Analysis of the Clinical Characteristics of Cutaneous Malignant Tumors: 11-year Single-center Study in Daejeon City and Chungnam Province / 대한피부과학회지

BACKGROUND: The occurrence of cutaneous malignant tumors has been increasing worldwide due to changes in various environmental factors. OBJECTIVE: Our study aimed to analyze the overall tendency of clinical characteristics in single-center patients with cutaneous malignant tumors according to sex, age, duration, size, anatomic site, treatment, and concomitant diseases. METHODS: We retrospectively reviewed the medical records and clinical photographs of 319 patients diagnosed with cutaneous malignant tumors (basal cell carcinoma, squamous cell carcinoma, melanoma, lymphoma, Paget's disease, metastatic skin cancer, mycosis fungoides, angiosarcoma, dermatofibrosarcoma protuberans, Kaposi sarcoma, malignant fibrous histiocytoma, Merkel cell carcinoma) and 109 patients diagnosed with premalignant tumors (Bowen's disease) between January 2007 and January 2017. RESULTS: The average annual incidence of malignant cutaneous tumors was 2.4%. In total, 158 males (36.9%) and 270 females (63.1%) were included with a mean age of onset of 66 years. Among the malignant tumors, basal cell carcinoma (30.8%) was the most common, while the incidences of squamous cell carcinoma (18.9%), melanoma (6.3%), and lymphoma (4.4%) were also high. The predominantly involved anatomic sites were the face (67.3%), trunk (11.5%), and legs (10.9%). Most cases involved solitarily existing tumors (77.3%), and pruritus (21.7%) was the most common accompanying symptom. Among the 69.6% of patients who received treatment for their tumors, the most common method was surgical removal. No significant increase in concomitant diseases or environmental factors was detected. CONCLUSION: Our study is meaningful as an overall and recent review of various types of cutaneous malignancies that provides preliminary data for further large-scale nationwide studies.

A Statistical Study of Dermatoses in Kangwon Province, 2010~2014 / 대한피부과학회지

BACKGROUND: The prevalence of skin diseases at a university hospital may not truly indicate their prevalence in the general population; nevertheless, it is the only available source of information. OBJECTIVE: This study aimed to investigate the prevalence of common dermatoses and compare this with previous reports. METHODS: We reviewed 29,477 new outpatients who visited the department of dermatology at Wonju Severance Christian Hospital from 2010 to 2014, and statistically analyzed the findings. RESULTS: Among the 29,477 outpatients, 14,501 (49.2%) were men and 14,976 (50.8%) were women. More patients were in their sixth decade (17.1%) or over 70 years (15.4%), in their seventh decade (13.5%) or in their fifth decade (13.0%), comprising 59% of the total outpatients. The 20 most common dermatoses were found to be urticaria, dermatophytosis, allergic contact dermatitis, other types of eczema, atopic dermatitis, pruritus, verruca, herpes zoster, alopecia, psoriasis, seborrheic dermatitis, drug eruptions, folliculitis, rosacea, benign epidermal tumor, melanocyte nevus, vitiligo, scabies, herpes simplex virus infection, and bacterial infection. In the distribution of dermatoses as disease groups, viral disease (11.2%), atopic dermatitis and eczema (10.7%); contact dermatitis and drug eruption (10.3%); erythema and urticaria (8.4%); fungal disease (7.6%); skin appendage disease (6.9%); seborrheic dermatitis, psoriasis, and pustular dermatoses (5.5%); epidermal nevi, neoplasms, and cysts (4.8%); pruritus and neurocutaneous dermatoses (4.6%); and acne (3.8%) constituted 73.8% of the total. CONCLUSION: Compared to the previous studies in the same area, the distribution of skin diseases was similar. The increasing tendency of older individuals with diseases in Gangwon province has persisted since 2000.

Clinical Observation of Cutaneous Malignant Tumors and Premalignant Lesions in North-western Gyeonggido Province over 8 Years (2005~2012): A Single Center Study / 대한피부과학회지

BACKGROUND: The incidence of cutaneous malignant tumors and premalignant lesions has continuously increased worldwide. OBJECTIVE: The purpose of this study was to analyze recent changes in the incidence and clinical characteristics of precancerous lesions and cutaneous malignant tumors in North-western Gyeonggido Province and to compare them with other previously reported data. METHODS: We reviewed 107 cases of premalignant lesions and 218 cases of cutaneous malignant tumors out of a total 38,926 new outpatients who had visited the Department of Dermatology at the Ilsan Paik Hospital from January 2005 to December 2012. RESULTS: The average annual incidence of premalignant lesions among the total number of new outpatients was 0.27% and that of cutaneous malignant tumors was 0.56%. The annual incidence of premalignant lesions increased by an average of 1.136 times per year, and that of cutaneous malignant tumors increased by an average of 1.038 times per year for 8 years. The most common premalignant lesion was actinic keratosis (74.77%). Among cutaneous malignant tumors, basal cell carcinoma (42.64%), squamous cell carcinoma (21.32%) and malignant melanoma (8.63%) were common. The mean age of onset was 74.04 years in precancerous lesions and 67.00 years in cutaneous malignant tumors. The most common site for cutaneous malignant tumors was the face (52.75%). The nose (29.57%) was the most preferential site on the face. CONCLUSION: The incidence of premalignant lesions and cutaneous malignant tumors has continuously increased in North-western Gyeonggido Province. Over half of the cases of cutaneous malignancies involved the head and neck area in our studies. Dermatologists need to be aware of clinical presentations of cutaneous malignancies on the head and neck.

