Current Sedation Practices in Procedures under Spinal Anaesthesia (SA)

Introduction: Peri-operative anxiety and stress associated with procedures under Spinal anaesthesia (SA) is common and sedation may help improving compliance of the patient and quality of SA. There is no standard sedation protocol for SA. Study aimed to observe the various sedation protocols practiced in our institute during SA with regard to drugs used and their dosages, sedation levels, effect on the duration of SA and to assess the patient satisfaction level. Material and methods:This was a prospective observational study comprised of patients undergoing elective surgeries under SA. IV sedation was given as per the attending anaesthesiologist’s discretion after SA. We noted hemodynamic parameters, RSS, two-dermatomal regression time, Patient satisfaction scores etc. Epi Info 7.2 software was used for statistical analysis. Results Total 500 patients received Dexmedetomidine (189), Midazolam (301) and Propofol (10) as IV sedation. Mean time required for regression of two-dermatomal sensory levels and for rescue analgesia requirement was prolonged in Dexmedetomidine (121.64, 203.75 mins resp.), as compared to Midazolam and Propofol. Mean Ramsay Sedation Score (2.4- 3) and Patient satisfaction scores (6-7.5) were comparable in all the drugs. Hemodynamic parameters were stable and comparable. No hypotension, respiratory depression seen except bradycardia (HR<50) noted in 4 patients of Dexmedetomidine. Conclusion: Drugs used for sedation in 500 patients were Dexmedetomidine, Midazolam and Propofol. All the drugs provided optimum sedation without respiratory depression with stable hemodynamics and good patient satisfaction. In addition, Dexmedetomidine increased durations of sensory anaesthesia and post-operative analgesia

Detection of enteric viruses in pancreas and spleen of broilers with runting-stunting syndrome (RSS) / Detecção de vírus entéricos em pâncreas e baço de frangos com a síndrome de nanismo e raquitismo (RSS)

Enteric disease is a multifactorial problem in chickens, which causes gastrointestinal alterations, elevated feed conversions and impairment. In the last years, several enteric viruses were implicated in enteric disease; case reports have shown their presence alone or in concomitant infections during outbreaks and have suggested that they might be determining factors in the aetiology of enteric disease. This study shows high detection rates of enteric viruses in the pancreas and spleen in samples from an outbreak of enteritis and malabsorption in 16 chicken flocks (n=80 broilers). Avian nephritis virus (ANV) was the most ubiquitous virus, present in 75% of the flocks followed by avian rotavirus group A (ART-A) with 68.75%, and by chicken astrovirus (CAstV) and chicken parvovirus (ChPV) in 43.75% of samples. Viruses were present in the pancreas of positive flocks at extremely high rates: 100% for ART-A, 91.7% for ANV, 100% for CAstV and 57.14% for ChPV. By contrast, only 16.7% and 57.14% of intestine samples were positive for ANV and CAstV, respectively. Avian reovirus (AReo) and avian adenovirus group 1 (FAdV-1) were not detected. These results suggest that high viral detection rates in pancreas samples may be a result of viremia during enteric disease, with subsequent damage of the exocrine pancreas, leading to runting-stunting syndrome (RSS).(AU)

A doença entérica é um problema multifatorial em galinhas que causa alterações gastrointestinais, conversão alimentar elevada e deficiência de crescimento. Nos últimos anos, os vírus entéricos foram associados à doença entérica; casos reportados mostraram a infecção de um único vírus e também infecções concomitantes durante os surtos sugerindo a presença de múltiplos fatores etiológicos nas doenças entéricas. Este estudo mostra uma alta taxa de detecção dos vírus entéricos em amostras de pâncreas e baço de um surto de enterite e má-absorção em 16 lotes de frangos (n=80 frangos). O vírus de nefrite aviária (ANV) foi o vírus mais detectado, estando presente em 75% dos lotes seguido pelo rotavírus aviário grupo A (ART-A) em 68,75% dos casos, e pelo astrovirus (CAstV) e parvovírus aviários (ChPV), ambos em 43,75% das amostras. Os vírus estavam presentes no pâncreas dos lotes positivos em percentuais elevados: 100% para ART-A e CAstV; 91,7% para ANV, e em 57,14% para ChPV. Em contraste, somente 16,7% e 57,14%, em amostras de intestino, foram positivos para ANV e CAstV, respectivamente. Reovírus aviário (AReo) e o adenovírus do grupo 1 (FAdV-1) não foram detectados. Estes resultados sugerem que os elevados percentuais de vírus detectados em amostras de pâncreas podem estar associados à viremia durante a doença entérica, com subsequente lesão no pâncreas exócrino das aves levando ao desenvolvimento da síndrome de nanismo e raquitismo.(AU)

