Application of multimodal neuroendoscopy combined with microsurgery in the surgical treatment of cystic and solid brain tumors / 中国医师进修杂志

Objective To investigate the value of multi-modal neuroendoscopy combined with microscopy in the treatment of solid cystic brain tumors. Methods Fifty patients with cystic solid tumors admitted to Wuzhou Worker′s Hospital(the Seventh Affiliated Hospital of Guangxi Medical University) from February 2016 to February 2019 were enrolled. The patients were divided into two groups by random number table method. The patients in control group (25 cases) received microsurgery, and the patients in observation group (25 cases) received microsurgery combined with neuroendoscopy. All patients underwent CT or MRI. The differences in tumor resection rate between the two groups were observed and compared. The postoperative complications and Glasgow Outcome Scale (GOS) scores were compared between the two groups. All patients were followed up for 12 months after surgery. The tumor recurrence rate and mortality rate of the two groups were compared. Results The total resection rate of the tumor in observation group was 80.00%(20/25), and in control group was 48.00%(12/25), and there was significant difference (P<0.05). The postoperative GOS score of observation group was higher than that of control group: (4.52 ± 1.73) scores vs. (3.65 ± 1.15) scores, t=2.094, P=0.041. The incidence of postoperative complications, tumor recurrence rate and the mortality rate between two groups had no significant difference (P>0.05). Conclusions Multi-modal neuroendoscopy combined with microscopy can significantly improve the total resection rate of cystic brain tumors and improve the prognosis without increasing the risk of surgery.

Diagnosis and Treatment for 44 Cases of Posterior Fossa Hemangioblastoma / 中国医师杂志

Objective To investigate the diagnosis and treatment of posterior fossa hemangioblastoma.Methods The data of 44 cases with posterior fossa hemangioblastoma verified by surgery and pathology were analyzed retrospectively.Results Preoperative definite diagnosis cases were 41.Total tumor removal was achieved in 37 cases. Four cases died of the operation.Conclusions Posterior fossa solid hemangioblastoma are still challenging neoplasmas.For this kind of tumor,biopsy and partial removal are forbidden,and this tumor is removed after devascularity of supply blood artery.CT and MRI are major preoperatively diagnosis method for posterior fossa hemangioblastoma. The application of special microsurgical technique can improve surgical efficacy.