Clinical observation of the axial length and corneal curvature after silicone oil removal combined with cataract surgery in high myopia patients / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To explore the postoperative axial length(AL)and corneal curvature(K)shift in high myopia silicone oil patients complicated cataract after silicone oil removal combined with cataract surgery as well as the relationship.<p>METHODS: From August 2020 to November 2020 in the Affiliated Eye Hospital of Nanchang University, 45 patients(48 eyes)with silicone oil eye complicated cataract were divided into 2 groups: 20 eyes of 20 patients(refraction ≥-6.00D and AL ≥26mm)in high myopia group and 28 eyes of 25 patients(refraction < -6.00D or AL <26mm)in non-high myopia group. Record the general information and IOL-Master measurement data AL and K, statistical analysis was performed. <p>RESULTS: There was no difference in preoperative and postoperative K value of two groups(all <i>P</i>>0.05). The AL of the patients in the high myopia group was 28.35±1.68mm after silicone oil removal combined with cataract surgery, which was shorter than 28.08±1.53mm before the operation(<i>P</i><0.001), yet not statistically significant in non-high myopia group(<i>P</i>>0.05). The median ΔAL of patients in the high myopia group was \〖-0.28(-0.44, -0.08)\〗 compared with the non-high myopia group \〖-0.06(-0.20, 0.15)\〗, which was statistically different(<i>P</i><0.05), but no significant difference in both ΔK(<i>P</i>>0.05). There was no correlation between |ΔAL| and |ΔK|, or and preoperative K values(<i>P</i>>0.05)in two groups. Preoperative AL was moderately positive correlated with |ΔAL| in the high myopia group(<i>r</i>=0.702, <i>P</i>=0.01), but not in the non-high myopia group(<i>P</i>>0.05).<p>CONCLUSION: There was no significant shift in K value of high myopia group with silicone oil eye complicated cataract after the silicone oil removal combined with cataract surgery. The longer preoperative AL in high myopia group, the more likely become shorter after surgery, meanwhile the longer AL, the greater AL shift.

Effect of Danggui-Chuanxiong herb pair on JAK-STAT signaling pathway in rats with cerebral ischemia/reperfusion injury / 中国药理学通报

Aim To explore the regulatory effect of Danggui-chuanxiong herb pair (GX) on JAK-STAT signaling pathway in rats with cerebral ischemia/reper-fusion injury (I/R). Methods The I/R injury rat model was constructed by modified suture occlusion method. After 24 hours of perfusion, Zea Longa scoring method was used to score the neurological function, TTC staining to detect the cerebral infarct volume of rats, HE staining to observe the pathological changes of brain tissues, the biochemical method to determine the MDA, SOD, GSH-Px expression, ELISA to detect the expression of NF-κB, VEGF, ICAM-1 and PAH in brain tissues, and immunohistochemical method to detect JAK2, p-STAT3, AKT And ERK1/2 expression of the brain tissue ischemic penumbra area. Results Compared with sham group, model rats had severe neurological damage, larger cerebral infarction, necrosis, edema, inflammation, disorder of nerve cell arrangement, abnormal cell enlargement, vacuole-like changes, neuron reduction and other pathologies in brain tissues. The expression JeveJs of MDA, NF-κB, VEGF, PAI-1 and ICAM-1 in brain tissues of model group significantly increased, and the expression levels of GSH-Px and SOD were significantly reduced. Compared with model group, the neurological scores of rats in GX

When is the ideal time to remove cerclage in cases requiring cesarean hysterectomy for placenta accreta spectrum?

Placenta accreta spectrum (PAS) presents one of the highest risks to pregnancy and often requires a cesarean hysterectomy for management, but the challenges associated with this surgery often cause severe obstetric haemorrhaging and high rates of maternal morbidity. Shirodkar cerclage is usually performed in cases with cervical insufficiency, a short cervix with previous preterm birth, etc., to decrease the preterm birth rate. It is recommended that Shirodkar cerclage is removed when the patient approaches term, but the ideal timing of removal for patient for whom cesarean hysterectomy is planned is not clear. Here, authors present a case of PAS in whom Shirodkar cerclage that was difficult to remove at the timing of cesarean hysterectomy. After cesarean hysterectomy, the patient had a vaginal abscess and required antibiotic therapy for approximately two weeks. In the light of our case, authors discuss the timing of removal of cerclage in the cases of PAS.

