Una inusual causa de estrechez de la vía aérea laringotraqueal / An unusual cause of laryngotracheal airway narrowing

La enfermedad relacionada con inmunoglobulina (Ig) G4 es una enfermedad de reciente conocimiento que puede comprometer cualquier órgano teniendo preferencias por ciertas regiones del cuerpo, donde la región de cabeza y cuello es uno de sus principales puntos afectados, pudiendo comprometer tanto la órbita, glándulas salivales, glándulas lagrimales, glándula tiroides, cavidades paranasales, hueso temporal, faringe y laringe. Este último órgano es infrecuentemente comprometido, solo existiendo 12 casos registrados en la literatura antes de la publicación de este escrito. Presentamos un caso de una mujer de 49 años con historia de disnea frente a esfuerzo, diagnosticándose una estenosis subglótica la cual fue manejada quirúrgicamente con una reconstrucción laringotraqueal. En el estudio histopatológico se evidenció histología compatible con enfermedad relacionada con IgG4, por lo que se inició tratamiento médico con corticotera- pia oral por un lapso de 2 meses en conjunto con inmunología. Paciente luego de 4 años de seguimiento, no ha presentado recaídas, manteniendo un lumen subglótico adecuado.

Immunoglobulin (Ig) G4-related disease is a medical condition of recent knowledge that can compromise any organ, having preferences for certain regions of the body, where the head and neck region is one of the main affected points, being able to affect orbit, salivary glands, lacrimal glands, thyroid gland, paranasal cavities, temporal bone, pharynx and larynx. The latter is infrequently compromised, with only 12 cases registered in the literature before the publication of this writing. We present a case of a 49-year-old woman with a history of exertional dyspnea, diagnosed with a sub- glottic stenosis which was managed surgically with laryngotracheal reconstruction. The histopathological study revealed histology compatible with IgG4-related disease, so medical treatment with oral corticosteroid therapy was started for a period of 2 months in conjunction with immunology. After 4 years of follow-up, the patient has not presented relapses, maintaining an adequate subglottic lumen.

Ectopic thymic tissue in subglottis of children: evaluation and management

Abstract Objectives: Ectopic thymic tissue in the subglottis is an extremely rare disease that causes airway obstruction. Few cases reported were accurately diagnosed before surgery. Methods: A case of a 2-year-old boy with airway obstruction caused by a left subglottic mass was reported. The presentation of radiological imaging, direct laryngoscopy and bronchoscopy, pathology, and surgical management were reviewed. An extensive search in PubMed, EMBASE, Web of Science, Google Scholar, and EBSCO of English literature was performed without a limit of time. Results: Besides our case, only six cases were reported since 1987. The definitive diagnosis on these patients were made with the findings of pathology, of which, five were ectopic thymus and two were ectopic thymic cysts. Our case was the only one with a correct suspicion preoper-atively. Four cases underwent open surgical resection, and two cases underwent microlaryngeal surgery, while one deceased after emergency tracheostomy. No recurrences were found by six patients during the follow-up after successful treatments. Conclusion: Ectopic thymus is a rare condition, infrequently considered in the differential diagnosis of subglottic masses. Modified laryngofissure may be an effective approach to removing the subglottic ectopic thymus and reconstructing the intact subglottic mucosa.

Lesiones laringotraqueales por ahorcamiento fallido / Laryngotracheal lesions by near-hanging

Introducción: La lesión por ahorcamiento se inscribe dentro del traumatismo cerrado de la tráquea cervical. Objetivo: Presentar seis enfermos tratados por secuelas de un intento fallido de ahorcamiento y revisión la literatura sobre los métodos diagnósticos y terapéuticos. Métodos: Se realizó un estudio descriptivo de seis pacientes tratados entre 1989 y 2011 en el Hospital "Hermanos Ameijeiras". Todos fueron remitidos de diferentes hospitales, con una traqueostomía para el control de la vía respiratoria. Las variables estudiadas fueron: sexo, edad, diagnóstico definitivo, técnicas quirúrgicas empleadas, evolución posoperatoria, complicaciones y mortalidad. Resultados: Todos los pacientes fueron del sexo masculino, con edad entre 16 y 66 años (mediana 28,5). Cuatro tenían menos de 30 años, uno 38 y el último 66. El diagnóstico se hizo mediante traqueoscopia flexible y tomografía axial computarizada. La lesión se localizó en subglotis (2) y tráquea (4). Dos pacientes fueron operados antes de la remisión: resección traqueal (1) y laringotraqueal (1). El tratamiento definitivo, en nuestro centro, consistió en resección traqueal (4) y subglótica (2). No se presentaron complicaciones ni fallecidos. Durante el seguimiento postoperatorio (7 a 26 meses), cinco lesionados tuvieron resultados excelentes y uno satisfactorio, asociado con voz débil. Conclusiones: El traumatismo traqueal por ahorcamiento fallido es muy raro. El tratamiento oportuno y adecuado puede reducir las complicaciones y la mortalidad. Un equipo quirúrgico con experiencia puede lograr resultados satisfactorios en un grupo importante de lesionados. La traqueostomía, con anestesia local, es el método de elección para controlar la VR en pacientes con traumatismo cervical(AU)

