Evaluation and correlation of stress scores with blood pressure, endogenous cortisol levels, and homocysteine levels in patients with central serous chorioretinopathy and comparison with age‑matched controls.

Context: Stress had been associated with the development of central serous chorioretinopathy (CSC). The study was designed to evaluate the effect of stress on other risk factors of CSC such as serum cortisol levels, serum homocysteine levels, and blood pressure (BP) in CSC patients. Aims: To compare stress scores, serum cortisol and serum homocysteine levels, and BP of CSC patients with that of control population and to correlate stress scores of CSC patients with BP, serum cortisol levels, and serum homocysteine levels. Materials and Methods: Stress scores, serum morning and evening cortisol levels, serum homocysteine levels, systolic and diastolic BP of 54 CSC patients were measured and compared with that of 54 age‑ and sex‑related controls using Student’s t‑test. Stress scores of CSC patients were correlated with systolic and diastolic BP, serum morning and evening cortisol levels and serum homocysteine levels and Pearson correlation coefficient (r) were calculated. Results: Stress scores, serum homocysteine levels, serum morning and evening cortisol levels, and systolic and diastolic BP were all elevated in CSC patients as compared with age‑ and sex‑related controls (P < 0.05). Stress scores of CSC patients were found to correlate strongly with serum homocysteine levels, serum morning and evening cortisol levels, and systolic and diastolic BP, with r values 0.82, 0.8, 0.8, 0.8, and 0.81, respectively (P < 0.0001). Conclusions: Stress scores were elevated in CSC patients and were strongly correlated with serum homocysteine and cortisol levels and BP.

Evaluation of Stress in Professional Life and Other Factors Among Young Technology Professionals in South India.

Stress has been a topic of interest in the last century, since its description by Hans Selye. Stressors could be anything from the daily life, professional or domestic, eventually leading the deleterious health outcomes. However some types of stressors were believed to be necessary for growth, which were termed eustress. In the present study we evaluated the stress levels in software professionals (n=155) from Karnataka State, India by using Professional Life stress Score (PLSS) and Perceived Stress Score (PSS) after explaining the subjects about the questionnaire and response types and obtaining their informed consent. Ethical clearance was obtained from the institutional ethics committee before the beginning of the data collection. Apart from the responses for the questionnaire, their BMI was calculated by carefully measuring their height and weight. Their other demographic data such as age, matrimonial status were also collected. From the results we found that PLSS score was elevated to mild and moderate degree among the study group, which was not correlated with either their age or matrimonial status. However in contrast, the PSS scores were elevated to higher degree and it was well correlated with BMI, age and number of years of experience. From the results we found that these young technical professionals of Bangalore and Mangalore did not have much professional stress but they were influenced by other factors which produce overall stress as evidenced by the elevated PSS scores. Thus we herestate that this study produced results which was helpful in differentiating the professional life environment causing stress and other compounding factors influencing the psychological well being. We, therefore conclude that well employed young professional enjoy their work but other extraneous factors could lead to stress.

Lung Uptake of 99mTc-sestamibi during Routine Gated Exercise SPECT Imaging: Comparison with Left Ventricular Ejection Fraction and Severity of Perfusion Defect / 대한핵의학회잡지

BACKGROUND: Lung-to-heart uptake ratio (LHR) in (201) Tl-chloride myocardial perfusion scan is believed to be a reliable marker for left ventricular (LV) dysfunction, but the clinical value of LHR is controversial for 99mTc-MIBI imaging. Furthermore, most of results suggesting lung uptake of 99mTc-MIBI as a potential marker for LV dysfunction used immediate post-stress images, instead of routine images acquired 1 hour after tracer injection. The goal of our study was to investigate whether LHR evaluated with routine gated 99mTc-MIBI imaging can reflect the degree of perfusion defect or left ventricular performance. SUBJECTS AND METHODS: 241 patients underwent exercise 99mTc-MIBI myocardial SPECT were classified into normal myocardial perfusion (NP, n=135) and abnormal myocardial perfusion (AP, n=106) group according to the presence of perfusion defect. LHR was calculated from anterior projection image taken at 1-hour after injection. Two regions of interest (ROIs) were placed on left lung above LV and on myocardium showing the highest radioactivity. Subjects were classified by left ventricular ejection fraction (LVEF), as Gr-I: > 50%, Gr-II: 36-50%, Gr-III: 13, LHR was compared among these groups. RESULTS: In NP group (n=135), LHR, were higher in men than women (men: 0.311+/-0.03, women: 0.296+/-0.03, p or = 0.38, women> or = 0.37) of the LHR of the subject with normal perfusion. Increased LHR were observed more frequently in subjects with lower LVEF (Gr-I: 11.1%, Gr-II: 27.0%, Gr-III: 36.4%, p< 0.05) and higher SSS (Gr-A: 14.0%, Gr-B: 6.7%, Gr-C: 18.2%, Gr-D: 40.7%, p< 0.05). CONCLUSIONS: LHRs obtained from routine 99mTc-MIBI gated SPECT images were weakly correlated with LVEF and perfusion defect. Although significant overlaps were observed between normal and abnormal perfusion group, LHRs could be used as an indirect marker of severe perfusion defect or reduced left ventricular function.

Stress Relating Factors of Working Women in a Bank / 대한산업의학회지

We surveyed 343 female bank clerks to find out associations between stress and a variety of factors including general, menstruation and reproductive characteristics of the participants. Unmarried women composed the majority of younger, lower income and lower education groups than married did. They also showed higher. though not significantly higher, scores for psychosocial well being index(PWJ) and the first three items of the stress survey. And married women scored slightly higher only in the fourth item of the stress survey. Among the subgroups of married and unmarried women, many factors contributed to a higher stress score in two or more items of the stress survey; in unmarried women, lower education level, little physical exercise, and large family inhabitants, in contrast married women, higher monthly income and greater working hours were related to higher stress scores. According to the menstruation factors, subgroups with dysmenorrhea or irregular cycle and scanty bleedig volume in unmarried women and subgroups with dysmenorrhea in married women showed higher stress scores in PWI. In married women, the proportion of those who have been pregnant was 77.2% and the proportion of those who have experienced spontaneous abortion was 24.1%. Those who have ever experienced two or more spontaneous abortion showed higher, though not statistically significantly higher. scores for PWI. In conclusion, dysmenorrhea was associated with high stress score in two groups. And the other factors related to higher score of PWJ were different between unmarred and married women, which should be considered in a management plan for mental health promotion.