Coronary Heart Disease Phlegm-blood Stasis-stagnation-deficiency Innovation Theory and Clinical Application Based on Complex System / 中国实验方剂学杂志

There exits a trend of treatment for coronary heart disease(CHD) in terms of Chinese medicine(CM) in history,from warming Yang and dispelling cold,moving Qi and dissolving phlegm to invigorating blood and dissolving stasis,whose time-space development accords to the theory of complex system.Targeting the contemporary population of CHD,phlegm-blood stasis-stagnation-deficiency theory is proposed to direct clinical application to further improve effectiveness.From the perspective of theory,blood stasis-stagnation is the basic pathogenesis of CHD that runs through the whole period in the advance of CHD,while phlegm has been changing the feature of CM Zheng of CHD population with the development of the society,and nourishing the body according to the type of deficiency might delay the process of growing older,postpone the occur of disease and hinder the advance of disease,which genuinely differs from modern medicine to render the superiority of CM to work out the challenges of CHD.As for the clinical application,the treatment options could consider invigorating blood,dissolving stasis and removing stagnation as the basic method,such as CHD formula 2,Xuefu Zhuyutang,Zhizi Chitang and Danggui Niantongtang could be used in varied period of CHD.Moreover,boosting the body by herbal medicine could regulate the routine of body,then to prevent CHD and fear down the advance of CHD,for instance,Codonopsis Radix,Astragali Radix,Liuwei Dihuang pills,Zuoguiyin and Youguiyin.Furthermore,balmiest herbs could not only dissolve phlegm,unblock the meridian and relieve pain,but also calm the mind and eliminate the anxiety.For example,Aquilariae Lignum Resinatum,Santali Albi Lignum and Moschus could be used handily in the treatment of CHD.

Methods of removing failed implants / 华西口腔医学杂志

Implant restoration has become one of the most regular methods of restoring dentition defect or edentulous. Implant placement and osseointegration are partly unreserved (fracture, implant is not in the correct three-dimensional position and cannot be repaired, peri-implantitis-affected nonmobile implants) need to be removed. This article reviews the different methods of removing implants and discusses the limitations of each method, as well as the complications that may occur during the procedure.

Establishing A Method to Rapidly Remove Glycerol in Frozen Red Blood Cells / 现代检验医学杂志

Objective To establish a method to rapidly remove glycerol in frozen red blood cells(RBC).Methods The glycerol in frozen RBC was removed by using three-step method as following:the frozen RBC were diluted by adding salt solution with high concentration.The salt solution was removed through centrifugation.The RBC were resuspended in normal saline of corresponding volume.Three-step method could acbieve the quick removal of glycerol by controlling tbe concentration salt water and action time.The indexes of hemoglobin,free hemoglobin,glycerol residue,residual white blood cell(WBC) and hematocrit of frozen-deglycerolized RBC were compared between conventional and improved methods.Results The traditional method to remove glycerol needed 1h approximately,while the three step method only needed 15 mins approximately,greatly shortening the time and improving the efficiency.The related tests for removing glycerol RBC,except hemoglobin content was slightly lower than the "The quality requirements for whole blood and blood components (2012 edition)",the rest of them all meeted the requirements.Conclusion The three-step method has the advantages of short time and high cfficiency.However,it still needs to be further improved and optimized to make the quality of product meet the national standard.

