Sexual function according to infiltration of endometriosis of the rectovaginal septum: a cross-sectional study

SUMMARY OBJECTIVE: The aim of this study was to associate the degree of infiltration of rectovaginal septum endometriosis with dyspareunia and sexual function. METHODS: A cross-sectional study was carried out with 127 women followed up at a tertiary hospital from March 2021 to March 2022. The women's sociodemographic and clinical conditions and dyspareunia were evaluated. The sexual function was evaluated by the Female Sexual Function Index. RESULTS: A total of 53 women with type I, 37 with type II, and 37 with type III rectovaginal septum endometriosis were evaluated. The women had a mean age of 38.76±6.63 years and a mean body mass index of 27.62±5.11 kg/m2. The mean time of diagnosis of endometriosis was 6.94±4.98 years. On average, the study participants engaged in sexual activity/intercourse 1.88±1.25 times per week. There was no difference between the dyspareunia score (p=0.822) and sexual function (p=0.174) according to the types of rectovaginal septum endometriosis. Overall, 93.7% of the women with endometriosis had sexual dysfunction. There was no correlation between the degree of rectovaginal septum endometriosis infiltration with dyspareunia (r=0.05; p=0.55) or sexual function (r=0.07; p=0.39). CONCLUSION: Women with endometriosis have impaired sexual function, regardless of the degree of endometriosis infiltration.

Disfunções sexuais em mulheres jovens universitárias: estudo transversal / Sexual dysfunctions in young university women: a cross-sectional study

OBJETIVO: Verificar a frequência e os fatores associados à disfunção sexual em mulheres jovens universitárias. MÉTODOS: Trata-se de um estudo descritivo analítico de corte transversal. Participaram deste estudo 111 mulheres, estudantes, heterossexuais do curso de fisioterapia da Universidade Federal da Bahia. Cada participante respondeu a dois questionários autoaplicáveis "Investigação de fatores associados" e "Quociente sexual ­ versão feminina", entre os meses de setembro e outubro de 2019. RESULTADOS: Foi encontrado nesta população prevalência de 8% de disfunção sexual. O sintoma de esforço evacuatório esteve associado a pior desempenho/satisfação sexual pelo score total do QS-F (p=0,03), e quando avaliado por agrupamento de questões, foi encontrada associação entre esforço evacuatório e pior excitação (p=0,01), esforço evacuatório e mais dor (p=0,04); urgência urinária e mais dor (p=0,04); violência e pior excitação (p=0,05) e violência e menos satisfação/orgasmo (p=0,02). CONCLUSÃO: Os resultados sugerem que há baixa prevalência de disfunção sexual na população estudada, mas há associação entre sintomas de disfunções do assoalho pélvico e disfunções sexuais em mulheres jovens.

OBJECTIVE: To estimate the prevalence of sexual dysfunction in young college women. METHODS: This is a descriptive-analytical cross-sectional study. A total of 111 heterosexual women students of the physiotherapy course from the Universidade Federal da Bahia participated in this study. Each participant answered two self-administered questionnaires, "Investigation of associated factors" and "Sex ratio - female version" between September and October 2019. RESULTS: A prevalence of 8% of sexual dysfunction was found in this population. The symptom of evacuatory effort was associated with worse performance / sexual satisfaction by the total SQ-F score (p=0.03), and when assessed by a grouping of questions, an association was found between evacuatory effort and worse arousal (p=0.01), evacuatory effort, and pain (p=0.04); urinary urgency and pain (p=0.04); violence and arousal (p=0.05); and violence and less satisfaction/orgasm (p=0.02). CONCLUSION: The results suggest a low prevalence of sexual dysfunction in the studied population, but there is an association between symptoms of pelvic floor dysfunction and sexual dysfunction in young women.

Sexual health in Polish elderly men with coronary artery disease: Importance, expectations, and reality / 亚洲男科学杂志(英文版)

Deterioration in overall health, hormonal disturbances, and erectile dysfunction (ED) contributes to limitations in sexual activity in the elderly, which is further limited by incorrect beliefs about the hazards of sexual activity in cardiac patients. We aimed to analyze the occurrence of ED in elderly men, their perception of the relevance of good sexual function, and their expectations of physicians. A cross-sectional study encompassed 731 patients with coronary artery disease (CAD) subjected to cardiac rehabilitation. Demographic data and data on modifiable risk factors and patient expectations were collected. ED was assessed using the IIEF-5 questionnaire. Relationships among the risk factors for ED, occurrence of ED, and patient expectations, as well as the changes in the indicators between 2012 and 2016, were analyzed. The mean age of men was 70.7 ± 5.1 years. The prevalence of ED was 93.0%. The IIEF-5 score was significantly associated with age, tobacco smoking, exercise tolerance, time to diagnosis of CAD, and treatment with calcium channel blockers and diuretics. Patients declared that sexual activity was overall important (47.9%) or very important (25.6%). Three hundred and sixty (49.3%) patients expected their physician to show interest in their sexual health, but the topic was addressed in only 12.5%. Over the past few years, we have observed an increase in the awareness and importance of sexual health as well as a significant increase in patients' expectations of physicians to show interest in their sexual health. Patients' expectations of discussing and receiving treatment for ED remain an unmet medical need.

