Lipossarcoma primário ósseo da coluna lombar: relato de caso / Primary liposarcoma of the lumbar spine: case report

Relatamos um caso raro de lipossarcoma primário ósseo da coluna lombar, do qual encontramos apenas um relato semelhante na literatura. Paciente do sexo feminino, 60 anos de idade, com clínica de lombociatalgia à esquerda há aproximadamente seis meses. Nos exames de imagem foi encontrado um tumor destrutivo do corpo vertebral de L4 e a ressonância nuclear magnética (RNM) revelou uma lesão tumoral com hipossinal em T1 e hipersinal em T2. O diagnóstico histológico foi difícil e a imuno-histoquímica confirmou o diagnóstico. O tratamento cirúrgico foi realizado com ressecção ampla, descompressão da medula espinhal, fusão anterior e posterior de L3 a L5, complementada pela radioterapia e quimioterapia. Após três anos, uma tomografia computadorizada (TC) evidenciou lesão expansiva no pulmão. Apesar de sua raridade, o lipossarcoma deve ser considerado no diagnóstico diferencial de ciatalgia e dos tumores primários da coluna vertebral.

We report a rare case of primary bone liposarcoma of the lumbar spine, for which only one case has been reported. A female patient, 60 years of age, with lumbar pain and left sciatalgy for six months. In the imaging exams, a destructive tumor was found in the L4 vertebral body, and magnetic resonance imaging (MRI) revealed a tumoral lesion with T1 hiposignal and T2 hypersignal. Histological diagnosis was difficult, and immunohistochemistry confirmed the diagnosis. Surgical treatment was performed with wide ressection, spinal cord decompression, and anterior and posterior fusion of L3 to L5 complemented by radiotherapy and chemotherapy. After three years, a computed tomography (CT) scan evidenced an expansive injury in the lung. Despite its rarity, liposarcoma should be considered in the differential diagnosis of sciatica and primary tumors of the spine.

Primary Round Cell Liposarcoma of the Omentum: A case report

Liposarcoma is one of the most common soft tissue sarcomas in adults and its incidence rate is above 10% of all soft tissue sarcoma. The two common sites of liposarcoma are the extremities, particularly the thigh, and the retroperitoneum, but it developes rarely in spermatic cord, testis, chest wall and breast, mediastinum, omentum and mesentery. Primary solid tumors of omentum are exceedingly rare. Most of them are of mesenchymal origin and about one-half of them are malignant. Primary liposarcoma occurring in the omentum has been reported rarely, and especially round cell type liposarcoma, one of the histologic subtype of liposarcoma, has been known to be extremely rare. Recently, we experienced a patient with round cell liposarcoma arising primarily in the omentum. Herein, we report the clinical case with a consideration of the cytopathologic and ultrastructural features and a review of the literature.