RESUMO
La gammagrafía con radiotrazadores que tienen afinidad por los receptores de somatostatina se ha convertido en metodología eficaz para el diagnóstico y estadificación de los tumores neuroendocrinos. Se presenta un caso en el cual el procedimiento radioisotópico muestra su efectividad en la localización del tumor primario.
Somatostatin receptor scintigraphy has become an important tool for diagnosis and evaluation of neuroendocrine tumors. This case report shows about the importance of the radionuclide procedure for the localization of the primary tumor.
Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Carcinoma Medular , Carcinoma Medular/metabolismo , Compostos de Organotecnécio , Neoplasias da Glândula Tireoide , Neoplasias da Glândula Tireoide/metabolismo , Receptores de Somatostatina/metabolismo , Carcinoma Medular/patologia , Compostos de Organotecnécio/farmacocinética , Neoplasias da Glândula Tireoide/patologia , Octreotida/análogos & derivados , Octreotida/farmacocinética , Octreotida , Compostos Radiofarmacêuticos/farmacocinética , Compostos RadiofarmacêuticosRESUMO
Objective:To investigate the expression of FasL and its significance in thyroid adenocarcinomas. Methods: Immunohis-tochemical staining(S- P method) was used to detect expression of FasL in formalin - fixed and paraffin - embeded tissues from 27 cases of thyroid papillary adenocarcinomas(TPA) ,20 medullary carcinomas(MC)and 12 normal thyroid tissues. The relationship between the thyroid adenocarcinomas and the positive rates of FasL expression was analyzed. Results: FasL had various degrees of expression in TPA.The positive rate of high FasL expression was 81. 8% in group B,31. 2% in group A, with a significant difference of P