Influence of sexual function on the social relations and quality of life of women with premature ovarian insufficiency / Influência da função sexual nas relações sociais e na qualidade de vida de mulheres com insuficiência ovariana prematura

Abstract Objective To evaluate the impact of sexual function (SF) in the quality of life (QoL) of women with premature ovarian insufficiency (POI). Methods Case-control study in which 80women with POIwere evaluated using estrogen plus progestogen therapy, compared with 80 women matched by age (2 years) and presenting preserved gonadal function. Sexual function was evaluated using the Female Sexual Function Index (FSFI), and the QoL was evaluated using theWorld Health Organization's (WHO) QoL assessment instrument (WHOQoL-BREF). Results The mean age of the women with POI and of the control group was 38.4 ± 7.3 years and 38.1 ± 7.3 years respectively. The QoL, was worse among the POI group, and there were significant differences in the physical (63.4 ± 17.4 and 72.7 ± 15.2 respectively, p = 0.0004) and psychological (63.2 ± 14.6 and 69.3 ± 13.9 respectively, p = 0.0075) domains among this group when compared with the control group. Women with POI presented significantly lower arousal, lubrication, orgasm and satisfaction, more dyspareunia and a worse FSFI scores when compared with the control group. All aspects of SF correlate directly with the worsening of the QoL regarding social relationships. Conclusion Women with POI showed worse QoL and SF than the control group. The psychological aspects (desire, excitement, orgasm and sexual satisfaction) of SF had greater influence on the parameters of the QoL, while the physical aspects (pain and lubrication) had a low impact on the QoL. The poor SF in women with POI is directly correlated with a worsening acrossmultiple domains of the QoL; however, the negative impact is particularly important in the social domain. These results suggest that the improvement in sexuality can improve the social interactions of women with POI.

Resumo Objetivo Avaliar o impacto da função sexual na qualidade de vida (QV) de mulheres com insuficiência ovariana prematura (IOP). Métodos Estudo de caso-controle que avaliou 80 mulheres com IOP usando terapia hormonal combinada (progestagênio e estrogênio), em comparação com80mulheres com função gonadal preservada pareadas por idade (2 anos). A função sexual (FS) foi avaliada por meio do índice de função sexual feminina (IFSF) e a QV, por meio do instrumento da Organização Mundial de Saúde (OMS) para avaliação da QV (WHOQoLBREF, na sigla em inglês). Resultados Amédia etária dasmulheres comIOP e do grupo controle foi de 38,4 ± 7,3 e 38,1 ± 7,3 anos, respectivamente. A QV do grupo com IOP foi pior, e verificou-se uma diferença significativa nos domínios físico (63,4 ± 17,4 e 72,7 ± 15,2, respectivamente, p = 0,0004) e psicológico (63,2 ± 14,6 e 69,3 ± 13,9, respectivamente, p = 0,0075) para asmulheres comIOP quando comparadas como grupo de controle.Mulheres comIOP apresentaram pior pontuação para excitação, lubrificação, orgasmo, satisfação, dispareunia, e pior índice de FS emcomparação ao grupo controle. A piora em todos os aspectos da FS foi diretamente correlacionada com a piora no domínio das relações sociais da QV. Conclusão Mulheres comIOP apresentaram pior QV e FS do que o grupo controle. Os aspectos psicológicos (desejo, excitação, orgasmo e satisfação sexual) da FS exerceram grande influência na QV, enquanto os físicos (dor e lubrificação) exerceram pouca influência. A má função sexual em mulheres com IOP está diretamente correlacionada com uma piora em vários domínios da QV; porém, o impacto negativo é particularmente importante no domínio social, sugerindo que a melhora da sexualidade pode auxiliar na melhor integração social das mulheres com IOP.