Professor SUN Wei's Clinical Experience in Treating Nephritic Hematuria / 浙江中医药大学学报

[Objective]The article summarizes the experience of Professor SUN Wei in treating nephritic hematuria.[Methods]The article discusses the clinical experience of Professor SUN Wei in the treatment on nephritic hematuria from the methods of learning from his daily treatment in inpatient and outpatient department,reading relative books and articles,recognition from the study of ancient classics,from etiology and pathogenesis,treatment,illustrating Professor's medication experience in the treatment of nephritic hematuria and with a case for evidence.[Results]Professor SUN Wei believes that the basic pathogenesis of nephritic hematuria is deficiency of the kidney with dampness heat and blood stasis,he creates the therapeutic modality of tonifying the kidney and promoting blood circulation and clearing away the damp-heat,he emphasizes reinforcing kidney and spleen, clearing heat and dampness,promoting blood circulation,conditioning the blood,he considers that the kidney Qi and Yin deficiency come first among kidney deficiency,long-term hematuria should not to be over-astringed.Professor SUN Wei is apt at the use of the herbs,all of these usually lead to good curative effect.[Conclusion]Professor SUN Wei's clinical experience in treating nephritic hematuria from tonifying the kidney and promoting blood circulation and clearing away the damp-heat is well worth extending in clinic for it always has significant effect.

Professor SUN Yiqiu's Clinical Experience in Treating Allergic Cough / 浙江中医药大学学报

[Objective] To discuss the academic point of view and clinical experience of Professor SUN Yiqiu in diagnosing and treating allergic cough in children. [Methods]The data were collected by method with sommelier diagnosis,from the pathogenesis and treatment aspects of academic ideas of Professor SUN Yiqiu in treatment of children allergic cough and clinical experience, the prescription and Chinese medicine conditioning characteristics are summarized,with case for evidence.[Results]Professor SUN Yiqiu believes that wind invading the lung is the forerunner of this disease,the key pathogenesis of lung deficiency and pathogen retention,to remove evil is the basic treatment principle;clinical value of cure from the"wind",advocate"Yufeng"Quxie law to improve their body resistance,thus reducing the incidence,alleviate symptoms,play the role of qufengzhike;clinical use of modified Yuping Feng Pulvis in treatment of this disease, on the basis of addition and subtraction, using both specimens, prevention concept, emphasizing the combination of syndrome differentiation and disease differentiation,syndrome differentiation and symptomatic symptoms a combination gets significant effect. [Conclusion]Professor SUN Yiqiu's experience in the treatment of allergic cough in children is clinically effective and can be used for clinical reference.

Activating blood biological potency assay and chemical fingerprint chromatogram applied to quality evaluation of rhubarb / 药学学报

The biological potency assay and chemical fingerprint chromatogram were applied to quality evaluation of rhubarb. Using the biological potency as indicators, we evaluated the differences in quality of multiple batches of rhubarbs and related products. Using the platelet aggregation analyzer, we determined platelet aggregation rate in the different rhubarbs preparations, and calculated the biological potency based on the simplified probit principle. UPLC was adopted to establish the fingerprint spectra for rhubarbs. The spectral efficiency correlation analysis between chromatograms and biological potencies were conducted using the double variables of SPSS 22.0 software. We used three chemical composition to verify the potency. The biological potency results suggest that Rheum palmatum has a more potent activity than Rheum tanguticum, and wine-treated rhubarb had a higher potentcy than charred. We identified 10 elements in the Fingerprint Spectrum. The relevant elements including rhein-8-O-β-D-glucoside, emodin-8-O-β-D-glucoside and rhein have the strongest activity in the inhibition of platelet aggregation. In conclusion, this study provides a analytical method for rhubarb biological potency based on determination of the maximum antagonism rate model. The rhein may be the effective substance. It may serve as a reference in the quality control of wine processed rhubarb products.

