Permeability to blood-brain burrier of / 解剖学报

Objective To investigate the optimal time and mechanism of nerve growth factor(NGF)crossing the blood-brain barrier (BBB) under cerebral ischemia in rats through focal cerebral ischemia experiments in rats, and to provide a new way for the clinical application of NGF. Methods A total of 65 healthy Sprague-Dawlay (SD) male rats were prepared by using a modified suture method to prepare focal cerebral ischemia models. Rats were injected with