Bibliometric Analysis of Research on Boesenbergia rotunda, Pinostrobin, and Their Derivatives: Dominance of Southeast Asian Researchers

Pinostrobin, marker compounds from Boesenbergia rotunda with various pharmacological activities, have been studied extensively, including synthesizing its derivatives, which have potent pharmacological activities. This study aims to describe research related to B. rotunda, pinostrobin, and their derivatives. Metadata information was collected from Scopus in August 2022, with three keywords searched for article titles, abstracts, and keywords. Analysis and research mapping were carried out with VOSviewer. The most widely used synonym for the plant name was "Boesenbergia rotunda", in which Norzulaani Khalid from the University of Malaya, Malaysia, mostly reported research with the keywords "Boesenbergia rotunda", "pinostrobin", and "derivative". The majority of researchers come from institutions in Southeast Asia, such as Malaysia, Thailand, and Indonesia. Interestingly, no Chinese researchers have reported studies on this topic. The journals and publishers that publish the most articles with these three keywords are Bioorganic and Medicinal Chemistry Letters and Elsevier, respectively. This information will make it easier for researchers on this topic to find partners for collaboration and determine journals to publish their research results.

La pinostrobina, compuesto de marcadores de Boesenbergia rotunda con diversas actividades farmacológicas, se ha estudiado ampliamente, incluida la síntesis de sus derivados que tienen potentes actividades farmacológicas. Este estudio tuvo como objetivo describir investigaciones relacionadas con B. rotunda, pinostrobina y sus derivados. La información de metadatos se recopiló de Scopus en agosto de 2022, con tres palabras clave buscadas para títulos de artículos, resúmenes y palabras clave. El análisis y el mapeo de la investigación se realizaron con VOSviewer. El sinónimo más utilizado para el nombre de la planta fue "Boesenbergia rotunda", en el que Norzulaani Khalid de la Universidad de Malaya, Malasia, informó principalmente sobre investigaciones con las palabras clave "Boesenbergia rotunda", "pinostrobina" y "derivado". La mayoría de los investigadores provienen de instituciones del sudeste asiático como Malasia, Tailandia e Indonesia. Curiosamente, ningún investigador chino ha informado de estudios sobre este tema. Las revistas y editoriales que más artículos publican con estas tres palabras clave son Bioorganic and Medicinal Chemistry Letters y Elsevier. Esta información facilitará a los investigadores sobre este tema encontrar colaboraciones y determinar las revistas para publicar los resultados de sus investigaciones.

Reflections on manufacturer′s reference materials of preventive human vaccines / 中国生物制品学杂志

@#Reference materials for vaccine are the standard rulers for quality control,dose determination and effectiveness evaluation of vaccines. Manufacturer's reference materials are a kind of the working standards that are directly used by vaccine enterprises in the process of production,quality control and evaluation,of which the accuracy and stability play a key role in ensuring the consistency between batches,safety and effectiveness of vaccines. Based on the investigation into the current management situation of manufacturer's reference materials in domestic representative vaccine enterprises,and combined with the relevant guidelines and regulations such as World Health Organization guidelines and Chinese Pharmacopoeia,this paper put forward the key points that should be considered in the establishment and application of manufacturer's reference materials of preventive human vaccines. It is also suggested to formulate the guidelines about manufacturer's reference materials in order to regulate the development and application of working reference materials.

Gestores de referencias bibliográficas y su impacto en las investigaciones / Bibliographic reference managers and their impact on research

Resumen La incorporación de los gestores de referencias bibliográficas a las investigaciones se debe a sus beneficios como organizador de citas, referencias y como un recurso informático para el desarrollo de proyectos. El objetivo de este artículo es actualizar conocimientos en los últimos 5 años, sobre el uso e implicación de los Gestores de Referencias en las investigaciones. Se realizó una revisión documental que permitió consultar 133 fuentes de información asociadas a cinco grupos de documentos: I. Rol que desempeñan los gestores de referencias bibliográficas en el desarrollo de habilidades informacionales y competencias investigativas. II. Uso de los gestores como herramientas en la investigación. III. Los gestores en temas de materiales didácticos. IV. En la confección de citas y referencias y V. Para otros objetivos de investigación. Se utilizaron el Zotero, el Excel 2013 y el paquete estadístico SPSS. Se calcularon frecuencias absolutas y porcentajes, así como la Moda para los grupos conformados. Entre otras conclusiones importantes, al analizar el comportamiento de la producción científica, la Moda señala al grupo II Uso de los gestores como herramientas en la investigación, como el más frecuente dentro de los documentos estudiados, por lo que se recomienda su estudio y actualización permanente.

Abstract The incorporation of bibliographic reference managers in research is due to its benefits as an organizer of citations, references and as an informatics resource for the development of projects. The objective of this article is to update knowledge in the last 5 years on the use and implication of reference managers in research. A documentary review was carried out which allowed to consult 133 sources of information associated with five groups of documents: I. Role of bibliographic reference managers in the development of informational skills and research competencies. II. Use of managers as tools in research. III. Managers in didactic materials issues. IV. In the preparation of citations and references and V. For other research objectives. Zotero, Excel 2013 and the SPSS statistical package were used. Absolute frequencies and percentages were calculated, as well as the mode for the groups formed. Among other important conclusions, when analyzing the behavior of scientific production, Moda points out group II Use of managers as tools in research, as the most frequent within the documents studied, so its study and permanent updating is recommended.