Clinical observation on treatment of coronary heart disease by promoting blood circulation and removing stasis / 中国生化药物杂志

ObjectiveAnalyze the mechanism of traditional Chinese medicine Salvia miltiorrhiza in treating coronary heart disease (CHD).MethodsThe animal experiment using actual research, namely the selection of rat isolated heart perfusion model, rat model of myocardial ischemia and ventricular tachycardia in rabbits model, then the effects of different animal groups in hemodynamics, coronary flow, serum superoxide dismutase (SOD) content, malondialdehyde (MDA) the results of the content.ResultsAfter treatment, the content of SOD was significantly increased and the content of MDA was significantly decreased in the treatment group, and the difference between the two groups was statistically significant (P<0.05).ConclusionTraditional chinese medicine Salvia miltiorrhiza has significant effect on the treatment of coronary heart disease, which is beneficial to the recovery of patients' condition, and is worthy of clinical application.

"Experience in Treating Acute Coronary Syndrome from the Viewpoint of ""Heat and Blood Stasis and Poison Damage Heart Nutrient""" / 中国中医药信息杂志

Abtract: Acute coronary syndrome is a common clinical and frequently occurring disease, belonging to the chest discomfort, heartache, and true heart pain of TCM category. The clinical observation shows that the heat and blood stasis, and poison damage heart nutrient is one of the important mechanisms of triggering coronary syndrome. Therefore, the method of promoting blood circulation to remove meridian obstruction and the Qing Ying detoxication was established as the basic treatment, and Danshen Tongluo Jiedu Decoction is applied as the main formula. According to the different types of disease and syndrome differentiation, flexible modification can achieve good efficacy. It is expected that these will provide new ideas and methods for clinical treatment of acute coronary syndrome.

Professor WANG Peijuan's Experience in Treating Polycystic Ovary Syndrome / 浙江中医药大学学报

[Objective]Investigating Professor WANG Peijuan's clinical experience in treating PCOS from studying the kidney. [Method] This paper mainly studied by arranging and researching the tutor's theory and experience about treating PCOS that based on the practice in clinic with the teacher as a self perception,the collection about the PCOS cases of tutor's clinical treatment and the analysis of national and international relative literature combined with self-awareness. [Result]Professor WANG thinks that PCOS is the disorder of qi and blood and the transformation failure of kidney-Tiangui-Chongren-uterus, which leads to phlegm and blood stasis, blocking in the uterus and making menstruation lose its inhere periodicity. The disease is of the kidney deficiency and phlegm stagnation syndrome.[Conclusion]Professor WANG holds that to use the method of tonifying kidney properly and attach importance to the three categories of etiologic factors will be effective to the treatment of PCOS. Her experience can provide the basis for diagnosis and treatment about the disease.

FAN Wenhu 's Experience in Treating Dampness Prevalent Diseases with Flexible Use of Wetting Method / 浙江中医药大学学报

[Objective]Analysis of the famous doctor FAN Wenhu treatment of dampness prevalent diseases experience with a view to the clinical treatment of it to provide reference.[Methods]By consulting the relevant FAN Wenhu's medical information and screening out the treatment of dampness prevalent diseases of his cases to further analyze and sum up his clinical experience in the treatment of it. [Result] It was found out that he was skilled in using wetting treatments for dampness prevalent diseases, which the wet wilt in the upper body used Qingzhen decoction to clear dampness wetting,the vomid malaria used Huopusini powder to regulate qi and dispel wet, the damp-heat invagination used Huopuwuling powder to activate yang to remove dampness. [Conclusion]FAN Wenhu was flexibled to use varieties of dampness methods in the treatment of dampness prevalent disease in order to eliminate wet evil and isolate hot evil.These cases had accurate effect and distinct treatment characteristics,it is worthy of reference.

