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Introducción: El nevus de Ota es un hamartoma melanocítico dérmico benigno de aspecto macular, mal delimitado y en parche de color negrogrisáceo que generalmente afecta unilateralmente la primera y segunda rama del trigémino. Objetivo: Evaluar la eficacia, seguridad y los eventos adversos ocasionados por la aplicación de láser Alexandrita de 755 nm para el tratamiento del nevus de Ota. Métodos: Serie de casos de 10 pacientes de fototipo IV con Nevus de Ota unilateral atendidos entre enero 2017 y diciembre 2018, los cuales fueron tratados con esta energía lumínica y con parámetros definidos. Resultados: La media de edad fue de 29 años., Los pacientes que completaron el tratamiento no presentaron repigmentación en la lesión tratada y el índice de satisfacción fue aceptable. Se observó que el promedio de sesiones para obtener resultados favorables varió entre 8 y 10 aplicaciones. Dentro de los efectos adversos más importantes resalta la hiperpigmentación postinflamatoria y la eliminación del estrato superficial de la piel post láser. Todos fueron controlados sin dejar lesiones residuales permanentes. Conclusión: El láser Q-switched Alexandrita de 755 nm es una tecnología efectiva para lograr un alto grado de despigmentación en el tratamiento del nevus de Ota y puede ser considerado como un tratamiento de primera línea para el manejo de esta patología.
Introduction: Ota nevus is a benign dermal melanocytic hamartoma with a macular appearance, poorly defined and in a gray-black patch that generally affects the first and second branches of the trigeminal unilaterally. Objective: To evaluate the efficacy, safety and adverse events caused by the application of 755 nm Alexandrite laser for the treatment of Ota nevus. Methods: Case series of 10 phototype IV patients with unilateral Ota Nevus treated between January 2017 and December 2018, which were treated with this light energy and with defined parameters. Results: The mean age was 29 years. The patients who completed the treatment did not show repigmentation in the treated lesion and the satisfaction index was acceptable. It was observed that the average of sessions to obtain favorable results varied between 8 and 10 applications. Among the most important adverse effects, post-inflammatory hyperpigmentation and the removal of the superficial layer of the post laser skin stand out. All were controlled without leaving permanent residual lesions. Conclusion: The 755 nm Alexandrite Q-switched laser is an effective technology to achieve a high degree of depigmentation in the treatment of Ota nevus and can be considered as a first-line treatment for the management of this pathology.
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Objective To evaluate the clinical effects and safety of Er:YAG fractional laser for facial rejuvenation.Methods Altogether 559 patients aged from 32 to 58 years old with obvious pigmentary lesions and wrinkles in the face were given 2 courses of restoration treatment with the Pixel Er:YAG fractional laser.The patients paid a return visit a month later after the last treatment.With the results of clinical observation and photograph-based comparison,the therapeutic effects were graded by disappearance of pigmentary lesions and elimination of facial wrinkles.Complications such as hyperpigmentation,depigmentation and hyperplastic scar were observed.Results Among the 559 patients, there were 103 cases (18.4%) of slight effect, 378 cases (67.6%) of moderate effect, and 78 cases (14%) of excellent effect,with the total effective rate of 100% and a satisfactory rate of 81.6%.The was no complication such as hyperpigmentation,depigmentation and hyperplastic scar occurred.Effective maintaining rate within 6 months was 67%.Conclusion Er:YAG fractional laser is safe and effective for facial rejuvenation and worthy of promotion.
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BACKGROUND: Chemical peels using glycolic acid and tretinoin are known to be safe and effective for treating facial pigmentary lesions. OBJECTIVE: We evaluated and compared the efficacy of tretinoin and glycolic acid peeling for facial pigmentary lesions by using a digital camera and L*a*b* color scale in Adobe Photoshop 5.5(R) METHODS: Thirty eight patients with facial pigmentary lesions were treated with 50% glycolic acid and 1% tretinoin peelings. The treatment was performed 2-3 times per week for a period of 2 weeks and a half. Exposure time was 2 minutes for the glycolic acid and 6 hours for the tretinoin. Before and after the treatment, pigmentary lesions were evaluated using self evaluation forms and the L*a*b* color system (Commission International de I'Eclairage) in Adobe Photoshop 5.5(r) (Adobe Systems Incorporated, USA). Corneometer (Corneometer(r) CM820, Courage Khazaka Electronic GmbH, Germany) was used for the evaluation of skin hydration before and after the treatment. RESULTS: Facial pigmentary lesions were significantly improved in 10 out of 38 patients after 50% glycolic acid peeling and in 12 out of 38 patients after 1% tretinoin peeling. The state of hydration of the treated skin improved significantly after the peeling using both 50% glycolic acid and 1% tretinoin. CONCLUSION: Topical 1% tretinoin peeling is as effective as 50% glycolic acid peeling in the treatment of facial pigmentary lesions and more frequent peeling results in quicker improvement than the previous studies without significant side effects.