RESUMO
Objective To evaluate the life quality among the rural elderly residents with cardiovascular diseases and to explore the influencing factors in order to provide evidences for developing prevention measures.Methods A random sampling technique was employed,a total of 620 residents with hypertension and coronary heart disease (CHD)aged over 60 years in Jinhua City was selected.And an investigation including questionnaire and life quality SF -36 scale was conducted.The influencing factors were analyzed by multiple linear regression.Results The average score of life quality among the rural residents with cardiovascular diseases was 69.10 ±17.86.Scores of all dimensions were significantly lower in the elderly (>=70 years)than that among the <70 years (P <0.05).There was significant difference on the scores in seven dimensions (PF,RP,BP,GH,VT,SF,RE)(P <0.05).Scores of patients with annual income of 5 000 yuan were significantly lower than those with annual income of 5 000 -20 000 yuan,while scores decreased when above 20 000 yuan.Smoking,alcohol and tea were the influencing factors of scores in each dimension (P < 0.05 ).Multiple linear regression analysis showed that age,family income,smoking and drinking were the risk factors of life quality (P <0.01). Conclusion The life quality of the elderly with cardiovascular diseases in rural areas is almost on a normal level,but scores of general health and mental health is lower.It's urgent to strengthen the chronic disease management in order to improve the life quality of rural elderly residents with chronic diseases.
RESUMO
Perioperative Management is not a new issue in clinical practice,but a nonnegligible core issue related to the safety of surgical patients.In recent years,it has been neglected by surgeons.We must pay great attention and vigilance to perioperative management for the quality and safety of surgical practice.A master surgeon is from the patients' bedside-Mutual Encouragement !
RESUMO
Objective To evaluate the quality of four domestic and three imported fourth-generation HIV diagnostic reagents.Methods The specificity and sensitivity of these assays were analyzed when testing HIV negative samples and HIV-1 RNA positive samples.The relative seroconversion sensitivity index was analyzed when testing BBI seroconversion panels.Results The sensitivity of seven 4th-generation assays were 100％ (95％ CI:99.86％-100％ ),and one sample at the window period of HIV-1 infection were detected as positive.Of the seven assays,one imported assay exhibited the relative largeδ + value (1.0892),and the small δ+ value were found on the remaining six assays (0.0836-0.3003 ).For the samples negative for HIV antibody,varying degrees of false positives were observed on the seven assays ( specificity:97.80％ -99.60％,δ- value:-1.3803 to -0.4778).When testing the BBI seroconversion panels,the relative seroconversion sensitivity index of domestic assays were -0.500-0,however,which of imported assays were -0.600 and -0.700.Conclusion The seven reagents exhibited high sensitivity and specificity.The 4th generation HIV assays can be used as blood screening reagents to find the samples at window period of HIV-1 infection,thus indicating the certain meaning in reducing the transmission risk of HIV-1 for fourth-generation HIV diagnostic reagents.However,the better efficiency to detect HIV-1 early infection was observed on the imported assays than on the domestic assays.
RESUMO
Objective To establish the quality standard for Guishao Zhenxian Tablets. Methods Radix Glycyrrhizae,Radix Codonopsis,Radix Bupleuri were identified by TLC. The content of paeoniflorin in the preparation was determined by HPLC. Results The spots of TLC color spectrum were distinct and there was nointerference from the negative control. The calibration curve was linear over the concentration range of 0.245 2～0.735 6 ?g for paeoniflorin (r=0.999 7) and the average recovery was 98.3%,RSD=1.52% (n=5). Conclusion The established quality standard is convenient and reliable,and can be used to control the quality of Guishao Zhenxian Tablets more effectively.
RESUMO
OBJECTIVE:To prepare compound sparfloxacin auristillae and to establish its quality control method.METHODS:The auristillae was prepared with glycerin and alcohol as solvents;the contents of econazole and sparfloxacin were determined by UV spectrophotometry with their respective detection wavelengths at360nm and297nm respectively,and the stability of which were determined as well.RESULTS:The linear concentration ranges of econazole and sparfloxacin were2～400?g/ml and0.4～80?g/ml respectively;the average recovery of econazole and sparfloxacin were100.96%(RSD=0.99%)and100.38%(RSD=0.44%)respectively.The expiry date(shelf life)of the finished products was above2years.CON?CLUSION:The preparation is simple in preparation,good in stability;and the quality control method is simple and easy,rapid,accurate and feasible.