Treating Chronic Atrophic Gastritis from Blood Stasis / 浙江中医药大学学报

[Objective] To explore the clinical experience of Professor ZHOU Xiaohong in treating chronic atrophic gastritis(CAG) from blood stasis.[Methods]Through the analysis of literature,tracing the source of the disease,following the teacher clinic and collecting relevant medical records,Professor ZHOU Xiaohong's clinical experience in treating CAG from blood stasis is summarized from the aspects of etiology,pathogenesis,treatment and so on.At the same time,the characteristics of the prescription of herbal are summarized,and exemplify that.[Result]Professor ZHOU Xiaohong thinks that blood stasis is the basic pathological factor of CAG.It plays an important role in the occurrence and development of this disease,and blood circulation and blood stasis should be carried through the whole process of clinical syndrome differentiation and treatment.ZHOU attachs importance to the application of drugs for promoting blood circulation to remove blood stasis,such as syndrome differentiation,disease differentiation,experience.In addition,another key view is the selection of drugs that can activate blood circulation to remove blood stasis,combining with modern research.The uhimatc result is to promote rcstoration of the gastric mucosa and absorption of local inflammation,enhance and improve the function of gastric mucosal barrier,reduce the degree of glandular atrophy,prevent cancer,and,thus significantly improve clinical efficacy.[Conclusion] Professor ZHOU Xiaohong has rich clinical experience and unique opinion in treatment of CAG.The clinical curative effect of CAG from the treatment of blood stasis is significant,which is worth learning and popularizing.

Activating blood circulation to remove stasis treatment of hypertensive intracerebral hemorrhage: A multi-center prospective randomized open-label blinded-endpoint trial / 中国结合医学杂志

<p><b>OBJECTIVE</b>To investigate the efficacy and safety of the Chinese herbal therapeutic regimen of activating blood circulation (TRABC) in treatment of hypertensive intracerebral hemorrhage (HICH).</p><p><b>METHODS</b>This was a multi-center prospective randomized open-label blinded-endpoint (PROBE) trial with HICH admitted to 12 hospitals. Totally 240 participants were randomized to the treatment group treated with TRABC in addition to conventional Western treatment or the control group with conventional Western treatment equally for 3 months. Primary outcome was degree of disability as measured by modified Rankin Scale (mRS). Secondary outcomes were the absorption of hematoma and edema, National Institutes of Health Stroke Scale (NIHSS) scores and patient-reported outcome measures for stroke and Barthel activities of daily living index. Adverse events and mortality were also recorded.</p><p><b>RESULTS</b>After 3 months of treatment, the rate of mRS 0-1 and mRS 0-2 in the treatment group was 72.5% and 80.4%, respectively, and in the control group 48.1% and 63.9%, respectively, with a significant difference between groups (P<0.01). Hematoma volume decreased significantly at day 7 of treatment in the treatment group than the control group (P=0.038). Average Barthel scores in the treatment group after treatment was 89.11±19.93, and in the control group 82.18±24.02 (P=0.003). NIHSS scores of the two groups after treatment decreased significantly compared with before treatment (P=0.001). Patient-reported outcomes in the treatment group were lower than the control group at day 21 and 3 months of treatment (P<0.05). There were 4 deaths, 2 in each group, and 11 adverse events, 6 in the treatment group and 5 in the control group.</p><p><b>CONCLUSION</b>The integrative therapy combined TRABC with conventional Western treatment for HICH could promote hematoma absorption thus minimize neurologic impairment, without increasing intracerebral hematoma expansion and re-bleeding.</p>

Research progress of anti-N-methyl-D-aspartate receptor encephalitis / 中华实用儿科临床杂志

Anti-N-methyl-D-aspartate receptor (NMDAR) antibody encephalitis is an autoimmune encephalitis manifesting subacutely with prominent aberrant movements and psychiatric symptoms,which associated with antibodies against NR1 or NR2 subunits of the NMDAR.The disease is not rare,early diagnosis and immune treatment can improve prognosis and reduce the recurrence.The epidemiology,mechanisms,clinical presentation,treatment and prognosis of the disease were reviewed in order to enhance the cognition of anti-NMDAR encephalitis.