Referencias de índice de masa corporal. Precisión diagnóstica con área grasa braquial en escolares argentinos / Body mass index references. Diagnostic accuracy with the upper-arm fat area in Argentine schoolchildren

El índice de masa corporal (IMC) es una eficaz herramienta para detectar la sobrecarga ponderal en niños y adolescentes, asociado a la adiposidad corporal. Objetivo. Analizar la concordancia, sensibilidad y especificidad de tres referencias internacionales de IMC/edad (OMS, IOTF y CDC) para diagnosticar el exceso ponderal y conocer su precisión diagnóstica para identificar el exceso de adiposidad con relación al área grasa braquial (AGB) en población infanto juvenil de Argentina. Materiales y métodos. Se realizó un estudio multicéntrico, descriptivo-comparativo y transversal entre 2003 y 2008, en 22.658 niños y adolescentes argentinos de 4 a 13 años de edad. A partir del peso, talla, circunferencia del brazo y pliegue tricipital, se calcularon IMC y AGB. Se analizó la concordancia, sensibilidad y especificidad de referencias de IMC/edad (OMS, CDC, IOTF) y la precisión diagnóstica (curvas ROC) para identificar exceso de adiposidad, a partir del AGB, así como el punto de corte óptimo (PCO). Resultados. Las tres referencias tuvieron buena concordancia. La mayor sensibilidad correspondió a OMS y la mayor especificidad a IOTF. El área bajo la curva (ABC) fue mayor en Z-IMC/IOTF en varones y en Z-IMC/OMS en mujeres. Los PCO mostraron discrepancias, siendo mayores con OMS. Conclusión. Las tres referencias muestran similar precisión diagnóstica para detectar alta reserva calórica, con puntos de corte óptimo para las puntuaciones Z-IMC menores a 2 Z scores. Esto resulta relevante para la identificación de exceso de adiposidad en poblaciones, en relación con la implementación de políticas públicas de prevención de enfermedades crónicas no transmisibles(AU)

The body mass index (BMI) is an effective tool to detect weight overload in children and adolescents, associated with body adiposity. Objective. To analyze the concordance, sensitivity and specificity of three international BMI/age references (WHO, IOTF and CDC) to diagnose excess weight and to know their diagnostic accuracy to identify excess adiposity in relation to the brachial fat area (BFA) in Argentine child-youth population. Materials and methods. A multicenter, descriptive- comparative and cross-sectional study was carried out between 2003 and 2008 in 22.658 Argentine children and adolescents between aged 4 to 13 years. From the weight, height, arm circumference and tricipital fold, BMI and BFA were calculated. The concordance, sensitivity, and specificity of BMI / age references (WHO, IOTF, CDC,) were analyzed and the diagnostic precision (ROC curves) to identify excess adiposity, from the BFA, as well as the optimal cut-off point (OCP). Results. The three references had good agreement, the highest sensitivity corresponded to WHO and the highest specificity to IOTF. The area under the curve (AUC) was greater in Z-BMI/IOTF in men and in Z-BMI/WHO in women. The OCPs showed discrepancies, being higher with WHO. Conclusion. The three references show similar diagnostic accuracy to detect high caloric reserve, but with cut-off points for Z-BMI scores less than 2 Z scores. This is relevant for the identification of excess adiposity in populations in relation to the implementation of public policies for the prevention of chronic non-communicable diseases(AU)

A study of referral pattern to pediatric ophthalmology department in a tertiary eye-care center of South-India

Purpose: The study was aimed at finding out the present pattern of referrals to the Pediatric Ophthalmology outpatient department (OPD) in a tertiary eye care hospital and thus identify the discrepancy of referral, if any, which would help to modify and enhance the practice guidelines. Methods: The study was conducted by retrospectively collecting data from all referral letters that were already uploaded in the Electronic Medical Report (EMR) against all patients from June 2019 to December 2019. All pediatric patients in the age group of 0–16 years were included in the study. The practicing field of referring clinicians was noted along with the maximum information that could be collected from the referral letter and were thus assessed for the quality, accuracy, and timely referral. Results: Out of 77 referrals received in the study period, six referral letters neither had any mention of the designation of the referring clinician nor any specific diagnosis or details. Thus, only 71 patients were included for further study. The referring clinicians were mainly ophthalmologists, pediatricians, general practitioners (GPs), and others (cardiologists, neurologists). Maximum patients were referred by ophthalmologists (76%) but visual acuity was noted only for 30% of these patients. Almost half of the referral diagnosis was accurate. Pediatrician referrals were found to be more detailed and précised. Conclusion: There is a need for a standardized hospital?specific format of referrals and basic training to primary care providers on some simple tests (Lights reflex tests) for identifying the “red flags” in pediatric eye examination and thus enhancing the quality and timely referral per se

Anatomic and functional analysis of thoracic kyphosis and lumbar lordosis / Avaliação anatômica e funcional da cifose torácica e lordose lombar / Análisis anatómica y funcionalde la cifosis torácica y la lordosis lumbar

ABSTRACT Objective: Rate and compare radiographic measurements of thoracic kyphosis and lumbar lordosis using anatomical and dynamic parameters. Methods: Measurements were performed on lateral radiographs of 10 adults of both sexes without spinal disease or deformity. Thoracic kyphosis and lumbar lordosis were measured using anatomical parameters (T1-T12, T4-T12, T5-T12 and L1-S1) or dynamic parameters (cervicothoracic or thoracolumbar inflection point). Results: Thoracic kyphosis and lumbar lordosis were different in 30% of subjects. Differences in thoracic kyphosis values were observed according to the anatomical reference used for measurement. Lumbar lordosis wasn`t statistical difference considering the anatomical or dynamic reference, but in 30% of the individuals the inflection point was different from the anatomical reference. Conclusions: Thoracic kyphosis and lumbar lordosis values differ according to anatomical and dynamic references. The reference used must be considered in the measurement and interpretation of values. Level of evidence IV; Case series.

