Diagnosis and management of primary retroperitoneal teratoma in 36 infants / 中华实用儿科临床杂志

Objective To investigate the clinical manifestations and surgical effectiveness of the primary retroperitoneal teratoma in infants.Methods The records of 36 patients were retrospectively reviewed who were diagnosed as primary retroperitoneal teratoma and treated at the Department of Pediatric Oncology,Guangzhou Women and Children's Medical Center between August 2015 and August 2017.The related data were collected,including gender,age,operation time,operational bleeding and tumor weight.All patients took the ultrasound,computed tomography (CT) before surgery,alpha-fetal protein (AFP) and human chorionic gonadotrophin(HCG) were detected during peri-operation period.All cases were classified into 0 to Ⅲ grades according to the Norris classification (27 patients of 0 grade,1 patient of Ⅰ grade,4 patients of Ⅱ grade,4 patients of Ⅲ grade).Results There were 9 males and 27 females in the study.All patients were treated surgically at the age of 11.4 months (7 days-7 years) on the average;the mean weight of incised tumor was 736.47 g (7.90-2 355.00 g);operation time was 2.88 hours (1.08-7.06 hours);the amount of bleeding during operation was 29.11 mL (2-150 mL).All patients received follow-ups for 6.56 months (9 days-23 months) on the average.Radiographs found that tumors in 25 patients (69.4％) were located in the left side of the abdominal cavity,and the rest of them were located in the right side.In addition,tumors in 30 patients (83.3 ％) were big enough to pass across the mid-line of the body.Average pre-operation AFP was 7 593.1 μg/L(1.7-80 000.0 μg/L),post-operation AFP was 1 339.5 μg/L(1.4-16 519.6 μg/L),and the difference was statistically significant (P =0.001);pre-operation AFP of the mature group was 5 439.6 μg/L(1.7-80 000.0 μg/L),post-operation AFP of the mature group was 1 130.6 μg/L(1.4-16 519.6 μg/L),and the difference was statistically significant (P =0.001);pre-operation AFP of the immature group [11 182.3 μg/L(17.4-80 000.0 μg/L)] was higher than that of the mature group,and the difference was statistically significant(P =0.006).On the final follow-up,AFP was mean 38.3 μg/L (1.4-352.4 μg/L);among them,AFP of the mature group was mean 14.3 μg/L (1.4-43.3 μg/L),the immature group was 78.4 μg/L(1.7-325.4 μ g/L),and the difference was statistically significant(P =0.028);AFP of 4 patients in the immature group who underwent chemotherapy was 54.9 μg/L (2.6-116.6 μg/L)on the average,lower than those of post-operation AFP of 265.2 μg/L (206.8-384.1 μg/L),and the difference was statistically significant (P =0.042).All patients were treated surgically,and 3 cases of them received laparoscope technique;no significant relationship was proved between time of surgery and the tumor weight,location,and Norris classification(all P ＞ 0.05).The incidence rate of the surgical complications was 42.1％,such as tumor rupture (6 patients),vascular injury (5 patients),digestive tract damage (4 patients) and incomplete incision (1 patient).There was no death case in the serials.Conclusions Primary retroperitoneal teratoma can be completely incised.However,the complications of surgery could appear in many cases.As a predictive index for the recurrence retroperitoneal teratoma,AFP can be diminished by chemotherapy following the surgery.

A Case of Adrenal Teratoma

Teratoma is a congenital tumor containing tissues derived from all germ layers. Teratoma in the region of the adrenal gland is a very uncommon retroperitoneal tumor. Only 7 cases of adrenal teratoma have been reported worldwide, but in Korea, no similar cases have been reported until now. This case report describes an adrenal teratoma in a 38-year-old healthy woman who was incidentally diagnosed with a left adrenal mass on abdominal ultrasonography during a medical inspection. Computed tomographic scans revealed a 9-cm heterogeneous circumscribed round mass, containing primarily fat tissue, and a solid calcification component in the left adrenal gland. Adrenal hormonal assessment results and biochemical markers for gonadal neoplasia were negative. Result of serum laboratory tests were normal. The patient underwent laparoscopic adrenalectomy. Histologic analysis confirmed the diagnosis of a mature teratoma; the obtained specimen measured 5 x 7 x 7.5 cm and weighed 267 g. The surface of the mass was smooth, and sebaceous tissue and hair with hard material were observed on the incisional surface. The patient was discharged on postoperative day 4, without complications. In this case report, we describe the incidental finding of a teratoma occurring in the adrenal gland region in a healthy woman; the teratoma was laparoscopically excised.

Thoraco-abdominal mature teratoma in a left diaphragmatic hernia.

This case describes a contiguous mediastinal and retroperitoneal mature teratoma in a congenital diaphragmatic defect, a combination that is hitherto unreported in literature. It substantiates embryological chronology of events during the cephalad migration of the primordial germ cells through the developing diaphragm, prior to its closure.

A case of retroperitoneal teratoma / 대한산부인과학회잡지

Retroperitoneal teratomas, which were found occasionally in children but very rarely in adults, occur mainly at the upper pole of left kidney and diagnosed after they grow very enormously. Authors experienced one case of about 20 cm-size retroperitoneal teratoma, which occurred to a 30-year-old postpartum woman at the left upper pole of kidney.

Primary Retroperitoneal Teratoma in the Infancy: Two cases report / 대한비뇨기과학회지

Retroperitoneal teratoma is comparatively rare and yet difficult to treat and predict the prognosis. Recently we experienced 2 cases of retroperitoneal teratoma in the infancy, which was suspected by radiologic investigation and confirmed by exploration and microscopic examination.

Primary Retroperitoneal Teratoma: A Case Report / 대한비뇨기과학회지

Retroperitoneal teratoma are comparatively rare and yet difficult to treat and predict the prognosis. A case of primary retroperitoneal teratoma in a 28-year-old woman is presented, which was suspected by excretory urography, ultrasonography and angiography, and then preoperatively diagnosed by computerized tomography.

Primary Retroperitoneal Teratoma: A Case Report / 대한비뇨기과학회지

Retroperitoneal teratoma is a rare condition in only 10% of all retroperitoneal primary neoplasm and about 200 cases has been recorded since Morgagni`s first description in 1961. Recently we experienced a case of huge retroperitoneal teratoma(18kg), which was suspected by clinical investigation and confirmed by exploration and microscopic examination.

Retroperitoneal Teratoma: A Case Report and Review of the Literature / 대한비뇨기과학회지

Retroperitoneal teratoma is generally recognized as a disease of childhood and about 150 cases have been reported on literatures since Morgagni described it in 1761 for the first time. A case is reported of retroperitoneal teratoma in s 5-month-old female infant. The literatures are reviewed.

A Case of Retroperitoneal Teratoma / 대한비뇨기과학회지

Retroperitoneal teratoma is a rare condition and less than 100 cases have been reported since Morgagni's first description in 1761. A 5 year-old girl with retroperitoneal teratoma is described. The literature is reviewed briefly.

A Case Report of Retroperitoneal Teratoma / 대한비뇨기과학회지

A case of retroperitoneal teratoma was presented in a 40-year-old Korean Male. The radiologic studies were evaluated a space occupying mass containing tooth like a density in the retroperitoneal region. Surgical removal of mass wag performed and histological finding was conformed the benign teratoma.