Eurycoma Longifolia as a potential adoptogen of male sexual health: a systematic review on clinical studies / 中国天然药物

Eurycoma longifolia (EL) has been well recognized as a booster of male sexual health. Over the past few decades, numerous in vivo animal studies and human clinical trials have been conducted across the globe to explore the promising role of EL in managing various male sexual disorders, which include erectile dysfunction, male infertility, low libido, and downregulated testosterone levels. The aim of the present review is to analyze and summarize the literature on human clinical trials which revealed the clinical significance and therapeutic feasibility of EL in improving male sexual health. This systematic review is focused on the following databases: Medline, Wiley Online Library, BioMed Central, Hindawi, Web of Knowledge, PubMed Central and Google Scholar, using search terms such as "Eurycoma longifolia", "EL", "Tongkat Ali", "male sexual health", "sexual infertility", "erectile dysfunction", "male libido", and "testosterone levels". Notably, only human clinical studies published between 2000 and 2014 were selected and thoroughly reviewed for relevant citations. Out of 150 articles, 11 met the inclusion criteria. The majority of articles included were randomized placebo-controlled trials, multiple cohort studies, or pilot trials. All these studies demonstrated considerable effects of EL on male sexual health disorders. Among them, 7 studies revealed remarkable association between the use of EL and the efficacy in the treatment of male sexual disorders, and remaining 4 studies failed to demonstrate sufficient effects on male sexual health. In summary, there is convincing evidence for the prominence of EL in improving the male sexual health. The review also substantiates the use of current methodology in the development of novel and more rationale natural herbal medicines for the management of male sexual disorders.

Flibanserin- A Novel drug for Hypoactive Sexual Desire Disorder

Low sexual desire is a very common symptom in women of any age with potential negative consequences on quality of life and well-being according to The American Psychiatric Association’s Diagnostic, Statistical Manual of Mental Disorders (DSM-IV TR) and the World Health Organization’s International Classifications of Disease. They also established that the definition of hypoactive sexual desire disorder (HSDD) should include not only the lack or absence of sexual fantasies or desire for any form of sexual activity, but also the presence of personal distress and/or interpersonal difficulties. Flibanserin, a novel, non-hormonal, multifunctional serotonin agonist antagonist (MSAA) was used in most of the pre-menopausal women diagnosed with Hypoactive Sexual Desire Disorder (HSDD) but its approval also faced a little scepticism.

Prevalence and Predictive Factors of Sexual Dysfunction in Iranian Women: Univariate and Multivariate Logistic Regression Analyses / 가정의학회지

BACKGROUND: Female sexual dysfunction, which can occur during any stage of a normal sexual activity, is a serious condition for individuals and couples. The present study aimed to determine the prevalence and predictive factors of female sexual dysfunction in women referred to health centers in Ilam, the Western Iran, in 2014. METHODS: In the present cross-sectional study, 444 women who attended health centers in Ilam were enrolled from May to September 2014. Participants were selected according to the simple random sampling method. Univariate and multivariate logistic regression analyses were used to predict the risk factors of female sexual dysfunction. Diffe rences with an alpha error of 0.05 were regarded as statistically significant. RESULTS: Overall, 75.9% of the study population exhibited sexual dysfunction. Univariate logistic regression analysis demonstrated that there was a significant association between female sexual dysfunction and age, menarche age, gravidity, parity, and education (P<0.05). Multivariate logistic regression analysis indicated that, menarche age (odds ratio, 1.26), education level (odds ratio, 1.71), and gravida (odds ratio, 1.59) were independent predictive variables for female sexual dysfunction. CONCLUSION: The majority of Iranian women suffer from sexual dysfunction. A lack of awareness of Iranian women's sexual pleasure and formal training on sexual function and its influencing factors, such as menarche age, gravida, and level of education, may lead to a high prevalence of female sexual dysfunction.

Expressões da sexualidade feminina no transtorno de personalidade borderline / Female sexuality expression in Borderline Personality Disorder

O transtorno da personalidade borderline (TPB) consiste num padrão de funcionamento instável nas relações interpessoais, autoimagem, afetos e impulsividade, que traz sofrimento ao indivíduo e prejuízos à sua sexualidade. Este estudo teve como objetivo descrever como é a vida sexual de pacientes com diagnóstico de TPB. Trata-se de uma pesquisa qualitativa e, como instrumento, utilizou-se uma entrevista semiestruturada. Participaram do estudo sete mulheres com diagnóstico de TPB. A coleta de dados foi realizada a partir da análise de conteúdo de Bardin. Observou-se que algumas participantes não se sentem à vontade em manter relações sexuais com os seus parceiros, sofreram abuso sexual na infância, manifestam a presença de parafilias e/ou sentem dificuldade em alcançar o orgasmo. Concluiu-se que as pacientes com TPB apresentam dificuldades na esfera sexual, o que deve ser observado e avaliado pelo profissional de saúde mental.

The borderline personality disorder (BPD) consists of a pattern of unstable operation in interpersonal relationships, self-image, affections and impulsivity, which causes suffering to the individual and their sexuality. This study aimed to describe how the sexual life of patients diagnosed with BPD. It is a qualitative research and as an instrument a semi-structured interview was used. Seven woman who had a diagnosis of BPD took port in the study seven women who had a diagnosis of BPD. Data collection was performed from the Bardin content analysis. We observed that some participants did not feel comfortable in having sexual relations with their partners, have suffered childhood sexual abuse, reveal paraphilias and have difficulty achieving an orgasm. It was concluded that patients with BPD present difficulties in the sexual sphere, which must be observed and evaluated by mental health professional.