RESUMO: Objetivo: Avaliar e comparar as mensurações radiográficas da cifose torácica e lordose lombar utilizando parâmetros anatômicos e dinâmicos. Métodos: As mensurações foram realizadas nas radiografias em perfil de 10 adultos de ambos os sexos sem doença ou deformidade da coluna vertebral. A cifose torácica e a lordose lombar foram mensuradas utilizando parâmetros anatômicos (T1-T12,T4-T12, T5-T12 e L1-S1) ou dinâmicos (ponto de inflexão cervicotorácico ou toracolombar) Resultados: As referências anatômicas e dinâmicas para a identificação da cifose torácica e lordose lombar foram diferentes em 30% dos indivíduos. Foi observado diferença dos valores da cifose torácica de acordo com a referência anatômica utilizada para a mensuração. A lordose lombar não apresentou diferença estatística considerando a referência anatômica ou dinâmica, mas em 30% dos indivíduos o ponto de inflexão era diferente da referência anatômica. Conclusões: Os valores da cifose torácica e lordose lombar apresentam diferenças de acordo com as referências anatômicas e dinâmicas. A referência utilizada deve ser considerada na mensuração e interpretação dos valores. Nível de evidência IV; Série de casos.

RESUMEN: Objetivo: Calificar y comparar medidas radiográficas de cifosis torácica y lordosis lumbar utilizando parámetros anatómicos y dinámicos. Métodos: Las mediciones se realizaron en radiografías laterales de 10 adultos de ambos sexos sin enfermedad o deformidad de la columna. La cifosis torácica y la lordosis lumbar se midieron mediante parámetros anatómicos (T1-T12, T4-T12, T5-T12 y L1-S1) o dinámicos (punto de inflexión cervicotorácico o toracolumbar). Resultados: La cifosis torácica y la lordosis lumbar fueron diferentes en el 30% de los sujetos. Se observaron diferencias en los valores de cifosis torácica según la referencia anatómica utilizada para la medición. La lordosis lumbar no fue diferencia estadística considerando la referencia anatómica o dinámica, pero en el 30% de los individuos el punto de inflexión fue diferente de la referencia anatómica. Conclusiones: Los valores de cifosis torácica y lordosis lumbar difieren según referencias anatómicas y dinámicas. La referencia utilizada debe ser considerada en la medición e interpretación de los valores. Nivel de evidencia IV; Series de casos.

Psicología Escolar: interlocución entre las Referencias Técnicas y publicaciones de prácticas / Psicologia escolar: interlocução entre as referências técnicas e publicações de práticas / School psychology: dialogue between technical references and practice publications

Neste artigo discorremos sobre a interlocução entre as "Referências Técnicas para a Atuação de Psicólogas(os) na Educação Básica", documento publicado pelo Conselho Federal de Psicologia, e as publicações de práticas em Psicologia Escolar, considerando as contribuições da área aos processos educacionais que produzem desenvolvimento humano. Este estudo teve como objetivo realizar uma pesquisa bibliográfica sistemática no período de 2009 a 2019 visando identificar a correspondência entre as publicações de práticas de psicólogas(os) no contexto escolar e as propostas apontadas nas Referências Técnicas. O método aplicado foi de Revisão Bibliográfica Sistemática, utilizando-se dos descritores: Psicologia Escolar, Atuação do Psicólogo Escolar e Prática do Psicólogo Escolar. As bases de dados consultadas foram: SciELO, LILACS e CAPES. Concluímos que há exemplos importantes de práticas realizadas no contexto de ensino e aprendizagem que podem servir de referência para diversas intervenções e que se coadunam com as Referências Técnicas.

Este artículo discurre sobre la interlocución entre las "Referencias Técnicas para la Actuación de Psicólogas(os) en la Educación Básica", documento publicado por el Consejo Federal de Psicología, y las publicaciones sobre prácticas en Psicología Escolar, considerando los aportes de dicho campo a los procesos educativos que promueven desarrollo humano. El estudio tuvo como objetivo realizar una investigación bibliográfica sistemática en el periodo entre 2009 y 2019, para identificar cuáles han sido las prácticas de las(os) psicólogas(os) en el contexto escolar y establecer relación con las Referencias Técnicas. El método aplicado fue de Revisión Bibliográfica Sistemática, utilizándose de los descriptores: Psicología Escolar, Actuación del Psicólogo Escolar y Práctica del Psicólogo Escolar. Las bases de datos consultadas fueron: SciELO, LILACS y CAPES. Se concluye que hay ejemplos importantes de prácticas realizadas en el contexto de enseñanza y aprendizaje que pueden servir como referencia para distintas intervenciones, y que coinciden con las Referencias Técnicas.