A Statistical Study of Dermatoses in Wonju (2005~2009) / 대한피부과학회지

BACKGROUND: While the incidence of skin diseases in our university hospital may not indicate their true incidence in the population, it nonetheless represents the only available source of information. Recently, the composition of the Wonju population has changed rapidly in that the population of old people is increasing and urbanization is accelerating. Thus, statistical study of the latest data is necessary. OBJECTIVE: To study the prevalence of common dermatoses and compare this with previous reports. METHODS: We reviewed 27,718 new outpatients who visited the department of dermatology at Wonju Christian Hospital from 2005 to 2009, and statistically analyzed the findings. RESULTS: The study results are summarized as follows: Of the 27,718 outpatients, the total number of male patients was 14,190 (51.2%), and the numbers of female patients was 13,528 (48.8%). The most frequent age groups were the fifth decade (15.9%), sixth decade (13.9%), seventh decade (13.2%), and fourth decade (12.5). The 20 most common dermatoses were dermatophytosis, urticaria, atopic dermatitis, allergic contact dermatitis, other eczema, verruca, alopecia, herpes zoster, pruritus, psoriasis, drug eruption, vitiligo, acne, seborrheic dermatitis, folliculitis, benign epidermal tumors, nevocellular nevus, irritant contact dermatitis, bacterial diseases, and rosacea. The dermatoses which revealed a decreasing tendency to be treated by medicine included dermatophytosis, atopic dermatitis, other eczema, pruritus, psoriasis, drug eruption, vitiligo, acne, and irritant contact dermatitis. An increasing tendency was noted in urticaria, allergic contact dermatitis, verruca, alopecia, herpes zoster, seborrheic dermatitis, folliculitis, benign epidermal tumor and nevocellular nevus. Diseases with high seasonal distribution in summer were dermatophytosis, herpes zoster, vitiligo, folliculitis, irritant contact dermatitis and bacterial infections. However, atopic dermatitis, pruritus, and psoriasis showed high incidence in the winter period. Verruca, acne and nevocellular nevus had a peak incidence in both summer and winter. CONCLUSION: The distinct characteristic of skin diseases of the Gangwon province was a high incidence of pruritus and seborrheic dermatitis which represent the senile diseases.

A Statistical Study of Cutaneous Malignant Tumors (2001~2005) / 대한피부과학회지

BACKGROUND: The incidence of skin cancers has been continuously increasing worldwide. OBJECTIVE: Our purpose was to analyze the recent changes and clinical characteristics of cutaneous premalignant lesions and malignant tumors, and to compare those with other previously reported data. METHODS: We reviewed clinical data and histopathology reports from 125 cases of cutaneous premalignant lesions and 261 cases of malignant tumors out of a total of 23,971 new outpatients who had visited the Department of Dermatology at the Seoul National Hospital during a 5 year period (2001~2005). RESULTS: The incidence of cutaneous premalignant lesions was 0.52% and that of malignant tumors was 1.08%. The most common cutaneous premalignant lesion was actinic keratosis (72%). Among the malignant tumors, basal cell carcinoma (42.1%) was the most common, followed in order by squamous cell carcinoma (19.5%), malignant melanoma (10.7%), metastatic carcinoma (9.9%) and lymphoma (9.1%). The incidence of basal cell carcinoma was markedly increased compared to research results that had been done in the past for the same hospital. CONCLUSION: The incidence of skin cancers has been continuously increasing, and it is mostly due to the increasing incidence of basal cell carcinoma.

