RESUMO
Arterial spin labeling (ASL) technology is a popular technique for evaluating and studying cerebral perfusion in recent years. It can sensitively detect the abnormal cerebral perfusion and effectively avoid the potential risks caused by exogenous contrast agents in other tests. Detection of the abnormal cerebral blood flow perfusion by ASL technology can early predict cognitive decline in normal elderly, explore the pathogeneses of mild cognitive dysfunction and Alzheimer's disease, and evaluate the cerebral blood flow around the ischemic focus and the establishment of collateral circulation in patients with aphasia after stroke. At the same time, it is verified that the decrease of cerebral blood flow perfusion is another precipitating factor of primary progressive aphasia except cortex atrophy. Although there are still some limitations, the ASL technology has a good prospect in the application of cognitive disorders.
RESUMO
A growing number of clinical studies have shown that arterial spin labeling (ASL) magnetic resonance imaging has its unique value in the diagnosis and treatment of dementia. This article reviews the application principles and imaging manifestations of ASL in patients with different types of cognitive impairment, such as vascular cognitive impairment and Alzheimer's disease.