Introduction: The hanging injury is considered a closed trauma of the cervical trachea. Objective: To present the cases of six patients treated for sequelae after failed hanging attempt, and to review the literature about diagnostic and therapeutic methods. Methods: A descriptive study was carried out of six consecutive patients treated between 1989 and 2011 at Hermanos Ameijeiras Hospital. All were referred from different hospitals, with a tracheostomy for controlling the airway. The variables studied were sex, age, definitive diagnosis, surgical techniques used, postoperative evolution, complications and mortality. Results: All patients were male, aged between 16 and 66 years (median: 28.5). Four were less than 30 years old; one, 38; and the last, 66. The diagnosis was made by flexible tracheoscopy and computerized axial tomography. The injury was located in the subglottis (2) and the trachea (4). Two patients were operated on before referral, through tracheal (1) and laryngotracheal (1) resection. Definitive treatment in our center consisted of tracheal (4) and subglottic (2) resection. There were no complications or deaths. During the postoperative follow-up (7-26 months), five injured patients had excellent outcomes and one had satisfactory outcomes, associated with a weak voice. Conclusions: Tracheal trauma after failed hanging is very rare. Timely and appropriate managment can reduce complications and mortality. An experienced surgical team can achieve satisfactory outcomes in a large group of injured people. Tracheostomy, under local anesthesia, is the method of choice for controlling the airways in patients with cervical trauma(AU)

Clinicopathological Study of Rhinosporidiosis: A Study of 20 Cases in Government ENT Hospital, Hyderabad, Telangana – A Tertiary Care Center

Background: Rhinosporidiosis is a chronic granulomatous disease caused by Rhinosporidium seeberi which was once believed to be a sporozoan and then was included in phycomycetes, and now included under Mesomycetozoa. It is one of the common tropical diseases, most commonly affecting the mucosa of upper respiratory tract, chiefly the nose and nasopharynx. Other sites such as conjunctiva, lacrimal glands and subcutaneous tissue may also get infected. It presents as polypoidal mass. Aim and objective: To study incidence, age and gender distribution and clinicopathological features of Rhinosporidiosis. Materials and methods: A retrospective study of 20 cases was undertaken over a period of 5 years (July 2012 to June 2017) in the Department of Pathology, Government ENT Hospital, Hyderabad. The resected tissue specimens were subjected to routine processing, cutting; staining and histopathological features were studied with Hematoxylin and Eosin stain. Results: Nasal cavity was most commonly involved site, excepting in one case, where sub-glottis was involved. Males were predominantly affected i.e. 17 (85%) cases, whereas 3 (15%) cases were reported in females. Age range was between 8-70 years. (Both of them were males). N. Sreemani Kumari, Madhavi Parigi, Seema Afroze. Clinicopathological Study of Rhinosporidiosis: A Study of 20 Cases in Government ENT Hospital, Hyderabad, Telangana - A Tertiary Care Center. IAIM, 2017; 4(8): 103-107. Page 104 Conclusion: Rhinosporidiosis most commonly presents as polypoidal mass in the nasal cavity and may also present at extra-nasal sites. Histopathology is the standard method for confirmation of diagnosis

Estenosis laringotraqueal: experiencia clínica / Laryngo-tracheal stenosis: our experience

Introducción: La estenosis laringotraqueal es una patología de difícil manejo y obtener un resultado que permita, al sujeto que la padece, volver a tener una función adecuada fonorrespiratoria y deglutoria, no siempre es factible de obtener. Objetivo: Presentar una serie clínica de pacientes que tienen una estenosis de la vía aérea superior (VAS) y que fueron intervenidos quirúrgicamente. Como objetivo secundario es evaluar si a técnicas similares hay o no diferencias entre los grupos etarios. Material y método: Presentamos un análisis retrospectivo de los pacientes intervenidos quirúrgicamente por los autores. En él se realiza la descripción demográfica de los casos, sitio de la estenosis, tipo de intervención según edad; porcentaje de éxito en la decanulación después de una o varias intervenciones, necesidad de reoperación, tipo de injerto y tutores utilizados. Se dividió el grupo en pediátrico (hasta los 18 años) y adulto (mayores de 19 años). Los resultados fueron analizados con las pruebas no paramétricas de x² y de Fisher. Resultados: La casuística consta de 88 pacientes intervenidos quirúrgicamente para reparar una estenosis laringotraqueal. Los menores de 18 años corresponden a 45 casos (51 por ciento). El porcentaje de éxito alcanzado en la primera cirugía es de 75,6 por ciento (34/45 casos) en los menores de 18 años y de 76,7 por ciento por ciento (33/43 casos) en los mayores de 19 años. Se reoperan 15/21 casos fracasados en primera instancia; logrando decanular a 13 de ellos aumentando el éxito a 90,9° por ciento. Fracasan a las reoperaciones y pendientes de resolver aún, 8 casos. La técnica más utilizada fue la reconstrucción laringotraqueal con injerto de cartílago costal ya sea anterior y/o posterior, por ser la estenosis subglótica el sitio de la lesión. El porcentaje de éxito para esta técnica es de 68,3 por ciento; siendo en los menores de...