Avaliação dos resíduos de serviços de saúde do Grupo A em hospitais de Vitória (ES), Brasil / Evaluation of healthcare wastes service of group A in the hospitals of Vitória (ES), Brazil

Nesta pesquisa, quantificam-se e classificam-se, conforme a Resolução RDC ANVISA nº 306/2004, os Resíduos de Serviço de Saúde do Grupo A, gerados em seis hospitais de Vitória (ES), Brasil. Os resíduos acondicionados sem segregação foram separados por grupos e subgrupos, resultando em: 57% do Grupo D - comum; 41% do Grupo A - risco biológico; 1,5% do Grupo B - risco químico e 0,05% do Grupo E - perfuro-cortantes. O peso específico aparente foi de 106,2 kg.m-3 e a taxa média de geração de resíduos foi 2,68 kg.(leito.ocupado.dia)-1. Ao se segregar os resíduos do Grupo D, a taxa de geração do Grupo A passou a ser 1,15 kg.(leito.ocupado.dia)-1, resultando em 58% de redução nos custos com incineração. Com a segregação dos Grupos B, D, E e do subgrupo A4, a taxa de geração passou a ser 0,18 kg.(leito.ocupado.dia)-1, com uma redução nos custos com incineração de 93%.

In this research the Health Care Waste of Group A (Resíduos de Serviço de Saúde - RSS), collected from six hospitals in Vitoria (ES), Brazil, was quantified and classified according with ANVISA's Resolution RDC nº 306/2004. The waste was packaged without segregation and afterwards separated by groups and subgroups, with the following results/percentages: 57% Group D - common; 41% Group A - biological risk; 1.5% Group B - chemical risk; and 0.05% Group E - sharps. The apparent bulk density was 106.2 kg/m3. The average production rate of this mixture was 2.68 kg per occupied bed daily. By separating the mixture of the RSS from group D, the average production rate of Group A changed to 1.15 kg per occupied bed daily, reducing incineration costs by 58%. By segregating Groups B, D, E and subgroup A4, the average production rate changed to 0.18 kg per occupied bed per day with a reduction of 93% in incineration costs.

Popularizing subscription of personal RSS products in subject librarians / 中华医学图书情报杂志

After the problems found in academic information push service and information literacy training of sub-ject librarians in Medical Library of Chinese PLA were analyzed , the concrete contents of subscribing personal RSS products in a certain institute of Academy of Military Medical Sciences and the feedback of its users were described with suggestions put forward for deepening the academic information push service, such as establishing personal RSS account for research rooms and implanting certain RSS subscription contents into the subject service platform.

New way for medical graduate students to collect and manage academic literature in the web 2.0 era / 中华医学科研管理杂志

Most academic information appears in the database and academic websites;in rencent years the blog and podcast also transmit academic information.Medical graduates need to check new information regularly after busy routine work,but how to effectively collect and manage academic information is a problem.This paper describes the new strategies and methods for them to use.

Customized Information Service and Retrieval of Biomedicine / 中华医学教育探索杂志

This article introduces the customized information service,including its emergence,characteristic,contents as well as the way by which it is achieved.And then the process is explained by giving the demonstration of RSS customized information service provided by PubMed system.

Analysis of total flavone in Shuxuening Tablet by resonance scattering spectrum / 中草药

Object To develop a resonance scattering spectral(RSS) method for the determination of total flavone in Shuxuening Tablet, and study the cause of RSS enhancement. Methods The BSA Mo (Ⅵ) qucercetin (Qu) system was investigated by RSS method. Results There were two resonance sacttering peaks at 470 and 525 nm. The Qu concentration in the range of 0-2 4 mg/L is linear to the resonance scattering intensity I 470 nm , with a detection limit of 0 3 mg/L. Conclusion This method is simple, sensitive and suitable for the determination of total flavone in Shuxuening Tablet. The spectral results demonstrate that the formation of [BSA Mo Qu] n associated particle and the interface between the particle solid phase and water phase results to its enhanced RSS.