A Statistical Study of Outpatients During the ten Years From 1981 to 1990 / 대한피부과학회지

BACKGROUND: The incidence of skin diseases in the university hospital cannot be a true indication of their prevalence in the population, but it offers the only available source of information on the their ecology. OBJECTIVE AND METHODS: To study the prevalence of common dermatoses and compare these to previous reports, we reviewed 67,924 new outpatients who visited the dermatology clinic at Hanyang University Hospital in Seoul from Jan. 1st, 1981 to Dec. 31st, 1990. RESULTS: The results of the study are summarized as follows : 1. Among the 67,924 outpatients, the number of male patients was 32,812(48.4%) and female patients 35,112(51.6%). 2. Age distribution of patients were 17,883(26.3%) in the 3rd decade, 13,319(19.6%) in the 1st decade, 11,678(17.2%) in the 4th decade, 9,884(14.6%) in the 2nd decade in order. 3. The distribution of dermatoses as disease groups were eczema(23.9%), urticaria-drug erup-tion(13.2%), skin appendage disorder(12.9%), dermatophytosis(11.1%), viral infection(7.7%), disease due to animal parasi es(5.7%), and bacterial infection(3.8% ). 4. The 15 most common dermatoses were dermatophytosis(10.1%), contact dermatitis(8.8%), urticaria(7.8%), acne vulgaris(6.6%), other eczemas(65%), atopic dermatitis(5.0%), bacterial infections(3.8%), scabies(3.7%), seborrheic dermatitis(3.6%), drug eruptions(2.9%), verruca(2.1%), herpes zoster(1.9%), psoriasis(1.7%), syphilis(1.5%), and vitiligo(1.4%), 5. Those dermatoses which showed an annually increasing tendency were acne vulgaris, urticaria, contact dermatitis, seborrheic dermatitis, and those of decreasing tendency were scabies, bacterial infections, syphilis, and vitiligo. 6. Dermatophytosis, urt caria, bacterial infection, seborrheic dermatitis, verruca, and vitiligo occurred frequently during the summer. The incidence of other eczemas, scabies, atopic dermatitis, and her pes zoster increased during the winter, 7. In sexual distribution, dermatophytosis, scabies, seborrheic dermatitis were more frequent in the males, whereas contact dermatitis, urticaria, other eczemas, acne vulgaris, and herpes zoster were more frequent in the females. 8. In age distribution, atopic dermatitis and bacterial infections were the most frequent in the 1st decade. Acne vulgans, syphilis, psoriasis, verruca, and dermatophytosis were the most frequent in the 3rd decade, with scabies and vitiligo in the 2nd decade, and herpes zoster in the 7th decade. CONCLUSION: The distribution of skin diseases in our hospital showed similar with reported studies in other areas. Comparing these results with an Bang's report 10 year ago in Seoul, there was relative high incidence of viral infections compared to the low incidence of bacterial infections.

Statistical Study on Congenital Heart Disease

A Statistical observations were done on 587 pediatric patients who were diagnosed as having congenital heart disease by cardiac catheterization angiography and operation at Dong San Hospital Keimyung University, during the period of January 1982 to june 1987. The results were as follows 1) Out of 587 patients, 317 cases were male and 276 cases were female. There were female preponderance in atrial septal defect and patent ductus arteriosus, whille in male tetralogy of Fallot, pulmonary stenosis, and ventricular septal defect. 2) The incidence of congenital heart disease were as folliws;ventricular septal defect 35.7% tetralogy of Fallot 17.5%, patient ductus arteriousus 13.9%, arterial septal defect 7.5% and pulmonary stenosis 2.9%. 3) Most of the patients were visited hospital for the first time between the age of 2 and 10 years. 4) Assosiated anomalies of major congenital heart disease were as follows:the most commonly associated anomaly in ventricular septal defect were pulmonary stenosis and patent ductus arteriosus. Pulmonary stenosis was frequently associated with atrial septal defect. Right sided aortic arch and pentalogy were assosiated with tetralogy of Fallot. The mitral regurgitation was associated with patent ductus arteriosus mostly. 5) The overall surgical mortality was 6.8%. The mortality was high in tetralogy of Fallot(16.1%), transposition of great vessels(28.5%).

Statistical Study of Femoral Neck Fractures in Korea: Review of 30 articles reported on Journal of Korean Orthopaedic Association / 대한정형외과학회잡지

The fracture of femoral neck, the unsolved fracture, is a msjor periphersl fracture of our skeleton, and for more than century its treatment and the results hsve been a matter of controversy and inquiry among surgeons, and although the results obtained today show improvement, they are not at all comparsble to those of other fractures. This study was performed to find the characteristics of femoral neck fractures in Korea and to give the direction of further treatment. Through the review of 30 articles reported on Journal of K.O.A., we suggest the followings are essential for further study. l. Epidemiologic study of femorsl neck fractures based on statistical data needs to be performed. 2. The study should be directed not only the frscture itself but also the prevention of the fracture via the study of osteoporosis. 3. The relationship of severity of fracture, time frorn trauma to treatment, and the result of treatment established by our own data is to be established.

