RESUMO
Objective: To investigate the chemical constituents in the ethyl acetate extract from Physalis alkekengi var. franchetii. Methods: The chemical constituents were isolated by silica gel, Sephadex LH-20, and ODS column chromatographies. Their structures were elucidated on the basis of physicochemical properties and spectral data. Results: These compounds were identified as 4, 7-didehydroneophysalin B (1), 4′-methoxy kaemferol (2), physalin O (3), 25, 27-dihydro-4, 7-didehydro-7-deoxyneophysalin A (4), physalin G (5), p-couramic acid (6), physalin E (7), 4, 7-didehydrophysalin B (8), physalin D (9), 6, 6′, 7, 7′-tetrahydroxy-5, 5′-bicoumarin (10), and luteolin-7-O-α-D-glueopyranosid (11). Conclusion: Compounds 10 and 11 are isolated from the plants in family Solanaceae for the first time. Compound 6 is firstly reported from the plants of Physalis L., and compounds 2 and 8 are obtained from this species for the first time.
RESUMO
Objective: To investigate the chemical constituents in persistent calyx of Physalis alkekengi var. franchetii. Methods: Various colume chromatographies over silica gel, Sephadex LH-20, and HPLC were used to separate the chemical constituents and their structures were elucidated by physicochemical property, 1H-NMR, 13C-NMR, and MS. Results: Four chemical constituents were obtained and identified as caffeic acid ethyl ester (1), 25, 27-dehydro-physalin L (2), physalin D (3), and cuneataside E (4). Conclusion Compound 2 is a new natural product, and compound 4 is isolated from the plant for the first time.
RESUMO
Objective To study the active constituents of Physalis alkekengi var. franchetii MethodsThe compounds were separated by silica gel and Sephadex LH-20 chromatography method, their structures were identified on the spectral analyses and physical data. Results Eleven compounds were isolated and identified as ?-sitosterol (Ⅰ), physalin A (Ⅱ), physalin B (Ⅲ), physalin O (Ⅳ), physalin L (Ⅴ), physalin M (Ⅵ), daucosterol (Ⅶ), ombuine (Ⅷ), 5, 4′, 5′-trihydroxy-7, 3′-dimethoxy-flavonol (Ⅸ), luteolin (Ⅹ), and luteolin-7-O-?-D-glucopyranoside (Ⅺ). Conclusion Compound Ⅸ is a new compound named physaflavonol.