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1.
Chinese Journal of Primary Medicine and Pharmacy ; (12): 1174-1177, 2018.
Artigo em Chinês | WPRIM | ID: wpr-807429

RESUMO

Objective@#To investigate the effect of atorvastatin combined with Quick Heart-Reliever Pill on blood fat and serum inflammatory factors of elderly patients with coronary artery disease.@*Methods@#184 elderly patients with coronary artery disease were selected, and they were randomly divided into control group and observation group according to the digital table, 92 cases in each group.The control group was given atorvastatin treatment, while the observation group was given atorvastatin combined with Quick Heart-Reliever Pill.The levels of serum inflammatory factors(TNF-α, CRP, MMP-9 and IL-6) and blood lipid(TC, TG, HDL-C, LDL-C) in the two groups after 1 month treatment were compared.@*Results@#After 1 month treatment, the blood lipid levels(TC, TG, HDL-C, LDL-C) of the observation group were significantly lower than those of the control group[(4.26±0.68)mmoL/L vs.(5.14±0.61)mmoL/L, (1.51±0.17)mmoL/L vs.(1.75±0.19)mmoL/L, (1.60±0.38)mmoL/L vs.(1.52±0.43)mmoL/L, (3.01±0.32)mmoL/L vs.(3.18±0.42)mmoL/L, t=2.774, 2.355, 1.976, 2.476, all P<0.05], and the levels of serum inflammatory factors(TNF-α, CRP, MMP-9 and IL-6) of the observation group were significantly lower than those of the control group[(50.35±7.47)ng/L vs.(64.83±8.96)ng/L, (46.50±5.93)mg/L vs.(57.77±6.48)mg/L, (35.44±6.17)μg/L vs.(46.85±7.44)μg/L, (16.84±6.72)ng/L vs.(26.85±9.42)ng/L, t=11.905, 12.306, 22.159, 8.297, all P<0.05].@*Conclusion@#Atorvastatin combined with Quick Heart-Reliever Pill in the treatment of elderly patients with coronary heart disease can achieve notable effects without increasing the liver burden, which can also effectively refine the blood lipid in patients, reduce the inflammatory factors levels, and it is worthy of clinical promotion.

2.
Chinese Journal of Biochemical Pharmaceutics ; (6): 193-194, 2017.
Artigo em Chinês | WPRIM | ID: wpr-659742

RESUMO

Objective To compare the clinical effect of quick acting Kyushin pills and compound Danshen dripping pills in the treatment of coronary heart disease angina pectoris. Methods 98 patients with angina pectoris from December 2015 to April 2017 were randomly divided into group A (n=49) and group B (n=49) by random number table. A group on the basis of conventional therapy plus compound Danshen Pill, B group in the conventional treatment based on the use of available Kyushin Pills, recorded the treatment of two groups of patients with angina pectoris of coronary heart disease before and after 2 weeks of treatment, angina frequency (weekly), duration (weekly) changes. Results Two groups of patients with angina pectoris were successfully completed treatment, there was no significant difference in the frequency and duration of angina pectoris before treatment. After the two groups after 2 weeks of treatment duration, seizure frequency were significantly reduced than before (P<0.05), the above indexes in group B decreased than group A (P<0.05). Conclusion The use of conventional therapy based on the use of Kyushin Pills can significantly relieve angina pectoris in patients with coronary heart disease, and has positive significance for the protection of its efficacy and prognosis.

3.
Chinese Journal of Biochemical Pharmaceutics ; (6): 193-194, 2017.
Artigo em Chinês | WPRIM | ID: wpr-657544

RESUMO

Objective To compare the clinical effect of quick acting Kyushin pills and compound Danshen dripping pills in the treatment of coronary heart disease angina pectoris. Methods 98 patients with angina pectoris from December 2015 to April 2017 were randomly divided into group A (n=49) and group B (n=49) by random number table. A group on the basis of conventional therapy plus compound Danshen Pill, B group in the conventional treatment based on the use of available Kyushin Pills, recorded the treatment of two groups of patients with angina pectoris of coronary heart disease before and after 2 weeks of treatment, angina frequency (weekly), duration (weekly) changes. Results Two groups of patients with angina pectoris were successfully completed treatment, there was no significant difference in the frequency and duration of angina pectoris before treatment. After the two groups after 2 weeks of treatment duration, seizure frequency were significantly reduced than before (P<0.05), the above indexes in group B decreased than group A (P<0.05). Conclusion The use of conventional therapy based on the use of Kyushin Pills can significantly relieve angina pectoris in patients with coronary heart disease, and has positive significance for the protection of its efficacy and prognosis.

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