RESUMO
OBJECTIVE: To investigate the situation of the key quality parameters of the main domestic and imported tetanus-based combined vaccines used in the basic immunization phase in our country. METHODS: The quality parameters of 50 batches of vaccine products which were manufactured respectively by domestic and foreign manufacturers were analyzed and compared. RESULTS: AND CONCLUSION: Domestic and imported tetanus-based combined vaccine products have different advantages and the quality and these products may be improved further in some respects. It is suggested that more domestic and foreign vaccine manufacturers improve the product quality based on the characteristics of their own products to provide safer and more effective vaccines that can also more convenient for use in the future.