In-Vitro Anthelmintic Activity of Croton Bonplandianum Baill.

The aim of present study was to evaluate anthelmintic activity of aqueous, ethanolic and petroleum ether extracts of leaves of croton bonplandianium baill using earthworms. Various concentrations i.e.20, 40,and 60mg/ml of above mentioned extracts were tested in bioassay which involves determination of time of paralysis( P) and time of death(D) worms. Albendazole of same concentration was included as standard reference of normal saline solution as control. The results of present study indicated that the ethanolic and petroleum ether extracts of Croton bonplandianum shows significantly Anthelmintic activity when compared to the reference Albendazole drug. In conclusion the traditional use of leaves of plant Croton bonplandianum as an anthelmintic have been confirmed.

In vitro anthelmintic activity of the whole plant of enicostemma littorale by using various extracts.

Development of anthelmintic resistance and high cost of conventional anthelmintic drugs led to the evaluation of medicinal plants has an alternative source of anthelmintics.In the current study, experiments were conducted to evaluate the possible anthelminitic effects of various extracts of the whole plant of Enicostemma littorale. Various concentrations (25, 50,100,200mg/ml) of all extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. Albendazole was used as a reference standard and saline as a control group. Dose dependent activity was observed in all extracts Enicostemma littorale.