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Korean Journal of Medicine ; : 457-460, 2015.
Artigo em Coreano | WPRIM | ID: wpr-153842

RESUMO

Despite the increasing use of alternative analgesic agents, salicylate overdose remains a not-uncommon problem. Severe poisoning is life threatening, so prompt treatment and supportive measures are required to reduce mortality. Generally, salicylate intoxication results in the development of high-anion-gap metabolic acidosis. However, outside of Korea, normal-anion-gap or negative-anion-gap metabolic acidosis with hyperchloremia is rarely reported. We report herein the case of an 83-year-old female patient with chronic aspirin intake who presented with hyperchloremia and a negative anion gap. The patient's symptoms improved with conservative treatment and hemodialysis; notably, her chloride levels decreased as her blood salicylate concentrations decreased. Salicylate may cause hyperchloremia, demonstrating the importance of careful documentation of patient medication histories.


Assuntos
Idoso de 80 Anos ou mais , Feminino , Humanos , Equilíbrio Ácido-Base , Acidose , Analgésicos , Aspirina , Coreia (Geográfico) , Mortalidade , Intoxicação , Diálise Renal
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