather than anatomical reconstruction. The pelvic packs are removed after about 48 hours. This retrospective study was done in patients with antenatal diagnosis of PAS who required CH, comparing those who required pelvic packing with those who did not. The variables compared were pre-operative (clinical and radiological), intra-operative (duration of surgery, blood loss and transfusion requirements of whole blood and blood products), and the final histopathological diagnosis. Outcome variables in terms of duration of hospital stay, re-admissions, re-laparotomy and complications were also compared. Over two years, three of eight patients with PAS required pelvic packing following CH. There were no differences between the two patient groups with any of the predictor variables or outcomes other than requirement of blood products. This suggests pelvic packing is a safe and efficacious procedure in intractable haemorrhage following CH for PAS. Pelvic packing needs greater awareness amongst obstetricians as the incidence of PAS is likely to increase.

Effect of angioembolisation versus surgical packing on mortality in traumatic pelvic haemorrhage: A systematic review and meta-analysis / 世界急诊医学杂志（英文）

BACKGROUND: The management of complex pattern of bleeding associated with pelvic trauma remains a big chalenge for trauma surgeons. We aimed to conduct a comprehensive meta-analysis to compare the outcomes of angioembolisation and pelvic packing in patients with pelvic trauma. METHODS: We conducted a systematic search of electronic information sources, including MEDLINE; EMBASE; CINAHL; the CENTRAL; the World Health Organization International Clinical Trials Registry; ClinicalTrials.gov; ISRCTN Register, and bibliographic reference lists. The primary outcome was defined as mortality. Combined overall effect sizes were calculated using random-effects models. Results are reported as the odds ratio (OR) and 95％ confidence interval (CI). RESULTS: We identified 3 observational studies reporting a total of 120 patients undergoing angioembolisation (n=60) or pelvic packing (n=60) for pelvic trauma. Reporting of the Injury Severity Score (ISS) was variable, with higher ISS in the pelvic packing group. The risk of bias was low in two studies, and moderate in one. The pooled analysis demonstrated that angioembolisation did not significantly reduce mortality in patients with pelvic trauma compared to surgery (OR=1.99; 95％CI= 0.83–4.78,P=0.12). There was mild between-study heterogeneity (I2=0％, P=0.65). CONCLUSION: Our analysis found no significant difference in mortality between angioembolisation and pelvic packing in patients with traumatic pelvic haemorrhage. The current level of evidence in this context is very limited and insufficient to support the superiority of a treatment modality. Future research is required.

Cirugía de control de daños en hemorragia obstétrica: experiencia institucional / Damage control surgery in obstetric hemorrhage: institutional experience

Resumen OBJETIVO: evaluar los resultados de la cirugía de control de daños en hemorragia obstétrica en un hospital de tercer nivel. MATERIAL Y MÉTODO: estudio retrospectivo, descriptivo y transversal efectuado en pacientes con hemorragia obstétrica que requirieron cirugía de control de daños en el Hospital de Ginecoobstetricia 3 del Centro Médico Nacional La Raza, de enero a diciembre del 2015. Para el análisis estadístico se utilizaron medidas de tendencia central y el programa SPSS, versión 16.0. RESULTADOS: se identificaron 16 pacientes con edad promedio de 34.5 años, y 33.3 semanas de gestación. La causa de la hemorragia fue: atonía uterina 31%, inserción placentaria anómala 44%, ruptura uterina 13%, otras 13%. La cirugía inicial fue programada en 6%, y de urgencia en 94%. El promedio de compresas fue de 7.6, y de ligadura de arterias hipogástricas 88%. El tiempo promedio entre la primera y segunda cirugía fue de 27.3 horas. En 81% de los casos se logró el tratamiento definitivo en la segunda cirugía. Los días de estancia en la unidad de cuidados intensivos fueron 5.3, y de estancia hospitalaria 10.9. Hubo complicaciones en 81% de los casos y las principales complicaciones quirúrgicas representaron 63%, las infecciosas 31% y las renales 81%. Se documentó una muerte materna. CONCLUSIONES: si no se consigue el control definitivo del sangrado la cirugía de control de daños debe efectuarse lo más pronto posible. En Obstetricia hay un elevado porcentaje de complicaciones quirúrgicas, infecciosas y derivadas de la hemorragia masiva.

