A View of Supply of Single Donor Platelets in Korean Red Cross / 대한수혈학회지

BACKGROUND: The use of single donor platelets (SDPs) has been increased substantially worldwide. But in korea, SDPs are supplied only 11.5% of total platelets transfused and most of them collected in hospital blood center. Korean Red Cross blood center decided to supply and started collection of SDPs from registered and random repeat donors since January, 2000. METHODS: The utilization of platelets including SDPs was analyzed by mail survey from 33 hospitals and by statistical yearbooks of KRC, 2000. The necessity of SDPs and supplementary amounts of SDP in case of need was estimated. RESULTS: Total 483,611 units of platelets (692-80,414 units) and 12,150 units of SDP(0-3364 units) were utilized by 33 hospitals participated mail survey. The mean discard rate of platelets in the 33 hospitals was 1.5% (0%-15%). The total amounts of SDP collection in 19 hospitals among them were 10,031 units. About one third of 29 hospitals investigated, call for to use 100% of SDPs for patients. And most of the hospitals were cooperative using SDPs supplied from KRC. The amounts of SDP used in Big 5 hospitals, which is located in Seoul was 76.1% of total SDPs used in Korea. CONCLUSION: The relevant amount of supplied SDPs would be 80.000 unit/year, which is 50% of total supplied platelets by KRC. Efficient utilization of SDPs needs well organized collection, SDP stock control and supply system by regional groups of KRC blood center. In additionally, donor recruitment and maintenance for substantial supply of SDPs, and the supplementary support from the government is important.

A Comparison of the Software LDP Rev. C vs Rev. C2 in MCSR+ / 대한수혈학회지

BACKGROUND: It is necessary to protect patient from white blood cells (WBC) caused side effects of platelet transfusion by reducing the WBC contamination in single donor platelets (SDPs). Objective of the new software is to improve WBC depletion performance and collection efficiency. Revised software version, LDP Rev. C2 was installed in our MCSR+ (Hemonetics, USA). We compared the newly introduced software version with the previous software LDP Rev. C. METHOD: SDPs were collected from registered and random repeat donors who visited our blood center. After 49 single needle collections by MCSR+ (software LDP Rev. C) were performed, revised software (LDP Rev. C2) was installed and 48 single needle collections were carried out. The platelet count of donors were measured electronically. The target platelet yields were 3.0x10(11). All units of SDPs were tested for platelet yields and residual WBC. And other parameters were also evaluated. RESULTS: The MCSR+ LDP collected platelets with mean platelet yields of 3.3x10(11)(Rev. C) and 3.4x10(11)(Rev. C2). The total processing blood volume and collection time were significantly reduced in Rev. C2. The collection efficiency was also significantly improved in Rev. C2 (64% vs 57%). Residual WBC in all product collected from software Rev. C2 were below 1 106 and 71% of the products revealed residual WBC below 1 105, respectively. Citrate toxicity was not observed during the apheresis by Rev. C2. CONCLUSION: Revised software LDP Rev. C2 in MCSR+ showed improved collection efficiency and leukocyte depletion performance compared to the Rev. C. And optional control of citrate re-infusion rate seemed to reduce donor citrate reactions during the apheresis.