In this article we discuss the dialogue between the "Technical References for the Performance of Psychologists in Basic Education", a document published by the Federal Council of Psychology, and the publications of practices in School Psychology, considering the contributions of the scope to the educational processes that produce human development. This study aimed to carry out a systematic literature search between 2009 to 2019 in order to identify what psychologists' practices have been in the school context and to establish a relationship with the Technical References. The method applied was Systematic Bibliographic Review, using the descriptors: School Psychology, School Psychologist's Performance and School Psychologist's Practice. The databases consulted were: SciELO, LILACS and CAPES. We conclude that there are important examples of practices carried out in the context of teaching and learning that can serve as a reference for various interventions and that are consistent with the Technical References.

Normative references of fetal chest circumference in a Nigerian population

A linear relationship between gestational age and fetal thoracic size has been observed, with growth occurring at a regular rate from 16 to 40 weeks.Objective: To determine the fetal chest circumference in normal late second and third-trimester pregnancies in a Nigerian population.Materials and Methods: This was a descriptive cross-sectional study carried out on gravid women with normal singleton pregnancies at 22 ­ 38 weeks gestational age. We recruited 440 eligible gravid women. The fetal gestational age was estimated from the last menstrual period and an early first trimester ultrasound report (< 10 weeks). The fetal chest circumference was measured on an axial view of the fetal chest after ensuring adequate visualisation of the four cardiac chambers, both fetal lungs and ribs. The other fetal biometric parameters were determined using the previously established guidelines. Descriptive statistics, Pearson's correlation, and regression analysis were used as appropriate. Statistical tests were considered significant at P ≤ 0.05.Results: The mean age of the subjects was 29.8 ± 4.6 years (range = 18-45 years). The chest circumference of the fetuses ranged from 16.56 ± 0.29 cm to 30.87 ± 6.88 cm. The fetal chest circumferences increased with advancing gestational age (16.56 ± 0.29 cm at 22 weeks to 30.87 ± 6.88 cm at 37 weeks gestational age). There was strong positive correlation between chest circumference and menstrual gestational age (r=0.85, p=<0.0001), biparietal diameter (r=0.88, p<0.0001), abdominal circumference (r=0.90, p<0.0001) and fetal length (r=0.88, p<0.0001).Conclusion: The fetal chest circumference grew as the pregnancy progressed. There was a positive linear correlation between fetal chest circumference and menstrual gestational age as well as the other fetal biometric parameters.

Aplicación móvil para la organización de las referencias bibliográficas por las normas de Vancouver / Mobile Application for the Organization of Bibliographic References by the Vancouver Standards

Introducción: Frecuentemente se identifican dificultades en la organización de las referencias bibliográficas por las Normas de Vancouver. Objetivo: Desarrollar la aplicación para dispositivos móviles Normas de Vancouver-APK para la organización de las referencias bibliográficas. Método: Se utilizó HTML5, CSS3, JavaScript, Java, Visual Studio Code, Android Studio y adobe Photoshop. Resultados: En este trabajo se muestra el prototipo de aplicación Normas de Vancouver-APK para dispositivos móviles, sus ventajas, la dirección electrónica donde se puede descargar, y el manual de usuario para generar y recuperar las referencias bibliográficas a través del llenado del formulario según el tipo de documento utilizado. Conclusiones: La aplicación contribuye a la organización de las referencias bibliográficas por las Normas de Vancouver de una manera más fácil, limitando la complejidad para el que lo redacta(AU)

Introduction: Difficulties are frequently identified in the organization of bibliographic references by the Vancouver Standards. Objective: To develop the Vancouver Rules-APK application for mobile devices for the organization of bibliographic references. Method: HTML5, CSS3, JavaScript, Java, Visual Studio Code, Android Studio and Adobe Photoshop were used for its construction. Results: This work shows the Vancouver Standards-APK application prototype for mobile devices, its advantages, the electronic address where it can be downloaded, and the user manual to generate and retrieve bibliographic references by filling in the form according to the type of document used. Conclusions: The application contributes to the organization of the bibliographic references by the Vancouver Standards in an easier way for the one who writes it(AU)

Reference values of the body composition of young chilean soccer players / Valores de referencia de la composición corporal de jóvenes futbolistas chilenos / Valores de referência da composição corporal de jovens futebolistas chilenos

ABSTRACT Objective: To analyze whether fat mass (FM) and fat-free mass (FFM) should be evaluated by chronological age and/or biological age and propose curves to classify the body composition of young Chilean soccer players. Methods: A cross-sectional descriptive study was developed. Six hundred and forty-two soccer players between 13.0 and 18.9 years of age were recruited. Body mass, height, trunk-cephalic height, and tricipital and subscapular skinfolds were evaluated. Biological maturation was determined using peak height velocity age (PHV) and the percentage of fat mass was estimated by regression equations. The reference percentiles were calculated using the LMS method. Results: The values of R2 were lower for chronological age (FM = 0.07% and FFM = 0.13%) than for biological age (FM = 0.31% and FFM = 0.50%). Eleven percentiles (p3, p5, p10, p15, p25, p50, p75, p85, p90, p95 and p97) were calculated for FFM and FM. Conclusion: Biological age (PHV) is a better predictor of FFM and FM than chronological age. The references proposed can be used to monitor the body composition of young Chilean soccer players. Level of Evidence II; Diagnostic Study .