Abstract OBJECTIVE: To evaluate the results of the damage control surgery in obstetric hemorrhage in a third level hospital. MATERIAL AND METHOD: Retrospective study. Medical records from patients with obstetric hemorrhage who required damage control surgery at the Obstetrics and Gynecology hospital number 3, "Centro Médico Nacional La Raza", a third level unit in Mexico city, from January to December 2015. Measures of central tendency were performed for the statistical analysis using Software SPSS, version 16.0. RESULTS: 16 patients were identified. The mean age of the participants was 34.5 years and for the gestational age was 33.3 weeks. The etiology of the hemorrhage included: uterine atony in 31%, abnormal placentation in 44%, uterine rupture in 13%, other causes in 13%. Planned programmed surgery was performed in 6%, while emergency surgery in 94%. The mean number of compress towels used was 7.6, and hypogastric arteries ligation was necessary in 88%. The mean time between the first and second surgeries was 27.3 hours. A definitive treatment was achieved at the second surgery in 81% of cases. The mean time of ICU stay was 5.3 days, and in hospital was 10.9 days. Complications were identified in 81% of cases, being the principal: surgical (63%), infectious (31%) and renal (81%). One death was documented. CONCLUSIONS: Damage control surgery should be done early by not achieving definitive control of bleeding. In obstetrics there is a high percentage of surgical complications, infectious and those resulting from massive hemorrhage.

Preperitoneal Pelvic Packing Prior to Pelvic Angiography in Patients with Hemodynamic Instability due to Severe Pelvic Fracture: Two Cases

The mortality of patients with hemodynamic instability due to severe pelvic fracture is high despite multidisciplinary management. Current management algorithms for these patients emphasize pelvic angioembolization (AE) for hemorrhage control. However, a surgical procedure is often needed because AE is time-consuming and approximately only 15% of patients have arterial bleeding. Most hemorrhages from severe pelvic fracture originate from venous or bone injury. Current research demonstrates the effectiveness of preperitoneal pelvic packing (PPP) in hemorrhage control. However, there are no reports of its use in Korea. Accordingly, we present our early experiences of PPP for control of hemorrhage due to severe pelvic fracture in a trauma center in Korea.

Evolving Frontiers in Severe Polytrauma Management – Refining the Essential Principles

This editorial aims to refine the severe polytrauma management principles. While keeping ABCDE priorities, the termination of futile resuscitation and the early use of tourniquet to stop exsanguinating limb bleeding are crucial. Difficult-airway-management (DAM) is by a structured 5-level approach. The computerised tomography (CT) scanner is the tunnel to death for hemodynamically unstable patients. Focused Abdominal Sonography for Trauma–Ultrasonography (FAST USG) has replaced diagnostic peritoneal lavage (DPL) and is expanding to USG life support. Direct whole-body multidetector-row computed tomography (MDCT) expedites diagnosis & treatment. Non-operative management is a viable option in rapid responders in shock. Damage control resuscitation comprising of permissive hypotension, hemostatic resuscitation & damage control surgery (DCS) help prevent the lethal triad of trauma. Massive transfusion protocol reduces mortality and decreases the blood requirement. DCS attains rapid correction of the deranged physiology. Mortality reduction in major pelvic disruption requires a multi-disciplinary protocol, the novel pre-peritoneal pelvic packing and the angio-embolization. When operation is the definitive treatment for injury, prevention is best therapy.

Packing pelviano retroperitoneal en fracturas inestables de pelvis: reporte de un caso y descripción de la técnica / Retroperitoneal packing in unstable pelvic fractures: case report and description of the technique

Pelvic fractures in hemodynamically unstable patients are associated with high rates of morbidity and mortality. The optimal management strategy for hemorrhage control remains controversial. We present a clinical case that was successfully treated with retroperitoneal pelvic packing. The technique is described and discussed.

Las fracturas de pelvis con inestabilidad hemodinámica se asocian a altas tasas de morbilidad y mortalidad. No existe consenso sobre la mejor manera de controlar hemorragia asociada. Se presenta un caso manejado exitosamente mediante la realización de un packing pelviano retroperitoneal. Se describe la técnica quirúrgica y se discuten sus alcances.