Parallel Study of Medodhara Kala and Abdominal Adipose Tissue with Special Reference to Sthoulya (Obesity)

Obesity which is neuroendocrine disorder seems to be common predisposing factor for almost all non-communicable diseases. This neuroendocrine disturbance causes multiple systemic disorders and finally Ayurhasa (reduction in longevity of life) by various means. Ayurveda mentioned eight pathophysiological conditions considered as Nindya (worse conditions). Atisthool (excessive weight) is one of these conditions due to improper Aahara (dietary habits), Vihar (sedentary life style) and changed sleep pattern. Apachita meda (improperly metabolized fat) deposited in Udara (abdomen). Medodharakala according to Ayurveda and abdominal linings bear several similar characteristics related to fat and Medodhatu deposition. Deterioration of functioning of Medodhara kala leads to deposition of Apachita meda leading to Sthoulya. In obesity, abdominal wall, space between organs stores much amount of adipose tissue (site of Meda deposition). So this article reveals with parallel study of Medodhara kala and abdominal adipose tissue to find out similarity.

Effect of Shuddha Guggulu on Metabolic Syndrome - A Case Report

Metabolic syndrome is conglomeration of symptoms composed of impaired fasting glucose, abdominal obesity, hypertension and dyslipidemia. It is associated with cardio metabolic risk factors with increased risk of multiple chronic diseases, including cancer and cardiovascular disease because of the increased amount of visceral fat together with a chronic inflammatory state. Metabolic Syndrome is resulted by the causative factors which are Santarpanakaraka in nature leading to Medodushti, which in turn leads to Medoroga. The Santarpana karaka Nidanas include the food articles that are rich in Snigdhamsha, Madhura rasa, Guru and Pichchila gunas. By consuming the food rich in such qualities produces the Rasa dhatu which is excessively composed of the qualities like Ati Snehamsha and Madhuratara Guna which produces excess Medo dhatu and causes Sthoulya. Ama present in the Medodhatu leads to further Medo dushti and manifests Metabolic Syndrome. Shuddha Guggulu is potent Ama pachaka dravya and does Pachana of the circulating Atisnigdha Ama in the form of lipoproteins. And also Guggulu having Lekhaneeya Guna reduces deposition of Medo dhatu and prevents inflammatory process by its anti- inflammatory potential. Aim: To assess the effect of Shuddha Guggulu in Metabolic Syndrome, dyslipidaemia. Methodology: Oral administration of the preparation in the patient. Result: There was marked improvement in signs, symptoms and biochemical parameters after intervention. Conclusion: Shuddha Guggulu is significantly effective in reducing lipid levels and CRP

A Clinical and Laboratory Profile of Sthaulya W.S.R to Obesity and its Management by Amritadya Guggulu

In Ayurveda, it is regarded as Medoroga which includes fat tissue and fat metabolism, results from the excessive accumulation of Meda (fat/ adipose tissue) and Mamsa (flesh/ muscle tissue) leading to flabbiness of hips, abdomen, and breast. It is considered as Santarpanottha Vikara and counted one among the Ashtnindita Purusha by Ayurvedic Acharayas. According to Ayurveda, Sthoulya begins with an imbalance of Doshas (Vata, Pitta and Kapha), Agni (digestive fire), Malas (waste products) or an imbalance of Srotas (microcirculatory channels). This collection of imbalances then interferes with the formation of tissues or Dhatus and leads to a tissue imbalance that we experience as Sthoulya. It is most prevailing condition being faced by majority of the population, but yet among the most neglected health problem in the world. In this regard approach of this study is to give safer, comprehensive and rational option for treating Sthaulya (Obesity) and this is a humble attempt to probe into the different pathophysiological aspects behind Sthaulya, taking into consideration the classical therapy coupled with modern interpretations. Amritadya Guggulu by the virtue of its Rasapanchaka (Rasa- Katu, Tikta, Kashaya, Guna- Laghu, Ruksha and Virya- Ushna, Vipaka- Katu, Dosha Karma- Kapha Vatashamaka) is effective in the management of Sthoulya including all Kapha predominant pathologies, leading to Samprapti Vigatana of Sthoulya. Hence this study is carried out to establish the efficacy of the treatment considering the clinical and laboratory profile of obesity (Sthoulya). The study was done on 30 patients taken from both IPD & OPD of RGGPG Ayurvedic College and Hospital, Paprola, H.P. The duration of the trial was 60 days with follow up of 15 days and the observations obtained are analyzed statistically after the end of the study.