Resumen Objetivo: Analizar si la masa grasa (MG) y la masa libre de grasa (MLG) deben ser evaluadas por la edad cronológica y/o por la edad biológica, y proponer curvas para clasificar la composición corporal de jóvenes futbolistas chilenos. Métodos: Se elaboró un estudio descriptivo transversal. Fueron reclutados 642 futbolistas entre 13,0 y 18,9 años. Fueron medidas masa corporal, estatura, altura tronco-cefálica, pliegues cutáneos tricipital y subescapular. La madurez biológica fue determinada por la edad de pico de velocidad de crecimiento (EPVC) y el porcentual de masa grasa fue estimado por ecuaciones de regresión. Los percentiles de referencia fueron calculados por el método LMS. Resultados: Los valores de R2 para edad cronológica fueron menores (MG=0,07% y MLG=0,13%) en comparación con los valores para la edad biológica (MG=0,31% y MLG=0,50%). Fueron calculados 11 percentiles (p3, p5, p10, p15, p25, p50, p75, p85, p90, p95 y p97) para la MLG y MG. Conclusión: La edad biológica (EPVC) es un predictor mejor de la MLG y de la MG que la edad cronológica. Las referencias propuestas pueden servir para monitorizar la composición corporal de jóvenes futbolistas chilenos. Nivel de evidencia II; Estudio de diagnóstico .

RESUMO Objetivo: Analisar se a massa gorda (MG) e a massa livre de gordura (MLG) devem ser avaliadas pela idade cronológica e/ou pela idade biológica, e propor curvas para classificar a composição corporal de jovens futebolistas chilenos. Métodos: Elaborou-se um estudo descritivo transversal. Foram recrutados 642 futebolistas entre 13,0 e 18,9 anos. Massa corporal, estatura, altura tronco-cefálica, dobras cutâneas tricipital e subescapular foram medidas. A maturação biológica foi determinada pela idade de pico de velocidade de crescimento (IPVC) e o percentual de massa gorda foi estimado por equações de regressão. Os percentis de referência foram calculados pelo método LMS. Resultados: Os valores de R2para idade cronológica foram menores (MG = 0,07% e MLG=0,13%) em comparação com os valores para a idade biológica (MG = 0,31% e MLG = 0,50%). Foram calculados 11 percentis (p3, p5, p10, p15, p25, p50, p75, p85, p90, p95 e p97) para a MLG e MG. Conclusão: A idade biológica (IPVC) é um preditor melhor da MLG e da MG do que a idade cronológica. As referências propostas podem servir para monitorar a composição corporal de jovens futebolistas chilenos. Nível de evidência II; Estudo de diagnóstico .

Entrenamiento de los doctorandos para el dominio del gestor bibliográfico EndNote en un nivel avanzado / Training aspiring PhDs in the advanced use of the reference manager EndNote

La elaboración y la gestión de las referencias bibliográficas en el proceso de investigación es una tarea de alta importancia. Esta actividad continúa siendo una dificultad para muchos investigadores, a pesar del desarrollo informático vinculado a ella. El acceso y el uso de la información mediante Internet es una constante premisa en la investigación actual que requiere, con inmediatez para los investigadores, del avance de sus habilidades para la gestión bibliográfica, acorde con los nuevos adelantos técnicos. Los gestores bibliográficos son herramientas informáticas que ofrecen servicios automatizados para la organización bibliográfica, las cuales son conocidas a partir de otras publicaciones. Uno de los gestores más difundidos y utilizados es el EndNote, que se retomó nuevamente en esta investigación con una población de 23 doctorandos de la Universidad de las Ciencias Informáticas (UCI), con el objetivo de revelar los resultados obtenidos en la implementación de un entrenamiento de los doctorandos para el desarrollo de las habilidades de nivel avanzado. Como resultado se propusieron tres niveles de acciones para el dominio de esta herramienta que respondían al nivel de complejidad de las funcionalidades del software: básico, avanzado y experto. En el grupo de doctorandos del grupo UCI se evidencia un saber y un saber hacer en las acciones y operaciones del EndNote, superiores al diagnóstico inicial, que evidencia el desarrollo de un nivel básico a un nivel avanzado(AU)

Development and management of bibliographic references is a very important task in the research process. This activity continues to be a challenge for many researchers, despite the progress achieved in the field in terms of computer support. Access to and use of Internet-based information is a permanent premise in current research requiring immediacy in the enhancement of researchers' reference management skills, in keeping with recent technical advances. Reference managers are computer tools offering automated services for the bibliographic organization of references obtained from other publications. One of the most widely disseminated and commonly used managers is EndNote, which was revisited in the present study with a population of 23 aspiring PhDs from the Information Sciences University (UCI), with the purpose of revealing the results obtained by the implementation of a training program for the development of advanced skills intended for aspiring PhDs. As a result, three levels of actions aimed at the command of this tool were proposed: basic, advanced and expert, reflecting the degree of complexity exhibited by the functions performed by the software. The aspiring PhDs in the UCI group showed better knowledge and know-how about EndNote actions and operations than in their initial diagnosis. This was evidence of their progress from a basic to an advanced level(AU)

Referencias internacional y nacional, su uso en el estudio del crecimiento y la maduración física / International and national references, their use in the study of growth and physical maturation