Frecuencia de disfunción sexual en un grupo de pacientes diabéticas mexicanas / Frequency of sexual dysfunction in a group of Mexican diabetic patients

Introducción: la diabetes mellitus es el trastorno endocrino más frecuente en el mundo. Las complicaciones crónicas de esta enfermedad como la retinopatía, nefropatía y neuropatía tienen origen en los efectos vasculares, sin embargo existen otras complicaciones menos evidentes como las que ocurren a nivel de la función sexual.Objetivo: identificar si existe una mayor frecuencia de disfunción sexual en pacientes portadoras de diabetes mellitus tipo 2 en comparación con pacientes no diabéticas.Métodos: se realizó un estudio de casos y controles en la Unidad de Medicina Familiar "Marina Nacional" de la Ciudad de México. Fueron seleccionadas 32 pacientes portadoras de Diabetes Mellitus tipo 2 de 35 a 50 años de edad con más de dos años de evolución de la enfermedad. El grupo control se integró con 32 pacientes que acudieron a la misma unidad médica por otras causas diferentes a enfermedades crónicas, con el mismo rango de edad. A ambos grupos se les aplicó el cuestionario de autoevaluación estandarizado Arizona Sexual Experience Scale, posteriormente se correlacionó el grado de control metabólico y el tiempo de evolución de la enfermedad con la presencia de disfunción sexual.Resultados: se identificó mayor presencia de disfunción sexual en las pacientes portadoras de diabetes mellitus que en pacientes no diabéticas. No encontramos evidencia de asociación entre disfunción sexual y tiempo de evolución de la diabetes, así como tampoco entre disfunción sexual y control metabólico.Conclusiones: la disfunción sexual femenina se presentó con mayor frecuencia en mujeres diabéticas

Background: diabetes Mellitus is the most frequent endocrine disorder in the world. The chronic complications of this disease such as retinopathy, nephropathy and neuropathy originated from vascular effects although there are other less evident complications as the ones that occur at the sexual function level.Objective: to identify if there is a higher frequency of sexual dysfunction in patients who suffer from Type 2 diabetes mellitus as compared with non diabetic patients.Methods: we performed a case study and a control to the "Marina Nacional" Family Medicine Unit in Mexico City. We selected 32 patients suffering from Type 2 diabetes mellitus aged 35 - 50 years who had history of more than two years´ evolution of the disease. The control group was composed of 32 patients of the same age that presented to the same medical unit complaining of other health problems different from chronic diseases. Both groups were applied the same standardized self-assessment questionnaire Arizona Sexual Experience Scale (ASEX). Later, the degree of metabolic control and the time of evolution of the disease with sexual dysfunction were correlated.Results: it was identified that the presence of sexual dysfunction in patients suffering from diabetes mellitus was higher than in non diabetic patients. We found no evidence of the association between sexual dysfunction and the time of evolution of diabetes or between sexual dysfunction and metabolic control.Conclusions: female sexual dysfunction was more frequent in diabetic women

Association of Sexual Disorders with Peripheral Neuropathy in Alcohol Dependence

The alcoholic neuropathies developed in approximately 34% of chronic alcoholics and the sexual dysfunction had been experienced in 8-54% of male alcoholics(Schiavi 1990). The aims of this study were to identify the prevalence of subclinical polyneuropathies and sexual disorders in alcohol dependence, and to evaluate the association between them. The nerve conduction velocity(NCY), electromyography(EMG), and pudendal somatosensory evoked potentials(SEPs were tested for the male alcoholics(N=34) and controls(N=17 for NCV & EMG, N=25 for pudendal SEPs). The pudendal SEPs were measured by the following procedures, in which we simulated the dorsal nerve of penis attached by the ring electrode(stimulus intensity, three times of threshold ; stimulus rate, 1-4.7Hz: stimulus duration, 0.1 or 0.2msec), and recorded at the scalp(active electrode, 2cm behind Cz ; reference electrode, Fz. The NCV and EMG detected signs of peripheral neuropathies in 79.4% of alcoholics. Among the alcoholics, 64.7% were abnormal on the pudendal SEPs. Among the alcoholics who revealed abnormality on EMG and NCV, 81.4% were abnormal on the pudendal SEPs, in which 51.9% were not responded. The P1 latencies between peripheral neuropathies and sexual disorders in the alcoholic. The prevalence of subclinical neuropathies and sexual disorders seemed to be much higher in alcohol dependence that expectation, and these two problems were relatively correlated, and our results suggested that the peripheral polyneuropathies were one of the prerequisites of sexual disorders.