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Introduction: The ABO and Rh blood group systems are themost important blood group systems in Transfusion Medicine.This study was carried out with an objective to study thedistribution of ABO and Rh blood groups among voluntaryblood donors in Central Gujarat, India which is essential foreffective management of blood inventory.Material and Methods: The present retrospective studywas carried out at our blood centre. The data of presentstudy is from 01/06/2009 TO 31/12/2019. Total 398803voluntary blood donors were considered medically fit andaccepted for blood donation. ABO and Rh typing was doneby Manual Microplate Technique (June 2009 to August 2015)and automated blood group Immucor Galileo neo machine(September 2015 to December 2019) both forward and reverseblood grouping after validation at blood bank.Result: Out of 398803 blood donors B blood group was mostcommon(143408-35.96%) and the least blood group was ABBlood group (33631 – 8.43%). There were more Rh Positiveblood donors (372660 – 93.45%) as compared to Rh Negativeblood donors (26143 – 6.55%).Conclusion: The most common blood group among voluntarydonors was B positive and least common blood group was ABnegative.
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The result of this study show that the determination rate of the first screening test of Rhesus group D antigens negativity was 1.2%, where as the confirmation analysis decreased this rate to 1.18%. Similarly, the determination rate of the Kell K-antigen positivity rate was 0.9%. where as the confirmation test decreased this rate up-to ().X5%. These result show, that it is necessary to use confirmation test in routine diagnosis of blood sub-group determination. The Rh blood group system is of considerable importance in transfusion and clinical medicine. We have determined some clinically important red cell antigens such as C,c I), E,e in 97 Rh (+) blood donors, using the monoclonal antibodies "Erithrotest-Tsoliclon", produced at the Hematology company. Russian Federation. Among these Rh (•) blood donors prevail RIR2, R1R1 .R2R2 phenotypes accounting for 36.1%, 27.X% and 11.3% respectively. Among these Rh (-) blood donors prevail rr. rr'.rr" phenotypes accounting for 74%, 16% and 4% respectively.