Effect on ingredients in Naru Sanwei Pill on Radix aconiti kusnezofii by ESI-MS~n / 中成药

AIM:To study the bioactive components effect of every kind of herbal in Naru Sanwei Pill (Fructus litseae, Fructus chebulae) on Radix Aconiti kusnezoffii. METHODS: Analysising the Naru Sanwei Pill, adding the extraction of Radix Aconiti kusnezoffii to Fructus chebulae and Fructus litseae and was analyzed by ESI-MS~n. RESULTS: The quantity of mesaconitin was low in the extraction of Aconitum kusnezoffii Reichb,and Fructus chebulae.Long Pepper did not have much effect on alkaloids of Aconiti kusnezoffii Reichb. CONCLUSION: Fructus chebulae reduced toxicity in the process of Radix aconiti kusnezoffii,through lowering the dissolving-out of aconitine.