Introduction: Laryngo-tracheal stenosis is a condition difficult to manage and obtain results which permit the person who suffers it recover phonorespiratory and deglutory function. This is not always possible to achieve. Aim: Present a clinical series of patients with stenosis of the VAS and underwent surgery. A secondary objective is to assess whether or not there are similar technical differences between age groups. Material and method: We present a retrospective analysis of patients surgically treated by the authors. They present demographic description cases, site of stenosis, type of intervention according to age; percentage of successful decannulation after one or more interventions; reoperation, type of graft and stents used. The group was divided into pediatric and adult. Statistical analysis was performed with x2 and Fisher. Results: The case mix consists of 88 patients who underwent surgery to repair laryngo-tracheal stenosis. Children under 18 years correspond to 45 cases (51 percent percent). The percentage of success in the first surgery is 75.6 percent percent (34/45 cases) in children under 18 and 76.7 percent percent (33/43 cases) over 19years. 15/21 failed cases were reoperated in the first instance; 13 of them were decannulated increasing success to 90.9 percent percent. Reoperation failure and still unresolved, 8 cases. Surgical technique used was laryngotracheal reconstruction with costal cartilage graft either anterior or posterior being subglottic the site of stenosis. Success rate to this technique is 68.3 percent percent. In patients under 18 years old is 71 percent percent success and over 18 years 60 percent percent. For tracheal stenosis, tracheal resection with end to end anastomosis has a success rate of over 90 percent and it is performed mostly in the age group over 18 years...

The Treatment Outcomes of Primary Subglottic Cancer / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Primary subglottic cancer is uncommon, so our understanding of primary subglottic cancer is limited. The purpose of this study is to review the clinical characteristics and treatment result of primary subglottic cancer from our experience. SUBJECTS AND METHOD: During the period from Nov. 1996 to Nov. 2010, patients with primary subglottic cancer were reviewed retrospectively. The mean follow up period was 46.1+/-40.9 months. We analyzed its clinical characteristics, stage, treatment results and survival rate. RESULTS: Of 824 patients with diagnosed laryngeal cancer, 8 (0.97%) had primary subglottic cancer and hoarseness (50.0%) is the most common initial presenting symptom. The symptom of dyspnea was found in 25.0% (2/8) of the patients and squamous cell carcinoma in 75% (6/8). At the time of diagnosis, the four clinical stages of TNM, T1, T2, T3 and T4, had 1 (12.5%), 2 (25.0%), 1 (12.5%) and 4 (50.0%) patients, respectively. There were two cases of cervical lymph node metastases, N1 and N2c. No distant metastasis was found. Two groups of patients comprising of two patients each received surgery alone or radiation alone as an initial treatment; another two groups of patients comprising of two patients each received concurrent chemoradiation or surgery plus radiation therapy alone. The overall 2-year survival rate was 80.0% and 2-year disease free survival rate was 51.7% in patients with squamous cell carcinoma. CONCLUSION: Despite the infrequency of primary subglottic cancer, it is important to understand its clinical characteristics and treatment results during the early diagnosis to make the prognosis better.

A Case of Adenoid Cystic Carcinoma on Subglottis / 대한이비인후과학회지

Adenoid cystic carcinoma (ACC) is a rare malignant tumor. Its incidence is less than 1 percent of all head and neck malignancies and approximately 10 percent of all salivary neoplasms. There are no clear guidelines for the treatment of ACC, but a combination of surgery and postoperative radiotherapy has been usually recommended. Subglottic cancer has a lower incidence than does laryngeal cancer, whose incidence is in the range of 4 to 6 percent of all cancers of the larynx. Because of the rarity of this tumor in the larynx, no series has been large enough to permit statistical evaluation of treatment. We report a case of adenoid cystic carcinoma on subglottis, which was treated with surgical excision and postoperative radiotherapy. The relevant literature is briefly reviewed.

Sub Glottic Schwannoma of the Larynx

Schwannomas are rare neurogenic tumors. Their laryngeal location is uncommon.We present a case of subglottic schwannoma which is very rare.