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Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. This study is about the etiological and clinical profile of paroxysmal, persistent and permanent AF. Aim: The aim of this article was to review the clinical epidemiological features of atrial fibrillation. Materials and methods: A hospital-based descriptive study was conducted among 50 patients, diagnosed as atrial fibrillation in Cardiology Department, from 2016 to 2017. Results: Out of 50 patients with atrial fibrillation, 32% were aged between 60 – 69 years and 42(84%) were females and 8 (16%) were males. Permanent AF was seen in 56% patients. Conclusions: Palpitation followed by dyspnoea was the major symptoms encountered with atrial fibrillation, and in females within the age group of 50 years and above are prone to develop AF.
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Absrtact: Object vie To observe the INR of AF hyperuricemia patients 'prothrombin time under the situation where both allopurinol and warfarin are used to the treatment of anticoagulation . Methods A total of 240 patients with chronic permanent AF hyperuricemia were collected and then divided randomly into two groups:warfarin treatment group(120 cases), to maintain the original dose warfarin therapy and keep a low-purine diet;and the combined treatment group (120 cases), also in the conventional warfarin antithrombotic therapy and a low-purine diet, on this basis, plus allopurinol 100 mg, three times a day, which last for two weeks .Then observing and examining the change of the two group's INR after the treat-ment. Results The INR of the combined treatment group was obviously higher than the warfarin group ( P<0 .05 ) . Conclusion Allopurinol can increase antithrombotic effect of warfarin .INR should be monitored regularly during the treatment so as to adjust warfarin dosage accordingly .