Director He's Experience in Treating Ovarian Cancer / 浙江中医药大学学报

Objective]To sum up director He Ruoping's feature in recognizing ovarian cancer causa morbi and mechanism and clinical treatment rules; To explore the clinical experience of director He Ruoping treatment with ovarian cancer.[Method]By learning from director doctor He Ruoping for three years and combining my own clinical experience, from the etiology and pat hogenesis, it sums up the teacher He' s unique feature of by stages treatment of ovarian cancer, and with one case for detailed explanation.[Result]Teacher He advocates the combination of traditional Chinese medicine and western medicine, puts forward the principle of ovarian cancer.By the way of strengthening body resistance and eliminating evil, Teacher He adopts the help of invigorating the spleen and tonifying the kidney,supplementing qi and nourishing yin,soothing the liver and regulating qi,clearing away heat and toxic material,promoting blood circulation to remove blood stasis, softening firm scattered nodes,and water permeability wet for the main therapy in treatment of ovarian cancer and the curative effect is remarkable.[Conclusion] To take Teacher He' s experience for treating ovarian canceR from essence,replenishing qi and blood,removing turbidity can significantly relieve patients' clinical symptoms and improve patients' life quality.

Re-understanding of the Treatment of Ectopic Pregnancy from Blood Stasis / 浙江中医药大学学报

Objective] To explore the theoretical origin, clinical application method, effect and practical significance of the treatment of ectopic pregnancy with blood stasis. [Method] From blood stasis on the treatment by promoting blood circulation to remove blood stasis, Yiqi Yangxue Huayu Shapei, expelling blood circulation, method to eliminate the disease, stage of treatment, a reasonable choice of promoting blood circulation and removing blood stasis drugs in the treatment of ectopic pregnancy. [Results] From blood stasis on the treatment of ectopic pregnancy, it can accelerate the beta HCG negative, and speed up the ectopic pregnancy mass absorption, clinical curative effect significantly, the greatest degree of protection of fallopian tube integrity, improve blood circulation, and tubal function recovery, increase after treatment the chances of conception. [Conclusion] Qi stagnation, blood stasis and Qi deficiency and blood stasis are ectopic pregnancy basic pathogenesis, less empirical abdominal blood stasis is the essence of its pathogenesis. The existence of blood stasis in ectopic pregnancy of each type and disease development of the whole process, in the occurrence of the disease, and occupies an important position in the development, promoting blood circulation and removing blood stasis is the basic treatment, should be in clinical dialectical treatment of the whole process of fusion.

Clinical Experience in Treating Pregnancy Uterine Cavity Effusion by Tonifying Kidney to Remove Blood Stasis / 浙江中医药大学学报

Objective]To explore clinical experience in treating pregnancy uterine cavity effusion by tonifying kidney to remove blood stasis. [Method] With the study of TCM literature on pregnancy uterine cavity effusion, by combining with clinical practice, it expounds pathogenesis and treatment of syndrome differentiation of pregnancy uterine cavity effusion. [Result]The main pathogenesis of this disease focuses on kidney deficiency and blood stasis which can impair Chong and Ren channels,inducing insecurity of the fetal origin,so the clinical treatment principle centers on tonifying kidney to remove blood stasis,and the self-decoction that is the basic recipe may change with symptom, making the fetal origin secure. [Conclusion] Method of tonifying kidney to remove blood stasis is quite effective for pregnancy uterine cavity effusion in clinic,and it is worth further study.

"Study on the ""Quhan"" in Traditional Chinese Medicine Processing" / 浙江中医药大学学报

Objective] Study on the exact meaning of Quhan in traditional Chinese medicine processing. [Methods] Based on studying the ancient and modern Chinese literature, with Sichuan pepper as the breakthrough point, we can analyze Quhan method of processing and the role. [Results] The process of Quhan is a component of the water or oil that is contained in the internal drug, which is transferred to the surface of the drug by frying or heap stuffy, it can not simply be regarded as to remove the water or oil from the drug. A correct understanding of Quhan is practically significant for people to master some of the traditional Chinese medicine processing degree and improve the treatment result of the drug instead of removing the water or oil from the drug. [Conclusion] Quhan is the method that the liquid substance is free to the surface of traditional Chinese medicine processing, which can make the drug's effect better.