RESUMO
Objective To evaluate the renal peripheral inflow perfusion in patients with liver cirrhosis by region of interest ( ROI) quantification of color Doppler technique . Methods Fifty-eight patients with cirrhosis with normal renal function were selected as the case group ,and classified into A grade ( 10 cases) , B grade (23 cases) and C grade ( 25 cases) according to Child-Pugh classification criteria . Thirty healthy volunteers were selected as the control group .Resistance index ( RI) of interlobar artery and interlobular artery were measured in all groups . The blood flow of renal cortical was analyzed using ROI quantification in the corresponding region ,and vascular index ( VI) ,flow index ( FI) ,vascularization flow index ( VFI) were obtained . Results ① Patients of B grade group and C grade group in the cirrhosis group showed sparser corical blood flow and slender blood vessels . ②No statistical difference were found in the resistance index of the renal interlobaries and interlobular arteries between A grade group and control group ( P ＞0 .05) ,the RI of renal interlobar arteries and interlobular arteries in B grade group and C grade group were significantly higher ( P ＜0 .01) . Compared with the A grade group ,the RI of renal interlobar arteries and interlobular arteries in B grade group and C grade group increased evidently ( P ＜ 0 .01).The RI of renal interlobar arteries and intralobular arteries between B grade groupand C grade group showed no statistical difference (P＞0 .05).③Compared with the control group ,the VI ,FI ,and VFI of A ,B ,and C grade groups declined obviously ( P ＜ 0 .05).With the increase of cirrhosis grade ,VI ,FI and VFI gradually decreased ,and the difference among the three groups were statistically significant ( P ＜ 0 .05 ).Conclusions Patients with cirrhosis have showed a reduction in renal peripheral vascular bed and blood perfusion earlier than laboratory tests for renal dysfunction .ROI quantification of Color Doppler technique can sensitively assess changes of early renal peripheral blood perfusion in patients with cirrhosis .