A Single Centre Experience of Spontaneous Bacterial Peritonitis in Ascites with Cirrhosis : A Record Based Observational Study

Spontaneous Bacterial Peritonitis (SBP) is one of the complicated infections in patients with cirrhosis and ascites which can be fatal if not diagnosed and treated. This is a record based observational study using the data of all patients admitted with established cirrhosis of liver with ascites. Aim of the study was to find out the incidence of SBP in cirrhosis patients and also to study the clinical profile of SBP. Thirty nine patients’ data were included in the study. Three patients had classic SBP, one patient had Culture Negative Neutrocytic Ascites (CNNA) and two had bacterascites. Patients were treated with injection cefotaxime (2 gm) 8hourly for 5 days and clinical and laboratory parameters were evaluated.

Post-traumatic primary bacterial peritonitis / 대한법의학회지

Spontaneous bacterial peritonitis (SBP) is a bacterial infection of ascites arising from liver cirrhosis, nephrotic syndrome and so on. Primary bacterial peritonitis (PBP) is a rare intraabdomial infection in the absence of underlying diseases or rupture of the viscus. The authors report an autopsy case of posttraumatic primary bacterial peritonitis in the otherwise physically healthy young female. She was beaten repeatedly around the abdomen with human physical instruments for a prolonged time.

Changes of Serum Endotoximia and Interleukin-6 Levels Before and After Treatment at Intestine Depollution and Adjustment Intestine Microenvironment in Patients With Liver Cirrhosis / 中国医师杂志

Objective To observe the changes of serum endotoxin and interleukin-6 level before and after treatment at intestine get rid of filth and adjustment intestine microenviroment in patients with advanced stage liver cirrhosis and to oberserve the incidence of spontaneous bacterial peritonitis(SBP) and to research a method that can more efficient reduce the incidence of SBP.Methods Group A was given conventional treatment such as protection liver,supplement human albumin and uragogue;goup B was given FPA 0 2g tid po,continuous three days on the basis of two weeks conventional treatment,group C was given Tab comfort get 0 5g tid po,Changtai orally taken liquid,10ml tid po,lactulose 10ml tid po, for all 8 weeks,on the basis of group B treatment after pausing use FPA.Results Serum endotoxin and interleukin-6 levels in group A was not significantly changes after treatment,,SBP incidence was higher than both group B and group C;at group B,serum endotoxin and interleukin-6 levels decline,SBP incidence significantly drop afer treatment,at group C,serum endotoxin,interleukin-6 level and SBP incidence significantly drop,the difference was significant at statistics as compared with group A and B.Conclusions The treatment at intestine get rid of filth and adjustment intestine microenviroment can effectively reduce serum endotoxin and interleukin-6 levels and can significantly reduce the incidence of SBP.