Clinical observation on the effect ofKangyan-Yihao prescription on facial steroid-dependent dermatitis / 国际中医中药杂志

Objective To study the clinical effect ofKangyan-Yihao on facial steroid-dependent dermatitis.Methods 63 patients of steroid-dependent dermatitis in ShuGuang Hospital Affiliated to Shanghai University of TCM were recruited and randomly divided into a treatment group with 32 patients and a control group with 31 patients. Patients in both groups were forbidden to use hormone treatment and taken cetirizine 10 mg orally every night. On this basis, the treatment group was treated withKangyan-Yihao prescription and the control group was treated withTianQing-Fuxin. The total curative effects, itching-reliving degree and life quality were compared between the two groups after the treatment after two weeks.Results After the treatment, the EASI score, DLQI score skin itching score in the treatment group(2.41±2.64, 4.93±2.90, 1.07±0.83, respectively) were better than those in the control group(2.52±2.73,5.07±3.59, 1.30±0.65,P<0.01 orP<0.05).ConclusionsKangyan-Yihao has a significant effect in treating facial steroid-dependent dermatitis, specially for the oily and pustule lesions.

Clinical research of autohemotherapy combined with bacillus calmette-guerin polysaccharide and nucleic acid in treatment of facial steroid-dependent dermatitis / 中国医师进修杂志

Objective To observe the clinical effect and security of autohemotherapy combined with bacillus calmette-guerin polysaccharide and nucleic acid in treatment of facial steroid-dependent dermatitis.Methods The 74 patients with facial steroid-dependent dermatitis were divided into treatment group (38patients) and control group (36 patients) according to the treatment method.The patients in treatment group were treated with autohemotherapy combined with bacillus calmette-gnerin polysaccharide and nucleic acid 1 ml muscle injection,every 3 days a time for 4 weeks.The patients in control group were treated with bacillus calmette-guerin polysaccharide and nucleic acid,every 3 days a time for 4 weeks.The effect was compared between the two groups.Results The total effective rate in treatment group was 84.2％(32/38),in control group was 63.9％(23/36),there was significant difference between the two groups (P ＜ 0.05).No serious adverse reaction was found in two groups.Conclusion Autohemotherapy combined with bacillus calmettegnerin polysaccharide and nucleic acid is safe and effective in treatment of facial steroid-dependent dermatitis.