Los factores genéticos y ambientales interactúan durante todo el crecimiento. La talla final adulta, el ritmo o tempo de crecimiento y maduración, así como la maduración sexual, esquelética y dental, tienen una transmisibilidad entre 41 y 71%. El estirón puberal ocurre un año antes en africanos que en europeos y los asiáticos son intermedios. Esta heterogeneidad puberal dificulta el uso de una referencia internacional en esta etapa, aunque su valor al permitir la comparabilidad entre poblaciones es indiscutible, así como el hecho que no todos los países pueden desarrollar sus propias referencias. En la Región Latinoamericana, Argentina, Cuba y Venezuela desarrollaron referencias hace muchos años y recientemente, Colombia, Ecuador y Perú. En Venezuela, se realizó el Estudio Nacional de Crecimiento y Desarrollo Humano (ENCDH) y el Estudio Longitudinal de Caracas (ELAMC) para establecer patrones de referencia, relevantes debido a la maduración más temprana y a las diferencias significativas en crecimiento y maduración con los anglosajones. Así mismo se elaboró el Atlas de Maduración Ósea del Venezolano y se han construido Curvas para uso Clínico integrando ambos estudios. Debido a la disparidad en el uso de referencias- internacionales y nacionalesse está planificando un estudio multicéntrico, denominado PRONNA, de la línea de investigación sobre Crecimiento y Desarrollo en Niños y Adolescentes (CDNNA) del Grupo Transición Alimentaria y Nutricional (grupo TAN) para la escogencia definitiva de las referencias a ser usadas(au)

Genetic and environmental factors interact during growth. Final height, tempo of growth, sexual, skeletal and dental maturation have between 41 and 71% heritability. The puberal spurt occurs one year earlier in Africans than in European descendants, Asiatic are intermediate. This pubertal heterogeneity difficult the use of an international reference during this period, although its importance in the comparability of prevalences is unique, as well as the fact that many countries are unable to develop their own references. In the Latin American Region, Argentina, Cuba and Venezuela have long--standing references, Colombia, Ecuador and Perú only recently. In Venezuela, due to the earlier maturation and differences from puberty onwards with anglosaxons, the National Growth and Development Study and the Caracas Longitudinal Study were developed in order to obtain growth charts. Both studies integrated for Clinical Use dual use charts: an Atlas for Bone Maturity Asessment is also available. Due to the multiple use of references (national as well as international) a multicenter national study-PRONNA- is being planned in order to decide which reference is most adequate. This is part of the Growth and Development Research line of study of TAN Group (Food and Nutritional Transition Group)(AU)

El desempeño del personal de Enfermería durante la pandemia de la COVID-19 / The nurses´ performance during the COVID-19 pandemic

RESUMEN Introducción: Durante el periodo de pandemia por la COVID-19 la profesión de Enfermería ha adquirido un total protagonismo. Objetivo: Ofrecer un referente teórico en relación con los cuidados de Enfermería durante la atención a pacientes con esta enfermedad. Método: En la Universidad de Ciencias Médicas Guantánamo durante el primer semestre de 2020 se realizó una revisión bibliográfica narrativa. Se ejecutó el análisis de artículos originales y revisiones sistemáticas que incluyeron información en relación con la COVID-19 y el desempeño de Enfermería durante esta pandemia. La búsqueda se efectuó consultando las bases de datos Pubmed, Infomed, y SciELO, sin restricción de fecha, en los idiomas español e inglés. Se utilizó el buscador Google Scho lar, y las palabras clave y conectores: COVID-19 AND Nursing care; SARS-CoV-2 AND Nursing care, y los términos en español. La extracción de datos se realizó según una planilla que resumió las preguntas de interés de acuerdo al objetivo de la revisión. Resultado: Se sistematizaron referentes teóricos que sustentan el liderazgo de la profesión de Enfermería en la atención al paciente con sospecha o confirmación de esta enfermedad. Se expresan las acciones esenciales que este profesional debe dar cumplimiento durante la atención a este tipo de paciente. Conclusiones: Se revela y argumenta el protagonismo de la profesión de Enfermería durante el periodo de la citada pandemia, y se ofrece una compilación de las acciones esenciales de este personal en la atención a los pacientes con esta enfermedad.

ABSTRACT Introduction: During the COVID-19 pandemic, nursing profession has gained total prominence. Objective: To offer a theoretical reference concerning nursing care in patients tested positive for COVID-19. Method: A narrative review was conducted in the University of Medical Sciences, Guantanamo, in the first semester of the year 2020. An analysis of original articles and systematic reviews that included information related to COVID-19 and nurses´ performance during the COVID-19 pandemic was conducted. This search was carried out by consulting the following databases, Pubmed, Infomed, and SciELO, without date restriction, and in the two languages, Spanish and English. Google Scholar was the web search engine used, and the keywords and links used were: COVID-19 and Nursing care; SARS-CoV-2 and Nursing care and and their corresponding terms in Spanish. Data gathering was done according to a spread sheet that summarized the questions of interest according to the objective of the review. Results: The theoretical references that support the leadership of nurses in the care of suspected or confirmed COVID-19 patient were systematized. The essential actions that this professional must comply with during the care of this type of patient are expressed. Conclusions: the leading role of the nursing professionals during this pandemic is revealed and argumented, and it is offered a compilation of the essential actions of these personnel in the care of patients with this disease.