Effects of medicated enema and nasal drops using Triphaladi oil in the management of obesity - A pilot study

An open label, randomized, comparative, interventional pilot study was done to assess the effect of Lekhana Basti (medicated enema) and Rechana Nasya Karma (Errhine therapy) in the management of Sthoulya with special reference to obesity. In the study 30 clinically diagnosed patient of either sex were randomly divided into two groups. In Basti group, Lekhana Basti in Karma Basti manner was given for 30 days. Anuvasana Basti (enema with Triphaladi Taila) in the dose of 120 mL and Asthapana Basti (enema with Triphaladi decoction etc.) in the dose of approximately 960 mL was given. In Nasya group, Rechananasya on alternate days was given with Triphaladi (oil) in the dose of 0.5 mL per nostril for total 28 days. The patients were assessed on objective criteria such as such as weight, chest circumference, mid-arm circumference, mid-thigh circumference, triceps skin fold thickness, sub-scapular skin fold thickness, abdominal skin fold thickness, waist-hip ratio and lipid profile. It was observed that Basti group was a better intervention in providing relief, however there intergroup standard deviation was low on most of the variable expect the lipid profile. The results suggest that the Nasya Karma may be developed as a better practical approach in obesity management.

A Comparative Clinical Study To Evaluvate The Effect Of Haridradi Gana Churna And Triphala Churna Udvartana In Sthoulya (obesity)

In the present century due to the busy and sedentary life people open the gate to welcome numerous diseases. Sthoulya is one among the major diseases that falls under the category of Santarpanottha vyadhi. The term overweight and obesity refers to body weight that is greater than what is considered healthy for a certain height. Sthoulya is mainly caused by Kapha, Vata Doshas and Meda Dhatu. Udvartana has better results in the management of Sthoulya, as it does Kapha-Vatahara, Medo vilayana. So, the present has been conducted to compare and evaluate the effect of Haridradi gana Churna and Triphala Churna Udvartana in Sthoulya. The study has been conducted in two groups with 20 patients each. One with Haridradi gana Churna and other group with Triphala Churna which are Kapha-Medahara & Kapha-Pramehahara respectively because of Laghu, Ruksha & Ushna properties. The present study concludes saying Haridradi gana Churna showed better results than Triphala Churna.

Mode Of Action Of “amritadya Guggulu” In The Management Of Sthoulya W.s.r To Obesity

Obesity (Sthoulya) is the major and basic cause of lifestyle disorders like Diabetes mellitus (T2DM), Coronary heart disease (CHD), Hypertension. Obesity (Sthaulya) is increasing at an alarming rate in developed industrialized countries which are undergoing rapid nutrition and lifestyle transition. Obesity is one of the most effective diseases which affect someone’s social, physical and mental status. In Ayurveda, Sthoulya (Obesity) is regarded as Medoroga, a disorder of Meda Dhatu, which includes fat tissue and fat metabolism. According to Ayurveda, Sthoulya begins with an imbalance of Doshas (Vata, Pitta and Kapha), Agni (digestive fire), Malas (waste products) or an imbalance of Srotas (microcirculatory channels). This collection of imbalances then interferes with the formation of tissues or Dhatus and leads to a tissue imbalance that we experience as excess weight. Overweight and obesity are linked to more deaths worldwide than underweight. Overall, about 13% of the world adult population (11% of men and 15% of women) was obese in 2016. The worldwide prevalence of obesity nearly tripled between 1975 and 2016. Amritadya Guggulu possesses Rasa- Katu, Tikta, Kashaya, Guna- Laghu, Ruksha and Virya- Ushna, Vipaka- Katu, Dosha Karma- Kapha Vatashamaka is effective in the management of Sthoulya. By virtue of its Rasapanchaka, contents of drug are very well indicated in Kapha predominant pathologies. Due to this property, it breaks the Samprapti of Sthoulya. Hence the present attempt is done to encompass the up to date comprehensive literature to study the mode of action of Amritadya Guggulu in the management of Sthoulya w.s.r. to Ayurvedic properties and modern pharmacology.