A Statistical Study of Dermatoses in Wonju Area During the Recent 5 Years ( 1980 ~ 1984 ) / 대한피부과학회지

In this report, 20,536 new outpatients who have visited the Department of Dermatology of Wonju Christian Hospital from Jan. 1st, 1980 to Dec. 31st, 1984 were analized. The results suggest that the age, sex, monthly and yearly distribution patterns of dermatoses in Wonju area are similar to those of other areas in Korea except that infective dermtoses(40.3%), especially scabies(9.8%) and herpes zoster(1.6%) are more common.

A Statistical Study of Bullous Skin Diseases During Last 20 Years ( 1966 ~ 1985 ) / 대한피부과학회지

This study was done to observe the statistical difference on bullous skin disease patients (pemphigus, bullous pemphigoid, dermatitis herpetiformis, epidermolysis bullosa) who visited the department of dermatology, Kyungpook National University Hospital,from January 1966 to Deceniber 1985, For those 24 cases which tested positive under direct immunofluorescent (DIF) testing, agreement percentage of histopathologic diagnosis was compared. The results were summarized as follows : 1) 51 of 45,091 new outpatients (0.113%) were bullous skin disease patients. 2) By sex, age and monthly distribution, there was no significant difference, though epidermolysis bullosa was seen for the most part in those under 10 years of age. 3) By individual disease distribution, the pemphigus cases numbered 8, of which most cases were within the 30~60 year age group. Bullous pemphigoid cases numbered 14, of which most cases were over 50 years of age. Female patients were 2.5 times more common than male patients. Dermatitis herpetiformis cases numbered 20, and were relatively diminished in recent years. The peak age group was the 3rd decade. Epidermolysis bullosa numbered 9 cases. 4) The compatibility of the histopathologic diagnosis to the DIF diagnosis in 24 DIF positive cases indicated that of DIF positive pemphigus the histopathologic diagnrsis agreed with the DIF diagnosis in 75%, of bullous pemphigoid, 58% and of dermatitis herpetiformis, 50%.

A Statistical Study of Morgolian Spot / 대한피부과학회지

This survey was made on 1462 cases in different age groups, from the neonate to the age of 15, to analyse the data statistically concerning the prevalence, size, shape, site and color of Mongolian spot. The results were as follows: 1) Of 1462 cases, Mongolian spot(s) was(were) present in 759(51. 9%) with the sex ratio of male to female, 1: l. 2. The prevalence could be divided into 3 stages, high(neonate to 3years), abruptly declined(4 to 9year), steadily declined (10 to 15years) 2) The mean and standard deviation of diameter represented 4. 56+2. 96cm(M +SD), ranging from 0. 5 to 21 cm. 3) The two most common shapes were ovoid(45. 5%,) and irregularly circular (31.4%). 4) The two most common sites were sacrococcygeal(80. 1%,) and gluteal(75. 1%). 5) The two most common colors were blue(75. 1 %) and purple-blue(13. 5%).

A Statistical Study of Pediatric Dermatoses During Last 10 Years (1975 ~ 1984) / 대한피부과학회지

11,609 of childhood new outpatients seen in Department of Dermatology of Seoul National University Hospital from 1975 to 1984 were analyzed statistica,lly. The study results were summarized as follows: l. 11, 609 out of 48, 188 new outpatients were under 15 years old age, amounting to 24. l %. 2. The 10 most common dermatoses were atopic dermatitis, vitiligo, urticari, hemangiorna, contact dermatitis, fungal disease, molluscum contagiosum, scabies, impetigo and nevocellular neuvs. The most freguent age groups were 2 to 6 years amounting to 47 2p, af total outpatients. 4. The peak incidence occurred in August, while the lowest incidence occurred in November and October. 5. Dermatoses which showed increasing tendency were nevocellular nevus and vitiligo, those of decreasing tendency were contact dermatitis and impetigo,

The Statistical Study on Acute Drug and Chemicals Intoxication in Children

A statistical study on 135 cases of acute poisoning who were treated in Pediatric department of Soon Chun Hyang College Hospital from May, 1974 to August, 1980 was performed. The results are as follows: 1. Seasonal incidence was more prevalent in summer. (from June to August, Table 2) 2. It occurred more frequently in male than female and high incidence was noted in 1 to 3 year-old age group(Table 5). 3. The causative chemicals were found to be 58 kinds & the commonest chemical was insecticides which were 16.3% of all cases. Rodenticides and tranquilizers(11.9%), D.D.S. (5.1%), kerosence(3.7%) were the next common causatvie agents. And drugs were more frequent than non-drug agents(Table. 3). 4. Accidental poisoning was more frequent than therapeutic and suididal purpose(Table 6). 5. It occurred most frequently during 3 to 6 O'lock in the afternoon and especially from 6 to 9 O'lock in morning and in the evening in the 0 to 1 year-old age. 6. There were complications which were aspiration pneumonia(3 cases). Corrosive pharyngitis (1 cases) and anoxic brain damage(1 cases) respectively. And death occurred in 1 cases due to insecticide.