Fundamentos teóricos de la preparación del estudiante de Estomatología en función de la educación para la salud bucal periodontal / Theoretical foundations of the dentistry students preparation in terms of education for the periodontal oral health

RESUMEN Introducción: La aspiración de egresar un estomatólogo general suficientemente preparado para resolver los problemas de salud bucal periodontal más generales y prevalentes es una exigencia social que se revela en el actual plan de estudio de la carrera de Estomatología. Objetivo: Elaborar unos referentes teóricos de la preparación del estudiante de Estomatología en función de la educación para la salud bucal periodontal. Método: De enero a julio de 2020, en la Facultad de Estomatología de la Universidad de Ciencias Médicas Guantánamo se realizó una revisión narrativa sobre el tema a través de una búsqueda en bases de datos electrónicas (Biblioteca Virtual en Salud, LILACS, PubMed, SciELO, REDALYC, Scopus). Se sistematizaron referentes teóricos que sustentan la preparación del estudiante de Estomatología en función de la educación para la salud bucal periodontal. Conclusiones: Se evidencia la necesidad de esta preparación dada su implicación en el modo de actuación profesional para una Atención Bucal Periodontal Integral. Las bases para esta finalidad emergen de la conjugación armoniosa de referentes filosóficos, sociológicos, legales, psicológicos, pedagógicos y didácticos en función de la práctica de la profesión.

ABSTRACT Introduction: The aim to graduate a general dentist with a high standard in knowledge to solve the most general and prevalent periodontal oral health issues is a social demand that is revealed in the current study program of dentistry major. Objective: To elaborate some theoretical references concerning dentistry student preparation in terms of education for periodontal oral health. Method: From January to July 2020, at the Facultad de Estomatología in the Universidad de Ciencias Médicas Guantanamo, a narrative review on the subject was carried out through a search in electronic databases (Virtual Health Library, LILACS, PubMed, SciELO, REDALYC, Scopus). It was systematized all the theoretical references that support the preparation of the dentistry students in terms of education for periodontal oral health. Conclusions: It is evident the necessity of this type of training due to its implication in the way to the best professional performance for an integral oral care. The foundations for achieving this goal emerge from the harmonious conjugation of philosophical, sociological, legal, psychological, pedagogical and didactic referents, in accordance to the practice of the profession.

Pattern of ophthalmic referral from primary healthcare centres to secondary and tertiary hospitals in Qassim Province, Saudi Arabia

Background: References of patients with ocular diseases are an indirect indicator that reflects integration of primary eye care into primary health care system. The study reviewed the ophthalmic references from four randomly selected primary health care centres to ophthalmic unit of secondary and tertiary hospitals in Qassim Province of Saudi Arabia.Methods: This was a retrospective health record review study was undertaken at four PHC centres in Qassim region during the year 2017. All cases referred for eye care from January 2015 until December 2016 were included. Prevalence of ophthalmic reference, profile of ophthalmic patients and ophthalmic diagnosis were analysed.Results: From primary health care centres, 423 eye cases from 1,387,996 population of catchment area were referred. The annual prevalence of eye reference was 1.5 per 10,000. Vision screening and diabetic retinopathy evaluation comprised of 55.5% of total reference.Conclusions: Poor reference pattern from primary health care centers to secondary and tertiary eye centre suggest urgent and strong need of implementing primary eye care in the primary health care centres of Saudi Arabia. Referral of simple eye cases are increasing the workload of ophthalmologists and can delay urgent referrals like cases of diabetic retinopathy screening.

Clarificar para Otro: Seis Prácticas Conversacionales Generativas de Cambio Terapéutico desde la Teoría del Cambio Subjetivo / Clarifying for an Other: Six Conversational Practices to Foster Therapeutic Change from a Subjective Change Theory Perspective

Resumen Desde la teoría del cambio subjetivo en psicoterapia, este estudio de caso constructor de teoría examina cualitativamente el proceso de cambio de una terapia exitosa. El estudio caracteriza micro-prácticas conversacionales que aparecen en episodios de cambio (EC). Los EC son segmentos de conversación teóricamente vinculados al cambio terapéutico, dado que en ellos aparecen indicadores genéricos de cambio en tres niveles: entrada, proceso, y salida. Se exploraron aquí los 16 episodios conteniendo indicadores genéricos de proceso (nivel 2). Como resultado se describen seis supuestos terapéuticos que facilitaron el logro de autorreferencias preferidas (ARP) en los EC de proceso. Se discute cómo esta caracterización contribuye a comprender la elaboración (subjetiva) de una "teoría" sobre el propio cambio terapéutico como resultado del proceso (intersubjetivo) de clarificar y validar ARP para y con el terapeuta. En este sentido, el estudio permite dar mayor especificidad a la teoría del cambio subjetivo desde el punto de vista del proceso conversacional que con-instituye o legitima el cambio.

Abstract Drawing from the theory of subjective change in psychotherapy, this theory-building case study examines one successful therapeutic change process. The study characterizes conversational micro-practices featuring in segments of conversation theoretically linked to therapeutic change called change episodes (CE), containing three types of observable generic indicators of change: input, process, and output. For this study the 16 CE containing indicators of the second level (process) were examined. Six conversational practices involving six therapeutic assumptions are presented as a result of the study, which were consequential in discursively accomplishing preferred self-references (PSR) within CE related to process. Given that generating a "subjective theory" about the client's own change process emerges as a byproduct of conversationally clarifying PSR for and with the therapist (i.e., intersubjective validation), this study contributes further specifying the theory of subjective change.

