Adaptação transcultural para a língua portuguesa da Avaliação Cognitiva Dinâmica de Terapia Ocupacional para Crianças (DOTCA-Ch) / Cross-cultural adaptation into portuguese of the Dynamic Occupational Therapy Cognitive Assessment for Children (DOTCA-Ch)

[{"text": "Introdução: A Avaliação Cognitiva Dinâmica de Terapia Ocupacional para crianças (DOTCA-Ch) é um\r\ninstrumento de avaliação específico para terapeutas ocupacionais (TO), que avalia o desempenho cognitivo de crianças com idade de 6 a 12 anos, em 22 subtestes dinâmicos distribuídos em cinco áreas cognitivas: Orientação, Percepção Espacial, Práxis, Construção Visuomotora e Operações de Pensamento. Objetivo: Apresentar o processo de adaptação transcultural da Bateria DOTCA-Ch para a língua portuguesa. Método: A Bateria DOTCA-Ch foi traduzida e adaptada segundo uma metodologia rigorosa, a partir da tradução, retrotradução, avaliação das equivalências Conceitual, Cultural, Idiomática e Semântica feita por um Comitê de Especialistas e aplicação do pré-teste. Resultados: A Bateria DOTCA-Ch foi traduzida, adaptada para o português brasileiro, retrotraduzida e a versão final foi encaminhada para um Comitê de Especialistas, a fim de avaliar as equivalências (375 itens), considerando a população-alvo e o contexto cultural do Brasil. Nos itens referentes à avaliação das equivalências Conceitual e Cultural, a concordância entre os examinadores foi de 100%, e na avaliação das equivalências Idiomática e Semântica, a média foi de 95,2%. Na fase do pré-teste, esta versão foi aplicada em 9 crianças saudáveis da cidade de Santos. Conclusão: A Bateria DOTCA-Ch mostrou-se aplicável às crianças saudáveis, entretanto, tendo em vista as especificidades desse grupo populacional, tornaram-se necessárias adaptações em relação ao tempo de aplicação da bateria. Observou-se que as crianças se beneficiam do uso das mediações, visto que isto contribuiu para uma considerável melhora de seu desempenho durante a execução das tarefas.", "_i": "pt"}, {"text": "Introduction: The DOTCA-Ch Battery (Dynamic Occupational Therapy Cognitive Assessment for\r\nChildren) is a specific assessment tool for occupational therapists (O.T.). The battery evaluates the cognitive performance of 6- to 12-year-old children, from 22 dynamic subtests distributed in five cognitive areas: Orientation, Spatial Perception, Praxis, Visuomotor Construction and Thinking Operations. Objective: To demonstrate how the cross-cultural adaptation process of the DOTCA-Ch Battery into Portuguese took place. Method: The DOTCA-Ch Battery was translated and adapted according to a rigorous methodology that proposes the translation, back-translation, and Conceptual, Cultural, Idiomatic and Semantic equivalence evaluation by a committee of experts and through a following pre-test. Results: The DOTCA-Ch Battery was translated and adapted for Brazilian Portuguese and back-translated to the original language. After that, a committee of five experts evaluated 375 items in order to assess the equivalences, taking into consideration the target population and the cultural context of Brazil. In the pre-test phase, this version was applied to 09 healthy children of the city of Santos. Conclusion: The DOTCA-Ch battery is feasible to be used with healthy children. However, some adjustments related to the time of application are necessary in the case of this specific population group. It was observed that children benefit from the use of mediation, as this considerably improved their performance during the execution of tasks.", "_i": "en"}]

The study of cognitive function and synaptic plasticity in depressed rats following electroconvulsive shock / 中国神经精神疾病杂志

Objective To investigate the role of autophagy and synaptophysin (SYP) in cognitive impairment in de?pressed rats receiving electroconvulsive shock (ECS). Methods Clean and healthy adult male Sprague-Dawley rats were acclimatized to a standard laboratory environment for 7 days. The chronic unpredictable mild stress (CUMS) was used to establish the rat model of depression. Behavior tests were conducted before and after CUMS to evaluate the depression and cognition level of rats. After establishment of the model, 24 rats were randomly divided into ESC group (group E) and depression group (group D) with 12 rats in each group. The rats in group E were administered 80 mg/kg of propofol (10 mg/mL) by intraperitoneal injection, followed by ECS treatment. The rats in group D were administered propofol by intra?peritoneal injection, followed by sham-ECS treatments. The above interventions were conducted daily for 7 consecutive days. After the interventions, rats underwent behavior tests as before. Subsequently, rats were killed and specimens were collected for measurements. Immunohistochemistry was performed to examine autophagy markers such as Beclin 1 and LC3Ⅱand ELISA was used to detect SYP in the hippocampus. Results Group E after ECS significantly increased the percentage of sucrose preference (68.2%±8.7%), rearing times (7.0±1.9), total horizontal distance [(569.5±70.0) cm], es? cape latency [(21.9±5.3)s] and space exploration time [(20.5±3.9)s] compared with group D or group E before ECS. There was no significant difference in these index between groups before ECS or in group E between before and after ECS(P>0.05). Compared with group D, group E had upregulated protein expression levels of Beclin 1 and LC3Ⅱin CA1, CA3, DG as well as the area near the hippocampus and increased SYP contents (P<0.05). Conclusions Cognitive impairment in depression rats following ECS correlates with activated autophagy and increased SYP by ECS.

Effect of Scalp Acupuncture Combined with Cognitive Training on Cognitive Function of Acute Stroke Patients / 中国康复理论与实践

@#Objective To observe the effect of scalp acupuncture combined with cognitive training on the cognitive function of stroke patients in the acute stage. Methods 68 stroke patients with cognitive disorder were divided into the treatment group (n=34) and the control group (n=34). All patients of two groups were treated with routine therapy and cognitive rehabilitation training by professional physiotherapists, but the treatment group were added with scalp acupuncture. They were regularly evaluated with Loewenstein Occupational Therapy Cognition Assessment (LOTCA) before and 2 months after treatment. Results The scores of LOTCA significantly improved in the two groups after treatment (P<0.05), and improvement of the treatment group was better than those of the control group（P<0.05）. Conclusion The scalp acupuncture combined with cognitive training can significantly improve the acute stroke patients with cognitive disorder.