Osteoartrosis. Una revisión de literatura / Osteoarthrosis A literature review

Introducción: la osteoartrosis es la más frecuente de las enfermedades articulares. Objetivo: exponer los referentes bibliográficos que actualmente se refieren a la osteoartrosis en el marco de la revisión de literatura realizada. Desarrollo: como síndrome anatomoclínico se identifica por dolor mecánico que usualmente se relaciona con rigidez y que provoca poco a poco una pérdida o mengua de la función articular. Diversos factores de riesgo se relacionan con el progreso de esta enfermedad entre los que destacan, además de la edad y el sexo femenino, la obesidad, los microtraumas repetitivos en la práctica de determinados deportes y el cumplimiento de actividades profesionales específicas. Conclusiones: el tratamiento de la osteoartrosis debería ejecutarse a nivel de medicina familiar, tanto en el componente preventivo, como en el del control y manejo conservador, instruyendo al paciente en sus cuidados y acciones diarias y operando esquemas de medicamentos, ejercicios, apoyos funcionales como rodilleras, bastones y andadores. La educación médica debe asumir este paradigma, y no solicitar acto seguido la interconsulta a la especialidad cuando el paciente no responde, sin tener en cuenta que el manejo del paciente con artrosis se encuentra distante de la prescripción farmacológica(AU)

Introduction: osteoarthrosis is the most frequent joint disease. Objective: to expose the bibliographic references that currently refer to osteoarthrosis in the framework of the literature review carried out. Development: as anatomoclinic syndrome is identified by mechanical pain that is usually related to stiffness and that gradually causes a loss or decline of joint function. Several risk factors are related to the progress of this disease, among which stand out, in addition to age and female sex, obesity, repetitive microtrauma in the practice of certain sports and compliance with specific professional activities. Conclusions: treatment of osteoarthrosis should be carried out at the level of family medicine, both in the preventive component, as well as in the control and conservative management, instructing the patient in his daily care and actions and operating medication schemes, exercises, functional supports such as knee pads, canes and walkers. The medical education must assume this paradigm, and not immediately request the interconsultation to the specialty when the patient does not respond, without taking into account that the management of the patient with osteoarthritis is distant from the pharmacological prescription(AU)

Determinats of the distamce covered during a six-minute walk test in patients with chronic heart failure / Determinantes da distância percorrida durante teste de caminhada de seis minutos em pacientes com insuficiência cardíaca crônica

Background: The evaluation of the functional capacity of patients with chronic heart failure (HF) by means of the distance covered in the six-minute walk test (6MWT) has assumed great importance, since the 6MWD is a predictor of mortality and hospitalization in this population, however the determinants of better distance traveled in patients with HF are little explored, especially in the Brazilian population. Objective: To evaluate the determinants of 6MWD in patients with chronic HF. Methods: A cross-sectional study was performed with 81 HF patients in outpatient treatment. 6MWD was used as the outcome variable and sociodemographic, clinical, physical-functional and emotional data were submitted to multiple regression analysis using the stepwise method with a significance level of 5%. Results: Mean age of participants was 56.71 years; the 6MWD showed a bivariate correlation with age (r = -0.27, p = 0.01), maximal inspiratory pressure (r = 0.42, p < 0.01), maximal expiratory pressure (r = 0.36, p < 0.01), handgrip strength (r = 0.38, p < 0.01), Borg scale (-0.22, p = 0.04), Charlson index (r = -0.25, p = 0.02) and modified Medical Research Council (mMRC) dyspnea scale (r = -0.42, p < 0.01). In the multivariate analysis, the variables gender (p = 0.001), age (0.004), forced vital capacity (FVC) (p = 0.016) and mMRC (p = 0.001) simultaneously explained 37% of variance in the 6MWD. Conclusion: Higher levels of dyspnea on daily life activities, female sex, older age and lower forced vital capacity are determinants of a shorter 6MWD in patients with chronic HF

Consistency Analysis of “Imprinting Templates” of Chinese Medicine Preparations Based on Dynamic Volatile Components in Houttuyniae Herba / 中国实验方剂学杂志

Objective:The homogeneity regularity of "imprinting templates" of compound preparation of traditional Chinese medicine(TCM) was revealed, which provided the basis for effectively controlling the quality of compound preparation of TCM, by clarifying the dynamic changeability in number and content of volatile ingredients in different batches of Houttuyniae Herba. Method:The volatile oil of Houttuyniae Herba was extracted by steam distillation.The volatile components in 11 batches of Houttuyniae Herba were determined by GC-MS(electron ionization, ion source temperature of 230℃, detection range of m/z 40-500) combined with literature and ChemicalBook database.The relative content of each component was calculated by peak area normalization method and analyzed by the total quantum statistical moments of fingerprint. Result:There were only 15 common ingredients in the volatile oil from 11 batches of Houttuyniae Herba, accounting for 3.35%of total number and 73.94%of total content, while the number of non-common ingredients was 433, accounting for 96.65%of total number.However, the RSD of total quantum first moment of GC-MS fingerprint was 6.8%, the RSD of total quantum second moment was 14.8%(RSD of standard deviation was 7.4%), and the RSD of similarity of total quantum statistical moment was 3.8%.The type and content of volatile ingredients in Houttuyniae Herba were heterogeneous, but their chromatographic behavior of GC-MS fingerprint was uniform, the whole "imprinting templates" was similar. Conclusion:The total quantum statistical moment(similarity) of TCM fingerprint is applicable to quality control of dynamic Chinese medicines, which will play a breakthrough role in the study of homogeneity and stability of material reference and compound preparation for ancient classical formulas.